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FR2769322B1 - Nouveaux circovirus porcins, vaccins et reactifs de diagnostic - Google Patents

Nouveaux circovirus porcins, vaccins et reactifs de diagnostic

Info

Publication number
FR2769322B1
FR2769322B1 FR9800873A FR9800873A FR2769322B1 FR 2769322 B1 FR2769322 B1 FR 2769322B1 FR 9800873 A FR9800873 A FR 9800873A FR 9800873 A FR9800873 A FR 9800873A FR 2769322 B1 FR2769322 B1 FR 2769322B1
Authority
FR
France
Prior art keywords
vaccines
diagnostic reagents
porcine circoviruses
new porcine
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9800873A
Other languages
English (en)
Other versions
FR2769322A1 (fr
Inventor
Gordon Allan
Brian Meehan
Edward Clark
John Ellis
Deborah Haines
Lori Hassard
John Harding
Catherine Elisabeth Charreyre
Gilles Emile Chappuis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health France SAS
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Merial SAS
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9712382A external-priority patent/FR2769321B1/fr
Priority to UA2000042372A priority Critical patent/UA78180C2/uk
Application filed by Merial SAS, Merial Inc filed Critical Merial SAS
Priority to FR9800873A priority patent/FR2769322B1/fr
Priority to US09/082,558 priority patent/US6368601B1/en
Priority to US09/161,092 priority patent/US6391314B1/en
Priority to HU0800330A priority patent/HU230340B1/hu
Priority to AU93555/98A priority patent/AU756554C/en
Priority to EP03016998A priority patent/EP1386617B1/fr
Priority to KR1020007003628A priority patent/KR100736129B1/ko
Priority to DK98946547T priority patent/DK1019510T3/da
Priority to CN98810652A priority patent/CN100584948C/zh
Priority to HU0003756A priority patent/HU226247B1/hu
Priority to AT03016998T priority patent/ATE387914T1/de
Priority to DE69830858A priority patent/DE69830858D1/de
Priority to DE05014998T priority patent/DE05014998T1/de
Priority to DK05014998.8T priority patent/DK1741785T3/da
Priority to KR1020097009112A priority patent/KR100944144B1/ko
Priority to RU2000111496A priority patent/RU2283862C2/ru
Priority to DE69830858T priority patent/DE69830858T4/de
Priority to EP02017134A priority patent/EP1281760B9/fr
Priority to AT98946547T priority patent/ATE245191T1/de
Priority to KR1020067010174A priority patent/KR100854615B1/ko
Priority to KR1020087004310A priority patent/KR100904852B1/ko
Priority to EP05014998.8A priority patent/EP1741785B1/fr
Priority to CA002305623A priority patent/CA2305623C/fr
Priority to PT50149988T priority patent/PT1741785E/pt
Priority to ES03016998T priority patent/ES2302885T3/es
Priority to DE200512000009 priority patent/DE122005000009I1/de
Priority to BRPI9812845-0A priority patent/BR9812845B1/pt
Priority to DE69839227T priority patent/DE69839227T2/de
Priority to PT02017134T priority patent/PT1281760E/pt
Priority to DK03016998T priority patent/DK1386617T3/da
Priority to PT03016998T priority patent/PT1386617E/pt
Priority to ES05014998.8T priority patent/ES2524359T3/es
Priority to CN2008101690507A priority patent/CN101445802B/zh
Priority to CN200910252636.4A priority patent/CN101724606B/zh
Priority to ES02017134T priority patent/ES2246001T3/es
Priority to DE122008000069C priority patent/DE122008000069I1/de
Priority to PT98946547T priority patent/PT1019510E/pt
Priority to EP98946547A priority patent/EP1019510B1/fr
Priority to PCT/FR1998/002107 priority patent/WO1999018214A1/fr
Priority to ES98946547T priority patent/ES2203984T3/es
Priority to PL339631A priority patent/PL198506B1/pl
Priority to AT02017134T priority patent/ATE299531T1/de
Priority to DK02017134T priority patent/DK1281760T5/da
Priority to JP2000515010A priority patent/JP5008218B2/ja
Priority to DE69816460T priority patent/DE69816460T2/de
Publication of FR2769322A1 publication Critical patent/FR2769322A1/fr
Priority to US09/884,514 priority patent/US6660272B2/en
Application granted granted Critical
Publication of FR2769322B1 publication Critical patent/FR2769322B1/fr
Priority to US10/624,049 priority patent/US7122192B2/en
Priority to US10/653,849 priority patent/US7192594B2/en
Priority to US10/780,318 priority patent/US7211379B2/en
Priority to US11/107,219 priority patent/US20060029617A1/en
Priority to FR05C0021C priority patent/FR05C0021I2/fr
Priority to US11/217,562 priority patent/US7504206B2/en
Priority to CY20051101221T priority patent/CY1110359T1/el
Priority to US11/485,525 priority patent/US7803613B2/en
Priority to US11/485,240 priority patent/US7833783B2/en
Priority to US11/522,237 priority patent/US7803926B2/en
Priority to HK07101074.0A priority patent/HK1095161B/xx
Priority to JP2007254101A priority patent/JP4680245B2/ja
Priority to NL300326C priority patent/NL300326I2/nl
Priority to CY20081100583T priority patent/CY1108113T1/el
Priority to JP2011004965A priority patent/JP5362750B2/ja
Priority to JP2012060619A priority patent/JP2012193179A/ja
Priority to CY20141100947T priority patent/CY1115749T1/el
Priority to JP2014255849A priority patent/JP5869658B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A23C19/0321—Propionic acid bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A23C19/0323—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin using only lactic acid bacteria, e.g. Pediococcus and Leuconostoc species; Bifidobacteria; Microbial starters in general
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10061—Methods of inactivation or attenuation
    • C12N2750/10064—Methods of inactivation or attenuation by serial passage

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9800873A 1997-10-03 1998-01-22 Nouveaux circovirus porcins, vaccins et reactifs de diagnostic Expired - Lifetime FR2769322B1 (fr)

Priority Applications (65)

Application Number Priority Date Filing Date Title
UA2000042372A UA78180C2 (uk) 1997-10-03 1998-01-10 Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR9800873A FR2769322B1 (fr) 1997-10-03 1998-01-22 Nouveaux circovirus porcins, vaccins et reactifs de diagnostic
US09/082,558 US6368601B1 (en) 1997-10-03 1998-05-21 Porcine circovirus vaccine and diagnostics reagents
US09/161,092 US6391314B1 (en) 1997-10-03 1998-09-25 Porcine circoviruses vaccines diagnostic reagents
HU0800330A HU230340B1 (hu) 1997-10-03 1998-10-01 Újonnan izolált, sertésből származó cirkovírusokból származó szekvenciákat tartalmazó expressziós vektorok és ezeket tartalmazó vakcinák
AU93555/98A AU756554C (en) 1997-10-03 1998-10-01 Porcine circoviruses, vaccines and diagnostic reagents
EP03016998A EP1386617B1 (fr) 1997-10-03 1998-10-01 Méthode de diagnostic in vitro de l'infection par le circovirus porcin de type II et réactifs de diagnostic
KR1020007003628A KR100736129B1 (ko) 1997-10-03 1998-10-01 돼지 서코바이러스, 백신 및 진단시약
DK98946547T DK1019510T3 (da) 1997-10-03 1998-10-01 Vacciner på basis af porcint circovirus
CN98810652A CN100584948C (zh) 1997-10-03 1998-10-01 新猪环病毒、疫苗及诊断试剂
HU0003756A HU226247B1 (en) 1997-10-03 1998-10-01 Newly isolated porcine circoviruses, circovirus vaccines and diagnostic reagents
AT03016998T ATE387914T1 (de) 1997-10-03 1998-10-01 Verfahren zur in vitro-diagnose von infektionen durch schweinecircovirus vom typ ii und diagnostische reagenzien
DE69830858A DE69830858D1 (de) 1997-10-03 1998-10-01 Schweinecircoviren
DE05014998T DE05014998T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren, Nukleinsäuren, Polypeptide und Impfstoffe
DK05014998.8T DK1741785T3 (da) 1997-10-03 1998-10-01 Porcint circovirus, nukleinsyrer, polypeptider og vacciner
KR1020097009112A KR100944144B1 (ko) 1997-10-03 1998-10-01 돼지 서코바이러스, 백신 및 진단시약
RU2000111496A RU2283862C2 (ru) 1997-10-03 1998-10-01 Цирковирус свиней типа ii и его применение
DE69830858T DE69830858T4 (de) 1997-10-03 1998-10-01 Schweinecircoviren
EP02017134A EP1281760B9 (fr) 1997-10-03 1998-10-01 Circovirus porcins
AT98946547T ATE245191T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete impfstoffe
KR1020067010174A KR100854615B1 (ko) 1997-10-03 1998-10-01 돼지 서코바이러스, 백신 및 진단시약
KR1020087004310A KR100904852B1 (ko) 1997-10-03 1998-10-01 돼지 서코바이러스, 백신 및 진단시약
EP05014998.8A EP1741785B1 (fr) 1997-10-03 1998-10-01 Circovirus porcins, acides nucléiques, polypeptides et vaccins
CA002305623A CA2305623C (fr) 1997-10-03 1998-10-01 Circovirus porcins, vaccins et reactifs de diagnostic
PT50149988T PT1741785E (pt) 1997-10-03 1998-10-01 Circovírus porcino, ácidos nucleicos, polipéptidos e vacinas
ES03016998T ES2302885T3 (es) 1997-10-03 1998-10-01 Metodo de diagnostico in vitro de la infeccion por circovirus porcino de tipo ii y reactivos de diagnostico.
DE200512000009 DE122005000009I1 (de) 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete Impfstoffe.
BRPI9812845-0A BR9812845B1 (pt) 1997-10-03 1998-10-01 vacina induzindo uma resposta imune ao circovìrus suìno do tipo ii.
DE69839227T DE69839227T2 (de) 1997-10-03 1998-10-01 Verfahren zur in vitro-Diagnose von Infektionen durch Schweinecircovirus vom Typ II und diagnostische Reagenzien
PT02017134T PT1281760E (pt) 1997-10-03 1998-10-01 Circovirus porcinos, vacinas e reagentes de diagnostico
DK03016998T DK1386617T3 (da) 1997-10-03 1998-10-01 Fremgangsmåde til in vitro-diagnose af type II porcin circovirusinfektion og diagnostiske reagenser
PT03016998T PT1386617E (pt) 1997-10-03 1998-10-01 Método para a diagnose in vitro de infecção por circovírus porcino do tipo ii e reagentes de diagnóstico
ES05014998.8T ES2524359T3 (es) 1997-10-03 1998-10-01 Circovirus porcino, ácidos nucleicos, polipéptidos y vacunas
CN2008101690507A CN101445802B (zh) 1997-10-03 1998-10-01 新猪环病毒、疫苗及诊断试剂
CN200910252636.4A CN101724606B (zh) 1997-10-03 1998-10-01 新猪环病毒、疫苗及诊断试剂
ES02017134T ES2246001T3 (es) 1997-10-03 1998-10-01 Circovirus porcino.
DE122008000069C DE122008000069I1 (de) 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete impfstoffe
PT98946547T PT1019510E (pt) 1997-10-03 1998-10-01 Vacinas derivadas de circovirus suinos
EP98946547A EP1019510B1 (fr) 1997-10-03 1998-10-01 Vaccins a base de circovirus porcins
PCT/FR1998/002107 WO1999018214A1 (fr) 1997-10-03 1998-10-01 Circovirus porcins, vaccins et reactifs de diagnostic
ES98946547T ES2203984T3 (es) 1997-10-03 1998-10-01 Vacunas a base de circovirus porcinos.
PL339631A PL198506B1 (pl) 1997-10-03 1998-10-01 Preparat wyizolowanego świńskiego cirkowirusa typu II, sposób wytwarzania świńskiego cirkowirusa typu II, ekstrakt albo nadsącz komórkowy, preparat antygenowy, szczepionka, przeciwciała monoklonalne albo poliklonalne, wyizolowany świński cirkowirus typu II, fragment kwasu nukleinowego, polipeptyd, wektor, szczepionka, sposób diagnozowania infekcji, preparat przeciwciał, preparat antygenowy, zestaw do diagnozy
AT02017134T ATE299531T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren
DK02017134T DK1281760T5 (da) 1997-10-03 1998-10-01 Porcine circovirus
JP2000515010A JP5008218B2 (ja) 1997-10-03 1998-10-01 ブタサーコウイルス、ワクチンおよび診断試薬
DE69816460T DE69816460T2 (de) 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete impfstoffe
US09/884,514 US6660272B2 (en) 1997-10-03 2001-06-19 Porcine circoviruses, vaccines and diagnostic reagents
US10/624,049 US7122192B2 (en) 1997-10-03 2003-07-21 Porcine circoviruses, vaccines and diagnostic reagents
US10/653,849 US7192594B2 (en) 1997-10-03 2003-09-02 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US10/780,318 US7211379B2 (en) 1997-10-03 2004-02-17 Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
US11/107,219 US20060029617A1 (en) 1997-10-03 2005-04-15 Porcine circovirus and Helicobacter combination vaccines and methods of use
FR05C0021C FR05C0021I2 (fr) 1997-10-03 2005-04-26
US11/217,562 US7504206B2 (en) 1997-10-03 2005-09-01 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
CY20051101221T CY1110359T1 (el) 1997-10-03 2005-10-07 Εμβολια με βαση σιρκοϊους χοιρων
US11/485,525 US7803613B2 (en) 1997-10-03 2006-07-12 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US11/485,240 US7833783B2 (en) 1997-10-03 2006-07-12 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US11/522,237 US7803926B2 (en) 1997-10-03 2006-09-15 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
HK07101074.0A HK1095161B (en) 1997-10-03 2007-01-31 Porcine circoviruses, nucleic acids, polypeptides and vaccines
JP2007254101A JP4680245B2 (ja) 1997-10-03 2007-09-28 ブタサーコウイルス、ワクチンおよび診断試薬
NL300326C NL300326I2 (nl) 1997-10-03 2007-12-18 Circovirus bij varkens, vaccins en diagnostische reagentia
CY20081100583T CY1108113T1 (el) 1997-10-03 2008-06-03 Μεθοδος διαγνωσεως ιν vitro της μολυνσεως απο σιρκoïο χοιρων τυπου ιι και αντιδραστηρια διαγνωσεως
JP2011004965A JP5362750B2 (ja) 1997-10-03 2011-01-13 ブタサーコウイルス、ワクチンおよび診断試薬
JP2012060619A JP2012193179A (ja) 1997-10-03 2012-03-16 ブタサーコウイルス、ワクチンおよび診断試薬
CY20141100947T CY1115749T1 (el) 1997-10-03 2014-11-13 Κυκλοϊος χοιρων, νουκλεϊνικα οξεα, πολυπεπτιδια και εμβολια
JP2014255849A JP5869658B2 (ja) 1997-10-03 2014-12-18 ブタサーコウイルス、ワクチンおよび診断試薬

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US7279166B2 (en) 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
HUE025537T2 (en) * 2004-12-30 2016-05-30 Boehringer Ingelheim Vetmedica Inc PCV2-immunogenic compositions and methods for preparing such compositions
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
CL2008003813A1 (es) * 2007-12-21 2009-03-20 Zoetis W Llc Circovirus porcino; molecula de acido nucleico que lo codifica; composicion inmunogenica que lo comprende; metodo para inmunizar un cerdo contra la infeccion virica o para prevenir el sindrome postdestete de desgaste multi-sistemico (pmsw);y metodo para determinar si un mamifero tiene o esta en riesgo de desarrollar pmsw.
BR102013001893B1 (pt) * 2013-01-25 2022-01-25 Fundação De Amparo À Pesquisa Do Estado De Minas Gerais - Fapemig Antígenos recombinantes do porcine circovirus 2 (pcv-2) para formulações vacinais, kit de diagnóstico e uso
CA2925281C (fr) 2013-09-25 2022-05-03 Zoetis Services Llc Composition vaccinale divergente anti-pcv2b et ses procedes d'utilisation
EP3362467A4 (fr) * 2015-10-16 2019-06-12 Kansas State University Research Foundation Compositions immunogènes contre le circovirus porcin de type 3 et procédés de fabrication et d'utilisation associés
RU2695330C1 (ru) * 2018-06-19 2019-07-23 Федеральное государственное бюджетное научное учреждение "Федеральный научный центр - Всероссийский научно-исследовательский институт экспериментальной ветеринарии имени К.И. Скрябина и Я.Р. Коваленко Российской академии наук" Способ диагностики цирковирусной инфекции свиней второго типа прямым иммуногистохимическим анализом на основании моноклональных антител
RU2697849C1 (ru) * 2019-04-26 2019-08-21 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский и технологический институт биологической промышленности" (ФГБНУ ВНИТИБП) Способ диагностики цирковируса свиней
RU2746142C1 (ru) * 2020-06-23 2021-04-07 Федеральное Казенное Предприятие "Щелковский Биокомбинат" Штамм "pcv2/shbc" цирковируса свиней для производства профилактических и диагностических препаратов

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US7741026B2 (en) 1997-12-05 2010-06-22 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7758865B2 (en) 1997-12-05 2010-07-20 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7951907B2 (en) 1997-12-05 2011-05-31 Wyeth Llc Circovirus sequences associated with piglet weight loss disease (PWD)
US8124723B2 (en) 1997-12-05 2012-02-28 Wyeth Llc Circovirus sequences associated with piglet weight loss disease (PWD)
US8415525B2 (en) 1997-12-05 2013-04-09 Zoetis W Llc Circovirus sequences associated with piglet weight loss disease (PWD)
US8715690B2 (en) 1997-12-05 2014-05-06 Zoetis W Llc Circovirus sequences associated with piglet weight loss disease (PWD)
US8916353B2 (en) 1997-12-05 2014-12-23 Zoetis W Llc Circovirus sequences associated with piglet weight loss disease (PWD)

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