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FR2697841B1 - New taxane derivatives, their preparation and the pharmaceutical compositions containing them. - Google Patents

New taxane derivatives, their preparation and the pharmaceutical compositions containing them.

Info

Publication number
FR2697841B1
FR2697841B1 FR9213586A FR9213586A FR2697841B1 FR 2697841 B1 FR2697841 B1 FR 2697841B1 FR 9213586 A FR9213586 A FR 9213586A FR 9213586 A FR9213586 A FR 9213586A FR 2697841 B1 FR2697841 B1 FR 2697841B1
Authority
FR
France
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
taxane derivatives
new taxane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9213586A
Other languages
French (fr)
Other versions
FR2697841A1 (en
Inventor
Jean-Dominique Bourzat
Alain Commercon
Dominique Deprez
Jean-Pierre Publicani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR9213586A priority Critical patent/FR2697841B1/en
Priority to MX9306883A priority patent/MX9306883A/en
Priority to ZA938366A priority patent/ZA938366B/en
Priority to PCT/FR1993/001102 priority patent/WO1994011547A1/en
Priority to RU95112464/04A priority patent/RU95112464A/en
Priority to CA002149240A priority patent/CA2149240A1/en
Priority to AU54257/94A priority patent/AU5425794A/en
Priority to EP93924688A priority patent/EP0667922A1/en
Priority to KR1019950701883A priority patent/KR950704540A/en
Priority to JP6511786A priority patent/JPH08503261A/en
Priority to SK608-95A priority patent/SK60895A3/en
Priority to PL93308957A priority patent/PL308957A1/en
Priority to CZ951224A priority patent/CZ122495A3/en
Priority to FI952294A priority patent/FI952294A7/en
Publication of FR2697841A1 publication Critical patent/FR2697841A1/en
Application granted granted Critical
Publication of FR2697841B1 publication Critical patent/FR2697841B1/en
Priority to NO951772A priority patent/NO951772L/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
    • C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
    • C25B11/042—Electrodes formed of a single material
    • C25B11/046—Alloys
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/17—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
    • C25B9/19—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
    • C25B9/23—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Metallurgy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR9213586A 1992-11-12 1992-11-12 New taxane derivatives, their preparation and the pharmaceutical compositions containing them. Expired - Fee Related FR2697841B1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR9213586A FR2697841B1 (en) 1992-11-12 1992-11-12 New taxane derivatives, their preparation and the pharmaceutical compositions containing them.
MX9306883A MX9306883A (en) 1992-11-12 1993-11-04 NEW DERIVATIVES OF TAXANE, PROCEDURE FOR THEIR OBTAINING AND PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM.
ZA938366A ZA938366B (en) 1992-11-12 1993-11-09 Process for the preparation of taxane derivatives new taxanes thereby obtained and compositions containing them
CZ951224A CZ122495A3 (en) 1992-11-12 1993-11-10 Process for preparing taxan derivatives
CA002149240A CA2149240A1 (en) 1992-11-12 1993-11-10 Process for preparing taxane derivatives; new taxanes thus produced and antitumoral and antileukemia compositions containing the same
AU54257/94A AU5425794A (en) 1992-11-12 1993-11-10 Process for the preparation of taxane derivatives, novel taxanes so obtained and antitumour and antileukaemia compositions containing same
EP93924688A EP0667922A1 (en) 1992-11-12 1993-11-10 Process for the preparation of taxane derivatives, novel taxanes so obtained and antitumour and antileukaemia compositions containing same
KR1019950701883A KR950704540A (en) 1992-11-12 1993-11-10 PROCESS FOR THE PREPARATION OF TAXANE DERIVATIVES, NOVEL TAXANES SO OBTAINED AND ANTITUMOUR AND ANTILEUKAEMIA COMPOSITIONS CONTAINING SAME
PCT/FR1993/001102 WO1994011547A1 (en) 1992-11-12 1993-11-10 Process for the preparation of taxane derivatives, novel taxanes so obtained and antitumour and antileukaemia compositions containing same
SK608-95A SK60895A3 (en) 1992-11-12 1993-11-10 Taxane derivatives and process for their preparation
PL93308957A PL308957A1 (en) 1992-11-12 1993-11-10 Method of obtaining taxane derivatives, novel taxanes obtained thereby and composition containing suchtaxanes
RU95112464/04A RU95112464A (en) 1992-11-12 1993-11-10 Process for preparing taxane derivatives
FI952294A FI952294A7 (en) 1992-11-12 1993-11-10 Process for preparing taxane derivatives, novel taxanes thus obtained and antitumor and antileukemic compositions containing them
JP6511786A JPH08503261A (en) 1992-11-12 1993-11-10 Process for producing taxane derivative, novel taxane obtained thereby, and antitumor and antileukemia composition containing them
NO951772A NO951772L (en) 1992-11-12 1995-05-05 Process for the preparation of taxane derivatives, the thus obtained new taxanes as well as anti-tumor and anti-leukemia preparations containing the taxanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213586A FR2697841B1 (en) 1992-11-12 1992-11-12 New taxane derivatives, their preparation and the pharmaceutical compositions containing them.

Publications (2)

Publication Number Publication Date
FR2697841A1 FR2697841A1 (en) 1994-05-13
FR2697841B1 true FR2697841B1 (en) 1995-01-13

Family

ID=9435452

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9213586A Expired - Fee Related FR2697841B1 (en) 1992-11-12 1992-11-12 New taxane derivatives, their preparation and the pharmaceutical compositions containing them.

Country Status (15)

Country Link
EP (1) EP0667922A1 (en)
JP (1) JPH08503261A (en)
KR (1) KR950704540A (en)
AU (1) AU5425794A (en)
CA (1) CA2149240A1 (en)
CZ (1) CZ122495A3 (en)
FI (1) FI952294A7 (en)
FR (1) FR2697841B1 (en)
MX (1) MX9306883A (en)
NO (1) NO951772L (en)
PL (1) PL308957A1 (en)
RU (1) RU95112464A (en)
SK (1) SK60895A3 (en)
WO (1) WO1994011547A1 (en)
ZA (1) ZA938366B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
FR2710642B1 (en) * 1993-09-29 1995-11-17 Rhone Poulenc Rorer Sa New taxoids, their preparation and the pharmaceutical compositions containing them.
FR2711369B1 (en) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa New taxoids, their preparation and the compositions containing them.
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
CA2255615C (en) * 1996-05-22 2006-08-29 Neuromedica, Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and docetaxel
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US8309603B2 (en) 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
ES2631152T3 (en) * 2004-01-22 2017-08-28 University Of Miami Topical or intravenous Q10 coenzyme formulations for use in cancer treatment
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
US10519504B2 (en) 2009-05-11 2019-12-31 Berg Llc Methods for treatment of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
EP2694463B8 (en) 2011-04-04 2019-10-09 Berg LLC Treating central nervous system tumors with coenzyme q10
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
EA032775B1 (en) 2013-04-08 2019-07-31 Берг Ллк Methofs of treating cancer using coenzyme q10 combination therapies
WO2015035094A1 (en) 2013-09-04 2015-03-12 Berg Llc Methods of treatment of cancer by continuous infusion of coenzyme q10
WO2017087576A1 (en) 2015-11-16 2017-05-26 Berg Llc Methods of treatment of temozolomide-resistant glioma using coenzyme q10

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
FR2697841A1 (en) 1994-05-13
WO1994011547A1 (en) 1994-05-26
MX9306883A (en) 1995-01-31
KR950704540A (en) 1995-11-20
RU95112464A (en) 1997-02-20
SK60895A3 (en) 1996-03-06
JPH08503261A (en) 1996-04-09
CA2149240A1 (en) 1994-05-26
ZA938366B (en) 1994-06-13
FI952294A0 (en) 1995-05-11
EP0667922A1 (en) 1995-08-23
FI952294L (en) 1995-05-11
NO951772D0 (en) 1995-05-05
FI952294A7 (en) 1995-05-11
CZ122495A3 (en) 1995-12-13
AU5425794A (en) 1994-06-08
NO951772L (en) 1995-05-05
PL308957A1 (en) 1995-09-04

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Legal Events

Date Code Title Description
ST Notification of lapse