[go: up one dir, main page]

FR24C1017I2 - USES OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS - Google Patents

USES OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS

Info

Publication number
FR24C1017I2
FR24C1017I2 FR24C1017C FR24C1017C FR24C1017I2 FR 24C1017 I2 FR24C1017 I2 FR 24C1017I2 FR 24C1017 C FR24C1017 C FR 24C1017C FR 24C1017 C FR24C1017 C FR 24C1017C FR 24C1017 I2 FR24C1017 I2 FR 24C1017I2
Authority
FR
France
Prior art keywords
antagonists
treatment
atopic dermatitis
atopic
dermatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR24C1017C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR24C1017I1 publication Critical patent/FR24C1017I1/en
Application granted granted Critical
Publication of FR24C1017I2 publication Critical patent/FR24C1017I2/en
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR24C1017C 2016-09-23 2024-04-29 USES OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS Active FR24C1017I2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662398713P 2016-09-23 2016-09-23
US201762527204P 2017-06-30 2017-06-30
US201762530683P 2017-07-10 2017-07-10
US201762539037P 2017-07-31 2017-07-31
PCT/US2017/052891 WO2018057849A1 (en) 2016-09-23 2017-09-22 Uses of il-13 antagonists for treating atopic dermatitis

Publications (2)

Publication Number Publication Date
FR24C1017I1 FR24C1017I1 (en) 2024-06-28
FR24C1017I2 true FR24C1017I2 (en) 2024-10-25

Family

ID=60020628

Family Applications (1)

Application Number Title Priority Date Filing Date
FR24C1017C Active FR24C1017I2 (en) 2016-09-23 2024-04-29 USES OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS

Country Status (28)

Country Link
US (3) US11434286B2 (en)
EP (2) EP4268845A3 (en)
JP (1) JP6995844B2 (en)
KR (1) KR102557643B1 (en)
CN (1) CN109715201A (en)
AU (1) AU2017330405B2 (en)
CA (1) CA3031589C (en)
CY (2) CY1126255T1 (en)
DK (1) DK3528838T5 (en)
ES (1) ES2958593T3 (en)
FI (2) FI3528838T3 (en)
FR (1) FR24C1017I2 (en)
HR (1) HRP20231015T1 (en)
HU (2) HUE063135T2 (en)
IL (1) IL265473B2 (en)
LT (2) LT3528838T (en)
MX (1) MX2019002672A (en)
NL (1) NL301269I2 (en)
NZ (1) NZ790629A (en)
PL (1) PL3528838T3 (en)
PT (1) PT3528838T (en)
RS (1) RS64550B1 (en)
RU (1) RU2752785C2 (en)
SG (1) SG11201900845YA (en)
SI (1) SI3528838T1 (en)
TW (1) TWI787203B (en)
UA (1) UA124269C2 (en)
WO (1) WO2018057849A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3448391T3 (en) 2016-04-27 2024-09-16 AbbVie Manufacturing Management Unlimited Company Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies
RU2752785C2 (en) * 2016-09-23 2021-08-04 Дженентек, Инк. Use of il-13 antagonists for the treatment of atopic dermatitis
WO2021191220A1 (en) * 2020-03-23 2021-09-30 Medimmune Limited Methods for treating atopic dermatitis and related disorders
US12187788B2 (en) * 2020-03-23 2025-01-07 Medimmune Limited Methods for treating atopic dermatitis and related disorders
US20230383001A1 (en) * 2020-10-09 2023-11-30 Kyowa Kirin Co., Ltd. Method for treating ox40 related disease
IL305901A (en) 2021-03-17 2023-11-01 Receptos Llc Methods of treating atopic dermatitis with anti il-13 antibodies
TWI847170B (en) * 2021-07-16 2024-07-01 美商德米拉股份有限公司 Il-13 antibodies for the treatment of atopic dermatitis
TWI859566B (en) * 2021-08-13 2024-10-21 美商德米拉股份有限公司 Il-13 antibodies for the treatment of atopic dermatitis
CN118076636A (en) * 2021-09-15 2024-05-24 德米拉公司 IL-13 inhibitors for the treatment of prurigo nodularis
KR20250039317A (en) * 2022-05-05 2025-03-20 더미라, 인코포레이티드 IL-13 antibodies for the treatment of atopic dermatitis
CR20250009A (en) 2022-06-17 2025-05-07 Apogee Biologics Inc ANTIBODIES THAT BIND TO INTERLEUKIN 13 AND METHODS OF USE
CN120077070A (en) * 2022-09-06 2025-05-30 亚狮康私人有限公司 Treatment of sleep loss or sleep disorders in dermatitis patients
KR102773781B1 (en) 2023-03-14 2025-02-28 주식회사 지오비스타 Antibodies that specifically bind to interleukin-13 and uses thereof
CN120858113A (en) 2023-03-14 2025-10-28 吉奥维斯塔有限公司 Antibodies specifically binding to interleukin-13 and uses thereof
GB202306662D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Dosage regimen
KR20250017610A (en) 2023-07-27 2025-02-04 김천균 Composition for treatment and prevention of atpoy, and its manufacture method
TW202525846A (en) 2023-08-25 2025-07-01 美商普羅特歐拉吉克適美國公司 Anti-il-13 multispecific antibody constructs and uses thereof
US20250230251A1 (en) 2023-12-20 2025-07-17 Bristol-Myers Squibb Company Antibodies targeting il-18 receptor beta (il-18rb) and related methods
WO2025155874A1 (en) * 2024-01-18 2025-07-24 Enveda Therapeutics, Inc. Methods and compounds for modulating immune response

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US6548640B1 (en) 1986-03-27 2003-04-15 Btg International Limited Altered antibodies
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
DE3883899T3 (en) 1987-03-18 1999-04-22 Sb2, Inc., Danville, Calif. CHANGED ANTIBODIES.
ATE102631T1 (en) 1988-11-11 1994-03-15 Medical Res Council CLONING OF IMMUNOGLOBULIN SEQUENCES FROM THE VARIABLE DOMAINS.
DE3920358A1 (en) 1989-06-22 1991-01-17 Behringwerke Ag BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
EP0940468A1 (en) 1991-06-14 1999-09-08 Genentech, Inc. Humanized antibody variable domain
GB9114948D0 (en) 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
EP0604580A1 (en) 1991-09-19 1994-07-06 Genentech, Inc. EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab') 2? ANTIBODIES
FI941572A7 (en) 1991-10-07 1994-05-27 Oncologix Inc Combination and method of use of anti-erbB-2 monoclonal antibodies
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
DE69334255D1 (en) 1992-02-06 2009-02-12 Novartis Vaccines & Diagnostic Marker for cancer and biosynthetic binding protein for it
WO1994029351A2 (en) 1993-06-16 1994-12-22 Celltech Limited Antibodies
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5840523A (en) 1995-03-01 1998-11-24 Genetech, Inc. Methods and compositions for secretion of heterologous polypeptides
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
GB9603256D0 (en) 1996-02-16 1996-04-17 Wellcome Found Antibodies
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
JP2002506353A (en) 1997-06-24 2002-02-26 ジェネンテック・インコーポレーテッド Methods and compositions for galactosylated glycoproteins
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
WO1999022764A1 (en) 1997-10-31 1999-05-14 Genentech, Inc. Methods and compositions comprising glycoprotein glycoforms
US6610833B1 (en) 1997-11-24 2003-08-26 The Institute For Human Genetics And Biochemistry Monoclonal human natural antibodies
BR9813365A (en) 1997-12-05 2004-06-15 Scripps Research Inst Method for Production and Humanization of a Mouse Monoclonal Antibody
PT1068241E (en) 1998-04-02 2007-11-19 Genentech Inc Antibody variants and fragments thereof
US6194551B1 (en) 1998-04-02 2001-02-27 Genentech, Inc. Polypeptide variants
DK1071700T3 (en) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glycosylation modification of antibodies to enhance antibody-dependent cellular cytotoxicity
US20030175884A1 (en) 2001-08-03 2003-09-18 Pablo Umana Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
KR101077001B1 (en) 1999-01-15 2011-10-26 제넨테크, 인크. Polypeptide Variants with Altered Effector Function
AU3672800A (en) 1999-04-09 2000-11-14 Kyowa Hakko Kogyo Co. Ltd. Method for controlling the activity of immunologically functional molecule
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
DE60022369T2 (en) 1999-10-04 2006-05-18 Medicago Inc., Sainte Foy PROCESS FOR REGULATING THE TRANSCRIPTION OF FOREIGN GENES IN THE PRESENCE OF NITROGEN
EP1229125A4 (en) 1999-10-19 2005-06-01 Kyowa Hakko Kogyo Kk PROCESS FOR PRODUCING A POLYPEPTIDE
CA2393869A1 (en) 1999-12-15 2001-06-21 Genetech,Inc. Shotgun scanning, a combinatorial method for mapping functional protein epitopes
MXPA02010011A (en) 2000-04-11 2003-04-25 Genentech Inc Multivalent antibodies and uses therefor.
US7064191B2 (en) 2000-10-06 2006-06-20 Kyowa Hakko Kogyo Co., Ltd. Process for purifying antibody
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
HU231090B1 (en) 2000-10-06 2020-07-28 Kyowa Kirin Co., Ltd. Cells producing antibody compositions
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
ES2405944T3 (en) 2000-11-30 2013-06-04 Medarex, Inc. Nucleic acids encoding reorganized human immunoglobulin sequences from transgenic transchromosomal mice zadas
ATE430580T1 (en) 2001-10-25 2009-05-15 Genentech Inc GLYCOPROTEIN COMPOSITIONS
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
WO2003085102A1 (en) 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Cell with depression or deletion of the activity of protein participating in gdp-fucose transport
CA2481837A1 (en) 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Production process for antibody composition
EP1498485A4 (en) 2002-04-09 2006-09-06 Kyowa Hakko Kogyo Kk CELLS WITH MODIFIED GENOM
WO2003084569A1 (en) 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Drug containing antibody composition
JP4832719B2 (en) 2002-04-09 2011-12-07 協和発酵キリン株式会社 Medicine containing antibody composition for FcγRIIIa polymorphism patients
EP1498491A4 (en) 2002-04-09 2006-12-13 Kyowa Hakko Kogyo Kk METHOD FOR INCREASING THE ACTIVITY OF AN ANTIBODY COMPOSITION FOR BINDING TO THE FC GAMMA RECEPTOR IIIA
CA2488441C (en) 2002-06-03 2015-01-27 Genentech, Inc. Synthetic antibody phage libraries
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
CN103833854B (en) 2002-12-16 2017-12-12 健泰科生物技术公司 Immunoglobulin variants and application thereof
US20050079574A1 (en) 2003-01-16 2005-04-14 Genentech, Inc. Synthetic antibody phage libraries
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
CA2542046A1 (en) 2003-10-08 2005-04-21 Kyowa Hakko Kogyo Co., Ltd. Fused protein composition
EP1705251A4 (en) 2003-10-09 2009-10-28 Kyowa Hakko Kirin Co Ltd PROCESS FOR PREPARING ANTIBODY COMPOSITION USING THE FUNCTION OF A1,6-FUCOSYLTRANSFERASE HEMOMING RNA
BRPI0416262B1 (en) 2003-11-05 2022-04-12 Roche Glycart Ag Humanized type II anti-human cd20 antibody, its production method, its uses, as well as isolated polynucleotide, expression vector and pharmaceutical composition
JPWO2005053742A1 (en) 2003-12-04 2007-06-28 協和醗酵工業株式会社 Medicament containing antibody composition
ES2775204T3 (en) * 2003-12-23 2020-07-24 Genentech Inc Novel anti-IL13 antibodies and uses thereof
MXPA06011199A (en) 2004-03-31 2007-04-16 Genentech Inc Humanized anti-tgf-beta antibodies.
US7785903B2 (en) 2004-04-09 2010-08-31 Genentech, Inc. Variable domain library and uses
WO2005100402A1 (en) 2004-04-13 2005-10-27 F.Hoffmann-La Roche Ag Anti-p-selectin antibodies
US20070048785A1 (en) 2004-06-09 2007-03-01 Lin Laura L Anti-IL-13 antibodies and complexes
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
AR049390A1 (en) 2004-06-09 2006-07-26 Wyeth Corp ANTIBODIES AGAINST HUMAN INTERLEUQUINE-13 AND USES OF THE SAME
TWI309240B (en) 2004-09-17 2009-05-01 Hoffmann La Roche Anti-ox40l antibodies
CN101065151B (en) 2004-09-23 2014-12-10 健泰科生物技术公司 Cysteine engineered antibodies and conjugates
JO3000B1 (en) 2004-10-20 2016-09-05 Genentech Inc Antibody Formulations.
CN101119761B (en) 2004-11-24 2010-08-18 Shl医药公司 Injection device
EP1885414B1 (en) 2005-06-01 2012-11-21 SHL Group AB Device for delivering medicament
US20060276753A1 (en) 2005-06-01 2006-12-07 Victor Kronestedt Device for delivering medicament
WO2007036745A2 (en) 2005-09-30 2007-04-05 Medimmune Limited Interleukin-13 antibody composition
JP5006330B2 (en) * 2005-10-21 2012-08-22 ノバルティス アーゲー Human antibodies against IL13 and therapeutic uses
WO2007056441A2 (en) 2005-11-07 2007-05-18 Genentech, Inc. Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
WO2007064919A2 (en) 2005-12-02 2007-06-07 Genentech, Inc. Binding polypeptides with restricted diversity sequences
AR060871A1 (en) 2006-05-09 2008-07-16 Genentech Inc UNION OF POLYPEPTIDES WITH OPTIMIZED SUPERCONTIGES
US10118970B2 (en) 2006-08-30 2018-11-06 Genentech, Inc. Multispecific antibodies
US20080226635A1 (en) 2006-12-22 2008-09-18 Hans Koll Antibodies against insulin-like growth factor I receptor and uses thereof
CL2008000058A1 (en) 2007-01-09 2008-05-23 Wyeth Corp FORMULATION THAT INCLUDES AN ANTI-IL13 ANTIBODY, A CRIPROTECTOR, AND A DAMPING SOLUTION; PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT; METHOD TO TREAT AN IL13-RELATED DISORDER; AND PHARMACEUTICAL FORMS THAT UNDERSTAND IT.
CN100592373C (en) 2007-05-25 2010-02-24 群康科技(深圳)有限公司 Liquid crystal display panel driving device and driving method thereof
ES2563027T3 (en) 2008-01-07 2016-03-10 Amgen Inc. Method for manufacturing antibody Fc heterodimer molecules using electrostatic conduction effects
FR2944448B1 (en) 2008-12-23 2012-01-13 Adocia STABLE PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE MONODONAL ANTIBODY AND AT LEAST ONE AMPHIPHILIC POLYSACHARIDE COMPRISING SUBSTITUENTS DERIVED FROM HYDROFOB ALCOHOLS OR HYDROPHOBIC AMINES.
AU2013204902B2 (en) * 2010-12-16 2016-11-10 Genentech, Inc. Diagnosis and treatments relating to TH2 inhibition
WO2012083132A2 (en) * 2010-12-16 2012-06-21 Genentech, Inc. Diagnosis and treatments relating to th2 inhibition
EP2720736B1 (en) 2011-06-17 2019-01-16 SHL Group AB Injection device
KR101566132B1 (en) 2011-06-17 2015-11-04 에스에이치엘 그룹 에이비 Injection device
KR102259829B1 (en) * 2011-10-31 2021-06-03 제넨테크, 인크. Antibody formulations
ES2981062T3 (en) 2012-09-07 2024-10-07 Regeneron Pharma Methods for the treatment of atopic dermatitis by administering an IL-4R antagonist
MX2015013901A (en) 2013-04-05 2015-12-11 Genentech Inc Anti-il-4 antibodies and bispecific antibodies and uses thereof.
AU2015209124A1 (en) * 2014-01-27 2016-08-18 Medimmune, Llc Dipeptidyl peptidase-4 (DPP4/CD26) as a peripheral biomarker of IL-13 activation in asthmatic lung
JP2018511797A (en) * 2015-03-16 2018-04-26 ジェネンテック, インコーポレイテッド IL-13 detection and quantification method and use in diagnosis and treatment of Th2-related diseases
RU2752785C2 (en) * 2016-09-23 2021-08-04 Дженентек, Инк. Use of il-13 antagonists for the treatment of atopic dermatitis

Also Published As

Publication number Publication date
FIC20240013I1 (en) 2024-04-30
FI3528838T3 (en) 2023-10-02
EP4268845A3 (en) 2024-02-28
HUS2400011I1 (en) 2024-06-28
US20240228606A1 (en) 2024-07-11
CY1126255T1 (en) 2025-05-09
EP3528838A1 (en) 2019-08-28
NZ790629A (en) 2025-11-28
LTC3528838I2 (en) 2025-10-10
CY2024013I2 (en) 2025-05-09
US20190270803A1 (en) 2019-09-05
NL301269I2 (en) 2024-05-22
IL265473B2 (en) 2024-01-01
LT3528838T (en) 2023-10-10
HUE063135T2 (en) 2023-12-28
TWI787203B (en) 2022-12-21
EP4268845A2 (en) 2023-11-01
RU2019103943A3 (en) 2020-12-29
PL3528838T3 (en) 2023-12-18
TW201815415A (en) 2018-05-01
KR20190053184A (en) 2019-05-17
FR24C1017I1 (en) 2024-06-28
IL265473A (en) 2019-05-30
WO2018057849A1 (en) 2018-03-29
NZ750179A (en) 2025-03-28
ES2958593T3 (en) 2024-02-12
PT3528838T (en) 2023-09-04
IL265473B1 (en) 2023-09-01
KR102557643B1 (en) 2023-07-20
RU2019103943A (en) 2020-10-23
CA3031589A1 (en) 2018-03-29
DK3528838T5 (en) 2024-09-02
JP2019533646A (en) 2019-11-21
CA3031589C (en) 2025-05-06
US20220372131A1 (en) 2022-11-24
LTPA2024512I1 (en) 2024-05-27
AU2017330405A1 (en) 2019-02-21
EP3528838B1 (en) 2023-07-19
JP6995844B2 (en) 2022-02-04
SI3528838T1 (en) 2023-10-30
DK3528838T3 (en) 2023-08-28
AU2017330405B2 (en) 2024-02-01
UA124269C2 (en) 2021-08-18
CN109715201A (en) 2019-05-03
HRP20231015T1 (en) 2023-12-08
US11434286B2 (en) 2022-09-06
MX2019002672A (en) 2019-07-04
CY2024013I1 (en) 2025-05-09
RU2752785C2 (en) 2021-08-04
SG11201900845YA (en) 2019-02-27
RS64550B1 (en) 2023-09-29

Similar Documents

Publication Publication Date Title
FR24C1017I2 (en) USES OF IL-13 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DERMATITIS
MA47719A (en) ESKETAMINE FOR THE TREATMENT OF DEPRESSION
EP3448875A4 (en) COMPOSITIONS FOR THE TREATMENT OF DISEASES
MA42439A (en) AGENTS, USES AND METHODS FOR THE TREATMENT OF SYNUCLEINOPATHY
MA46836A (en) AGENTS, USES AND METHODS FOR THE TREATMENT OF SYNUCLEINOPATHY
EP3359074A4 (en) ELECTROPORATION FOR THE TREATMENT OF OBESITY OR DIABETES
EP3328376A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF METABOLIC REPROGRAMMING DISORDERS
EP3370703A4 (en) COMBINATION OF GEMCABEN FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
EP3340982A4 (en) COMPOUNDS FOR THE TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS
MA39748A (en) CENICRIVIROC FOR THE TREATMENT OF FIBROSIS
EP3298140A4 (en) COMPOSITIONS FOR THE TREATMENT OF PATHOLOGICAL CALCIFICATION STATES, AND METHODS USING THE SAME
EP3325963A4 (en) IMPROVING THE ESTIMATION OF GLOBULES
EP3328374A4 (en) GLUTAMINE ANTAGONISTS FOR THE TREATMENT OF COGNITIVE DEFICITS
EP3390642A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF PIGMENT RETINITY 18 AND PIGMENT RETINITY 13
EP3405191A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF HYPERHIDROSIS
EP3458079A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACNE
EP3344325A4 (en) LOCAL ADMINISTRATION OF MEDICINES FOR THE TREATMENT OF ASTHMA
EP3334432A4 (en) CERDULATINIB FOR THE TREATMENT OF MYELOMA
MA42953A (en) COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS
EP3541379A4 (en) COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION
EP3579837C0 (en) AXITINIB, NINTEDANIB OR LENVATINIB FOR THE TREATMENT OF ROSACEA AND ATOPIC DERMATITIS
EP3347032A4 (en) TREATMENT OF ASCITE
EP3349793A4 (en) ANTI-S100A8 FOR THE TREATMENT OF LEUKEMIA
EP3331545A4 (en) SPECIFIC AGENTS OF THE EXTRACELLULAR DOMAIN OF HEMICANAL FOR THE TREATMENT OF SEPTICEMIA
EP3344650A4 (en) AAV-EPO FOR THE TREATMENT OF PETS