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FR2694292B1 - Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament. - Google Patents

Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament.

Info

Publication number
FR2694292B1
FR2694292B1 FR9209382A FR9209382A FR2694292B1 FR 2694292 B1 FR2694292 B1 FR 2694292B1 FR 9209382 A FR9209382 A FR 9209382A FR 9209382 A FR9209382 A FR 9209382A FR 2694292 B1 FR2694292 B1 FR 2694292B1
Authority
FR
France
Prior art keywords
thione
benzimidazole
medicaments
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9209382A
Other languages
English (en)
Other versions
FR2694292A1 (fr
Inventor
Ramon Merce-Vidal
Jordi Frigola-Constansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Priority to FR9209382A priority Critical patent/FR2694292B1/fr
Priority to ES9301754A priority patent/ES2103221B1/es
Publication of FR2694292A1 publication Critical patent/FR2694292A1/fr
Application granted granted Critical
Publication of FR2694292B1 publication Critical patent/FR2694292B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9209382A 1992-07-29 1992-07-29 Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament. Expired - Fee Related FR2694292B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9209382A FR2694292B1 (fr) 1992-07-29 1992-07-29 Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament.
ES9301754A ES2103221B1 (es) 1992-07-29 1993-07-28 Nuevos derivados de bencimidazol-2-tiona, su preparacion y su aplicacion como medicamentos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9209382A FR2694292B1 (fr) 1992-07-29 1992-07-29 Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament.

Publications (2)

Publication Number Publication Date
FR2694292A1 FR2694292A1 (fr) 1994-02-04
FR2694292B1 true FR2694292B1 (fr) 1994-10-21

Family

ID=9432404

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9209382A Expired - Fee Related FR2694292B1 (fr) 1992-07-29 1992-07-29 Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament.

Country Status (2)

Country Link
ES (1) ES2103221B1 (fr)
FR (1) FR2694292B1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0512046A (pt) 2004-06-15 2008-02-06 Pfizer derivados de ácido benzimidazolona carboxìlico
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
EA012615B1 (ru) 2005-02-22 2009-10-30 Пфайзер Инк. Производные оксииндола в качестве агонистов 5-htрецептора

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2053451T3 (es) * 1986-01-07 1994-08-01 Beecham Group Plc Un procedimiento para la preparacion de un compuesto que tiene propiedades farmacologicas utiles.
IT1231413B (it) * 1987-09-23 1991-12-04 Angeli Inst Spa Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht

Also Published As

Publication number Publication date
ES2103221A1 (es) 1997-09-01
FR2694292A1 (fr) 1994-02-04
ES2103221B1 (es) 1998-07-01

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Legal Events

Date Code Title Description
ST Notification of lapse