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FR2767336B1 - Vecteurs recombinants, polynucleotide codant pour un polypeptide pd428 de 12kd de mycobacteries appartenant au complexe de mycobacterium tuberculosis et applications au diagnostic et a la prevention de la tuberculose - Google Patents

Vecteurs recombinants, polynucleotide codant pour un polypeptide pd428 de 12kd de mycobacteries appartenant au complexe de mycobacterium tuberculosis et applications au diagnostic et a la prevention de la tuberculose

Info

Publication number
FR2767336B1
FR2767336B1 FR9710404A FR9710404A FR2767336B1 FR 2767336 B1 FR2767336 B1 FR 2767336B1 FR 9710404 A FR9710404 A FR 9710404A FR 9710404 A FR9710404 A FR 9710404A FR 2767336 B1 FR2767336 B1 FR 2767336B1
Authority
FR
France
Prior art keywords
tuberculosis
polypeptide
diagnosis
prevention
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9710404A
Other languages
English (en)
Other versions
FR2767336A1 (fr
Inventor
Brigitte Gicquel
Denis Portnoi
Eng Mong Lim
Vladimir Pelicic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur filed Critical Institut Pasteur
Priority to FR9710404A priority Critical patent/FR2767336B1/fr
Priority to FR9711325A priority patent/FR2767337B1/fr
Priority to NZ519053A priority patent/NZ519053A/en
Priority to AT98942748T priority patent/ATE393828T1/de
Priority to DK98942748T priority patent/DK1003888T3/da
Priority to NZ529503A priority patent/NZ529503A/en
Priority to DE69839426T priority patent/DE69839426T2/de
Priority to PT98942748T priority patent/PT1003888E/pt
Priority to EP08154762A priority patent/EP1950221A3/fr
Priority to PCT/FR1998/001813 priority patent/WO1999009186A2/fr
Priority to ES98942748T priority patent/ES2306478T3/es
Priority to JP2000509849A priority patent/JP2002534956A/ja
Priority to CA002301374A priority patent/CA2301374A1/fr
Priority to EP98942748A priority patent/EP1003888B1/fr
Priority to AU90765/98A priority patent/AU759724B2/en
Priority to NZ503316A priority patent/NZ503316A/xx
Publication of FR2767336A1 publication Critical patent/FR2767336A1/fr
Priority to US09/855,604 priority patent/US7244613B2/en
Application granted granted Critical
Publication of FR2767336B1 publication Critical patent/FR2767336B1/fr
Priority to US11/329,260 priority patent/US20070015173A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR9710404A 1997-08-14 1997-08-14 Vecteurs recombinants, polynucleotide codant pour un polypeptide pd428 de 12kd de mycobacteries appartenant au complexe de mycobacterium tuberculosis et applications au diagnostic et a la prevention de la tuberculose Expired - Fee Related FR2767336B1 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR9710404A FR2767336B1 (fr) 1997-08-14 1997-08-14 Vecteurs recombinants, polynucleotide codant pour un polypeptide pd428 de 12kd de mycobacteries appartenant au complexe de mycobacterium tuberculosis et applications au diagnostic et a la prevention de la tuberculose
FR9711325A FR2767337B1 (fr) 1997-08-14 1997-09-11 Sequences nucleiques de polypeptides exportes de mycobacteri es, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose
NZ519053A NZ519053A (en) 1997-08-14 1998-08-04 Polypeptide nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
CA002301374A CA2301374A1 (fr) 1997-08-14 1998-08-14 Sequences nucleiques de polypeptides exportes de mycobacteries, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose
NZ529503A NZ529503A (en) 1997-08-14 1998-08-14 Polypeptide nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
DE69839426T DE69839426T2 (de) 1997-08-14 1998-08-14 Nukleotidsequenzen, die für sekretierte polypeptide aus mycobacterium kodieren, vektoren, die diese enthalten, und anwendungen zur diagnostik und verhütung von tuberkulose
PT98942748T PT1003888E (pt) 1997-08-14 1998-08-14 Sequências nucleicas de polipéptidos exportados de micobactérias, vectores compreendendo-as e aplicações para o diagnóstico e a prevenção da tuberculose
EP08154762A EP1950221A3 (fr) 1997-08-14 1998-08-14 Séquences génomiques de polypeptides exportés de mycobactéries, vecteurs les comprenant et applications au diagnostic et à la prévention de la tuberculose
PCT/FR1998/001813 WO1999009186A2 (fr) 1997-08-14 1998-08-14 Sequences nucleiques de polypeptides exportes de mycobacteries, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose
ES98942748T ES2306478T3 (es) 1997-08-14 1998-08-14 Secuencias nucleidas de polipeptidos exportados de micobacterias, vectores que los comprenden y aplicaciones para el diagnostico y para la tuberculosis.
AT98942748T ATE393828T1 (de) 1997-08-14 1998-08-14 Nukleotidsequenzen, die für sekretierte polypeptide aus mycobacterium kodieren, vektoren, die diese enthalten, und anwendungen zur diagnostik und verhütung von tuberkulose
DK98942748T DK1003888T3 (da) 1997-08-14 1998-08-14 Nukleinsyresekvenser for polypeptider eksporteret fra mykobakterier, vektorer omfattende disse samt anvendelser til diagnosticering og forebyggelse af tuberkolose
EP98942748A EP1003888B1 (fr) 1997-08-14 1998-08-14 Sequences nucleiques de polypeptides exportes de mycobacteries, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose
AU90765/98A AU759724B2 (en) 1997-08-14 1998-08-14 Polypeptide nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
NZ503316A NZ503316A (en) 1997-08-14 1998-08-14 Polypeptide and nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
JP2000509849A JP2002534956A (ja) 1997-08-14 1998-08-14 マイコバクテリアから輸送されるポリペプチド核酸配列、それを含んでなるベクター、および結核の診断および予防のための使用
US09/855,604 US7244613B2 (en) 1997-08-14 2001-05-16 Polypeptide nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
US11/329,260 US20070015173A1 (en) 1997-08-14 2006-01-11 Polypeptide nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710404A FR2767336B1 (fr) 1997-08-14 1997-08-14 Vecteurs recombinants, polynucleotide codant pour un polypeptide pd428 de 12kd de mycobacteries appartenant au complexe de mycobacterium tuberculosis et applications au diagnostic et a la prevention de la tuberculose

Publications (2)

Publication Number Publication Date
FR2767336A1 FR2767336A1 (fr) 1999-02-19
FR2767336B1 true FR2767336B1 (fr) 2001-05-18

Family

ID=9510323

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9710404A Expired - Fee Related FR2767336B1 (fr) 1997-08-14 1997-08-14 Vecteurs recombinants, polynucleotide codant pour un polypeptide pd428 de 12kd de mycobacteries appartenant au complexe de mycobacterium tuberculosis et applications au diagnostic et a la prevention de la tuberculose

Country Status (1)

Country Link
FR (1) FR2767336B1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2767337B1 (fr) * 1997-08-14 2002-07-05 Pasteur Institut Sequences nucleiques de polypeptides exportes de mycobacteri es, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724183B1 (fr) * 1994-09-02 1997-04-11 Pasteur Institut Vecteurs de criblage et/ou d'expression fonctionnels chez les mycobacteries - utilisation pour l'identification et l'expression de polypeptides exportes

Also Published As

Publication number Publication date
FR2767336A1 (fr) 1999-02-19

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Effective date: 20100430