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FR2766572B1 - Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anti-cancereux - Google Patents

Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anti-cancereux

Info

Publication number
FR2766572B1
FR2766572B1 FR9709563A FR9709563A FR2766572B1 FR 2766572 B1 FR2766572 B1 FR 2766572B1 FR 9709563 A FR9709563 A FR 9709563A FR 9709563 A FR9709563 A FR 9709563A FR 2766572 B1 FR2766572 B1 FR 2766572B1
Authority
FR
France
Prior art keywords
tubulin
cancer
screening
applications
appropriate cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9709563A
Other languages
English (en)
Other versions
FR2766572A1 (fr
Inventor
Didier Job
Laurence Lafanechere
Robert L Margolis
Jurgen Wehland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR9709563A priority Critical patent/FR2766572B1/fr
Priority to PCT/FR1998/001645 priority patent/WO1999005522A1/fr
Priority to CA002299169A priority patent/CA2299169A1/fr
Publication of FR2766572A1 publication Critical patent/FR2766572A1/fr
Application granted granted Critical
Publication of FR2766572B1 publication Critical patent/FR2766572B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/9015—Ligases (6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR9709563A 1997-07-28 1997-07-28 Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anti-cancereux Expired - Fee Related FR2766572B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9709563A FR2766572B1 (fr) 1997-07-28 1997-07-28 Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anti-cancereux
PCT/FR1998/001645 WO1999005522A1 (fr) 1997-07-28 1998-07-24 Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anticancereux
CA002299169A CA2299169A1 (fr) 1997-07-28 1998-07-24 Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anticancereux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9709563A FR2766572B1 (fr) 1997-07-28 1997-07-28 Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anti-cancereux

Publications (2)

Publication Number Publication Date
FR2766572A1 FR2766572A1 (fr) 1999-01-29
FR2766572B1 true FR2766572B1 (fr) 1999-10-08

Family

ID=9509701

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9709563A Expired - Fee Related FR2766572B1 (fr) 1997-07-28 1997-07-28 Utilisation de cellules appropriees pour le criblage d'inhibiteurs de la tubuline-carboxypeptidase et applications de ces derniers comme anti-cancereux

Country Status (3)

Country Link
CA (1) CA2299169A1 (fr)
FR (1) FR2766572B1 (fr)
WO (1) WO1999005522A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2645095A1 (fr) * 2006-03-08 2007-09-13 University Of Maryland, Baltimore Inhibition de protrusion de microtubule dans des cellules cancereuses
EP3431491A1 (fr) * 2017-07-18 2019-01-23 Centre National De La Recherche Scientifique Procédés de purification de protéines ayant une activité carboxypeptidase de tubuline et leurs inhibiteurs à base peptidique
EP3701027A1 (fr) * 2017-10-26 2020-09-02 Les Laboratoires Servier SAS Méthodes et compositions pharmaceutiques pour le traitement des maladies associées aux tubulines carboxypeptidases

Also Published As

Publication number Publication date
WO1999005522A1 (fr) 1999-02-04
FR2766572A1 (fr) 1999-01-29
CA2299169A1 (fr) 1999-02-04

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Legal Events

Date Code Title Description
ST Notification of lapse