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FR2565230B3 - Derives de (1h-dihydro-4,5 imidazolyl-2)-2 hexahydro-1,2,4,5,6,7 azepino (3,2,1-hi) indole, leur preparation et leur application en therapeutique - Google Patents

Derives de (1h-dihydro-4,5 imidazolyl-2)-2 hexahydro-1,2,4,5,6,7 azepino (3,2,1-hi) indole, leur preparation et leur application en therapeutique

Info

Publication number
FR2565230B3
FR2565230B3 FR8408726A FR8408726A FR2565230B3 FR 2565230 B3 FR2565230 B3 FR 2565230B3 FR 8408726 A FR8408726 A FR 8408726A FR 8408726 A FR8408726 A FR 8408726A FR 2565230 B3 FR2565230 B3 FR 2565230B3
Authority
FR
France
Prior art keywords
azepino
hexahydro
imidazolyl
dihydro
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8408726A
Other languages
English (en)
Other versions
FR2565230A1 (fr
Inventor
Dennis Bigg
Claude Morel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR8408726A priority Critical patent/FR2565230B3/fr
Priority to AT84402019T priority patent/ATE34392T1/de
Priority to EP84402019A priority patent/EP0139584B1/fr
Priority to DE8484402019T priority patent/DE3471308D1/de
Priority to PT79365A priority patent/PT79365B/fr
Priority to DK493784A priority patent/DK493784A/da
Priority to CA000465553A priority patent/CA1219261A/fr
Priority to FI844069A priority patent/FI76800C/fi
Priority to IL73259A priority patent/IL73259A/xx
Priority to NO844118A priority patent/NO161738C/no
Priority to GR80671A priority patent/GR80671B/el
Priority to MX203064A priority patent/MX157033A/es
Priority to HU843864A priority patent/HUT36476A/hu
Priority to ES536786A priority patent/ES8601201A1/es
Priority to AU34270/84A priority patent/AU564510B2/en
Priority to US06/661,483 priority patent/US4567177A/en
Priority to NZ209912A priority patent/NZ209912A/en
Priority to AR29827384A priority patent/AR240700A1/es
Publication of FR2565230A1 publication Critical patent/FR2565230A1/fr
Application granted granted Critical
Publication of FR2565230B3 publication Critical patent/FR2565230B3/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8408726A 1983-10-17 1984-06-04 Derives de (1h-dihydro-4,5 imidazolyl-2)-2 hexahydro-1,2,4,5,6,7 azepino (3,2,1-hi) indole, leur preparation et leur application en therapeutique Expired FR2565230B3 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR8408726A FR2565230B3 (fr) 1984-06-04 1984-06-04 Derives de (1h-dihydro-4,5 imidazolyl-2)-2 hexahydro-1,2,4,5,6,7 azepino (3,2,1-hi) indole, leur preparation et leur application en therapeutique
EP84402019A EP0139584B1 (fr) 1983-10-17 1984-10-08 Dérivés d'imidazoline, leur préparation et leur application en thérapeutique
DE8484402019T DE3471308D1 (en) 1983-10-17 1984-10-08 Imidazoline derivatives, their preparation and therapeutical use
AT84402019T ATE34392T1 (de) 1983-10-17 1984-10-08 Imidazolinderivate, ihre herstellung und therapeutische verwendung.
NO844118A NO161738C (no) 1983-10-17 1984-10-16 Analogifremgangsm te for fremstilling av terapeutisk aktive imidazolinderivater.
CA000465553A CA1219261A (fr) 1983-10-17 1984-10-16 Derives d'imidazoline, leur preparation, et produits pharmaceutiques qui les renferment
FI844069A FI76800C (fi) 1983-10-17 1984-10-16 Foerfarande foer framstaellning av 2-(2-imidazolyl)pyrrolo/3,2-ij/kinoliner och 2-(2-imidazolyl)azepino /3,2,1-hi/indoler, vilka aer antagonister mot 2-adrenergiska receptorer.
IL73259A IL73259A (en) 1983-10-17 1984-10-16 2-(2-imidazolin-2-yl)pyrrolo(3,2,1-ij)quinoline(and azepino(3,2,1-hi)indole)derivatives and pharmaceutical compositions containing them
PT79365A PT79365B (fr) 1983-10-17 1984-10-16 Procede de preparation de derives d'imidazoline et de compositions pharmaceutiques les contenant
GR80671A GR80671B (en) 1983-10-17 1984-10-16 Process for the preparation of imidazoline derivatives
MX203064A MX157033A (es) 1983-10-17 1984-10-16 Procedimiento para preparar derivados de pirrolo quinoleina
HU843864A HUT36476A (en) 1983-10-17 1984-10-16 Process for producing imidazoline derivatives and pharmaceutical compositions containing them
ES536786A ES8601201A1 (es) 1983-10-17 1984-10-16 Procedimiento para preparar derivados de imidazolina
AU34270/84A AU564510B2 (en) 1983-10-17 1984-10-16 (4,5-dihydro-1h-imidazo-z-yl)-1,2,4,5,6,7-hexa hydroazepino (3,2,1-hi) indole derivatives
US06/661,483 US4567177A (en) 1983-10-17 1984-10-16 Imidazoline derivatives as α2 -antagonists
DK493784A DK493784A (da) 1983-10-17 1984-10-16 Imidazolinderivater og fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende saadanne forbindelser
NZ209912A NZ209912A (en) 1983-10-17 1984-10-17 Imidazoline derivatives and pharmaceutical compositions
AR29827384A AR240700A1 (es) 1983-10-17 1984-10-17 Procedimiento para preparar derivados de (imidazolil-2)-2-pirrol3,2,1-ij quinolina o de (imidazolil-2)-2-azepin3,2,1-hi-indol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8408726A FR2565230B3 (fr) 1984-06-04 1984-06-04 Derives de (1h-dihydro-4,5 imidazolyl-2)-2 hexahydro-1,2,4,5,6,7 azepino (3,2,1-hi) indole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2565230A1 FR2565230A1 (fr) 1985-12-06
FR2565230B3 true FR2565230B3 (fr) 1986-10-24

Family

ID=9304673

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8408726A Expired FR2565230B3 (fr) 1983-10-17 1984-06-04 Derives de (1h-dihydro-4,5 imidazolyl-2)-2 hexahydro-1,2,4,5,6,7 azepino (3,2,1-hi) indole, leur preparation et leur application en therapeutique

Country Status (1)

Country Link
FR (1) FR2565230B3 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1474093A4 (fr) * 2002-02-04 2005-02-16 Merck & Co Inc Inhibiteurs de granzyme b

Also Published As

Publication number Publication date
FR2565230A1 (fr) 1985-12-06

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