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FR2640625B2 - NOVEL OPTICALLY ACTIVE COMPOUNDS DERIVED FROM INDANE, THEIR APPLICATION AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NOVEL OPTICALLY ACTIVE COMPOUNDS DERIVED FROM INDANE, THEIR APPLICATION AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
FR2640625B2
FR2640625B2 FR888816605A FR8816605A FR2640625B2 FR 2640625 B2 FR2640625 B2 FR 2640625B2 FR 888816605 A FR888816605 A FR 888816605A FR 8816605 A FR8816605 A FR 8816605A FR 2640625 B2 FR2640625 B2 FR 2640625B2
Authority
FR
France
Prior art keywords
indane
drugs
application
pharmaceutical compositions
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR888816605A
Other languages
French (fr)
Other versions
FR2640625A2 (en
Inventor
Francois Clemence
Michel Fortin
Gilles Hamon
Odile Le Martret
Anne-Marie Moura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8611927A external-priority patent/FR2603035B1/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR888816605A priority Critical patent/FR2640625B2/en
Priority to DK626889A priority patent/DK626889A/en
Priority to JP1322788A priority patent/JP2753591B2/en
Priority to ZA899616A priority patent/ZA899616B/en
Priority to DE89403506T priority patent/DE68909757T2/en
Priority to EP89403506A priority patent/EP0374054B1/en
Priority to IE402789A priority patent/IE65151B1/en
Priority to HU631/89A priority patent/HU219446B/en
Priority to AT89403506T priority patent/ATE95517T1/en
Priority to AU46802/89A priority patent/AU630136B2/en
Priority to CA002005626A priority patent/CA2005626A1/en
Priority to ES89403506T priority patent/ES2059805T3/en
Publication of FR2640625A2 publication Critical patent/FR2640625A2/en
Publication of FR2640625B2 publication Critical patent/FR2640625B2/en
Application granted granted Critical
Priority to US08/096,034 priority patent/US5436244A/en
Priority to US08/105,329 priority patent/US5348971A/en
Priority to BG098525A priority patent/BG61121B1/en
Priority to HU95P/P00668P priority patent/HU211609A9/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR888816605A 1986-08-21 1988-12-16 NOVEL OPTICALLY ACTIVE COMPOUNDS DERIVED FROM INDANE, THEIR APPLICATION AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Expired - Lifetime FR2640625B2 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR888816605A FR2640625B2 (en) 1986-08-21 1988-12-16 NOVEL OPTICALLY ACTIVE COMPOUNDS DERIVED FROM INDANE, THEIR APPLICATION AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DK626889A DK626889A (en) 1988-12-16 1989-12-12 INDANDER DERIVATIVES, THEIR PREPARATION AND MEDICINES WITH CONTENTS
JP1322788A JP2753591B2 (en) 1988-12-16 1989-12-14 Use of compounds derived from indane as medicaments and pharmaceutical compositions containing them
AT89403506T ATE95517T1 (en) 1988-12-16 1989-12-15 INDANDERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND INTERMEDIATE PRODUCTS OBTAINED, THEIR USE AS MEDICINAL PRODUCTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
DE89403506T DE68909757T2 (en) 1988-12-16 1989-12-15 Indane derivatives, processes for their preparation and intermediates obtained, their use as medicaments and pharmaceutical compositions containing them.
EP89403506A EP0374054B1 (en) 1988-12-16 1989-12-15 Indane derivatives, process for their preparation and intermediates obtained, their use as medicines, and pharmaceutical compositions containing them
IE402789A IE65151B1 (en) 1988-12-16 1989-12-15 New compounds derived from indane their preparation process and intermediates their use as medicaments and the pharmaceutical compositions containing them
HU631/89A HU219446B (en) 1988-12-16 1989-12-15 Indane derivatives, pharmaceutical compositions containing them and process for producing them
ZA899616A ZA899616B (en) 1988-12-16 1989-12-15 Compounds derived from indane,their preparation process and intermediates,their use as medicaments and the pharmaceutical compositions containing them
AU46802/89A AU630136B2 (en) 1988-12-16 1989-12-15 New compounds derived from indane, their preparation process and intermediates, their use as medicaments and the pharmaceutical compositions containing them
CA002005626A CA2005626A1 (en) 1988-12-16 1989-12-15 New indane derivatives compositions, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing the same
ES89403506T ES2059805T3 (en) 1988-12-16 1989-12-15 COMPOUNDS DERIVED FROM INDANO, ITS PROCEDURE AND THE INTERMEDIATE PRODUCTS FOR ITS PREPARATION, ITS APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
US08/096,034 US5436244A (en) 1988-12-16 1993-07-22 Indane derivatives and analgesic and diuretic compositions thereof
US08/105,329 US5348971A (en) 1988-12-16 1993-08-09 Indanes useful as analgesics
BG098525A BG61121B1 (en) 1988-12-16 1994-02-23 COMPOUNDS DERIVATIVES OF INDANA, METHOD OF PREPARATION AND INTERMEDIATE PRODUCTS IN THE PREPARATION, THEIR APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HU95P/P00668P HU211609A9 (en) 1988-12-16 1995-06-30 Indan derivatives, process and intermediates to the production thereof, their use as medicament and pharmaceutical compositions containing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8611927A FR2603035B1 (en) 1986-08-21 1986-08-21 NEW INDANE DERIVATIVES, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR888816605A FR2640625B2 (en) 1986-08-21 1988-12-16 NOVEL OPTICALLY ACTIVE COMPOUNDS DERIVED FROM INDANE, THEIR APPLICATION AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2640625A2 FR2640625A2 (en) 1990-06-22
FR2640625B2 true FR2640625B2 (en) 1993-05-21

Family

ID=26225446

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888816605A Expired - Lifetime FR2640625B2 (en) 1986-08-21 1988-12-16 NOVEL OPTICALLY ACTIVE COMPOUNDS DERIVED FROM INDANE, THEIR APPLICATION AS DRUGS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (1)

Country Link
FR (1) FR2640625B2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1109080A (en) * 1978-05-30 1981-09-15 Hideo Kato Indanamine derivatives
GB2096607B (en) * 1981-04-09 1985-02-27 Upjohn Co Aminocycloalkyl amides
US4876269A (en) * 1986-09-10 1989-10-24 E. I. Du Pont De Nemours And Company Benoz-fused cycloalkane trans-1,2-diamine derivatives

Also Published As

Publication number Publication date
FR2640625A2 (en) 1990-06-22

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