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FR2434158A1 - NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS - Google Patents

NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Info

Publication number
FR2434158A1
FR2434158A1 FR7824674A FR7824674A FR2434158A1 FR 2434158 A1 FR2434158 A1 FR 2434158A1 FR 7824674 A FR7824674 A FR 7824674A FR 7824674 A FR7824674 A FR 7824674A FR 2434158 A1 FR2434158 A1 FR 2434158A1
Authority
FR
France
Prior art keywords
benzoxazine
medicaments
preparation
application
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7824674A
Other languages
French (fr)
Other versions
FR2434158B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Productos Esteve Internacional Prodesin SA
Original Assignee
Productos Esteve Internacional Prodesin SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Productos Esteve Internacional Prodesin SA filed Critical Productos Esteve Internacional Prodesin SA
Priority to FR7824674A priority Critical patent/FR2434158A1/en
Priority to ES481856A priority patent/ES481856A1/en
Priority to DD79215096A priority patent/DD145534A5/en
Priority to HU79PO694A priority patent/HU182916B/en
Priority to PL1979217893A priority patent/PL116771B1/en
Priority to CA334,287A priority patent/CA1128511A/en
Priority to GB7929266A priority patent/GB2031410B/en
Priority to RO7998518A priority patent/RO78156A/en
Priority to BG044725A priority patent/BG30929A3/en
Priority to GR52886A priority patent/GR69619B/el
Priority to SU792804596A priority patent/SU797576A3/en
Priority to DE19792934166 priority patent/DE2934166A1/en
Priority to PT70107A priority patent/PT70107A/en
Priority to JP10764779A priority patent/JPS5533484A/en
Priority to AR277829A priority patent/AR222494A1/en
Priority to AT0568379A priority patent/AT373591B/en
Priority to YU2073/79A priority patent/YU40849B/en
Priority to IL58096A priority patent/IL58096A/en
Priority to BE0/196852A priority patent/BE878395A/en
Priority to FI792632A priority patent/FI68818C/en
Priority to CS795769A priority patent/CS208131B2/en
Priority to SE7907067A priority patent/SE446865B/en
Priority to NL7906408A priority patent/NL7906408A/en
Priority to CH773579A priority patent/CH643548A5/en
Priority to EG520/79A priority patent/EG14355A/en
Publication of FR2434158A1 publication Critical patent/FR2434158A1/en
Application granted granted Critical
Publication of FR2434158B1 publication Critical patent/FR2434158B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La présente invention concerne de nouveaux dérivés de 1,3-benzoxazine-2,4-dione, leur préparation et leur application en tant que médicaments. Les dérivés selon l'invention répondent à la formule générale :The present invention relates to novel derivatives of 1,3-benzoxazine-2,4-dione, their preparation and their application as medicaments. The derivatives according to the invention correspond to the general formula:

FR7824674A 1978-08-25 1978-08-25 NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS Granted FR2434158A1 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR7824674A FR2434158A1 (en) 1978-08-25 1978-08-25 NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
ES481856A ES481856A1 (en) 1978-08-25 1979-06-06 New derivatives of 1,3- benzoxazine-2,4-dione, their preparation and their application as medicaments
DD79215096A DD145534A5 (en) 1978-08-25 1979-08-21 PROCESS FOR THE PREPARATION OF 1,3-BENZOXAZINE-2,4-DION DERIVATIVES
PL1979217893A PL116771B1 (en) 1978-08-25 1979-08-22 Process for preparing novel derivatives of 1,3-benzoxazynodi-2,4-one
CA334,287A CA1128511A (en) 1978-08-25 1979-08-22 Preparation and pharmaceutical applications of 1,3-benzoxazine-2,4-dione derivatives
GB7929266A GB2031410B (en) 1978-08-25 1979-08-22 Derivatives of 1,3 benzoxazine 2,4 dione,their preparation and their application as medicants
RO7998518A RO78156A (en) 1978-08-25 1979-08-22 PROCESS FOR PREPARATION OF 1,3-BENZOXOZINE-2,4-DIONE DERIVATIVES
BG044725A BG30929A3 (en) 1978-08-25 1979-08-22 METHOD FOR OBTAINING 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES
GR52886A GR69619B (en) 1978-08-25 1979-08-22
HU79PO694A HU182916B (en) 1978-08-25 1979-08-22 Process for preparing 1,3-benzoxazine-2,4-dione derivatives
FI792632A FI68818C (en) 1978-08-25 1979-08-23 REFERENCE TO A FRAMEWORK FOR THERAPEUTIC TREATMENT OF 1,3-BENZOZAZINE-2,4-DIONER
PT70107A PT70107A (en) 1978-08-25 1979-08-23 PROCESS FOR PREPARING NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
SU792804596A SU797576A3 (en) 1978-08-25 1979-08-23 Method of preparing 1,3-benzoxazin-2,4-dione derivatives
AR277829A AR222494A1 (en) 1978-08-25 1979-08-23 PROCEDURE FOR THE PREPARATION OF NEW 1,3-BENZOXACIN-2,4-DIONA DERIVATIVES WITH ANALGESIC ACTIVITY
AT0568379A AT373591B (en) 1978-08-25 1979-08-23 METHOD FOR PRODUCING NEW 1,3-BENZOXAZINE-2,4-DION DERIVATIVES
YU2073/79A YU40849B (en) 1978-08-25 1979-08-23 Process for obtaining 1,3-benzoxazine-2,4-dione derivatives
IL58096A IL58096A (en) 1978-08-25 1979-08-23 1,3-benzoxazine-2,4-dione derivatives,their preparation and pharmaceutical compositions containing them
BE0/196852A BE878395A (en) 1978-08-25 1979-08-23 NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
DE19792934166 DE2934166A1 (en) 1978-08-25 1979-08-23 1,3-BENZOXAZINE-2,4-DION DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
JP10764779A JPS5533484A (en) 1978-08-25 1979-08-23 1*33benzoxazinee2*44dione derivative*its manufacture and medical composition
CS795769A CS208131B2 (en) 1978-08-25 1979-08-24 Method of making the new derivatives of the 1,3-benzoxazine-2,4-dione
SE7907067A SE446865B (en) 1978-08-25 1979-08-24 NEW DERIVATIVES OF 1,3-BENZOXAZINE-2,4-DION, PROCEDURE FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITIONS
NL7906408A NL7906408A (en) 1978-08-25 1979-08-24 NEW 1,3-BENZOXAZINE-2,4-DION DERIVATIVES, THEIR PREPARATIONS AND MEDICINAL PRODUCTS WITH THESE SUBSTANCES AS THE ACTIVE INGREDIENT.
CH773579A CH643548A5 (en) 1978-08-25 1979-08-24 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM
EG520/79A EG14355A (en) 1978-08-25 1979-08-27 Procede pour la preparation de nouveaux derives de 1,3-benzoxazine-2,4 dione et leur application en tant que medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7824674A FR2434158A1 (en) 1978-08-25 1978-08-25 NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Publications (2)

Publication Number Publication Date
FR2434158A1 true FR2434158A1 (en) 1980-03-21
FR2434158B1 FR2434158B1 (en) 1985-05-03

Family

ID=9212085

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7824674A Granted FR2434158A1 (en) 1978-08-25 1978-08-25 NOVEL 1,3-BENZOXAZINE-2,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Country Status (25)

Country Link
JP (1) JPS5533484A (en)
AR (1) AR222494A1 (en)
AT (1) AT373591B (en)
BE (1) BE878395A (en)
BG (1) BG30929A3 (en)
CA (1) CA1128511A (en)
CH (1) CH643548A5 (en)
CS (1) CS208131B2 (en)
DD (1) DD145534A5 (en)
DE (1) DE2934166A1 (en)
EG (1) EG14355A (en)
ES (1) ES481856A1 (en)
FI (1) FI68818C (en)
FR (1) FR2434158A1 (en)
GB (1) GB2031410B (en)
GR (1) GR69619B (en)
HU (1) HU182916B (en)
IL (1) IL58096A (en)
NL (1) NL7906408A (en)
PL (1) PL116771B1 (en)
PT (1) PT70107A (en)
RO (1) RO78156A (en)
SE (1) SE446865B (en)
SU (1) SU797576A3 (en)
YU (1) YU40849B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA82827C2 (en) 2000-12-18 2008-05-26 Inhibitors against the production and release of inflammatory cytokines
US20060122243A1 (en) 2002-06-06 2006-06-08 Susumu Muto Antiallergic
JP4743382B2 (en) * 2002-06-06 2011-08-10 株式会社医薬分子設計研究所 O-substituted hydroxyaryl derivatives
CN108658887B (en) * 2018-06-20 2022-04-05 中南大学 Benzo[d][1,3]oxazine-2,4(1H)-dione derivatives and their synthetic methods and uses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR968834A (en) * 1946-10-01 1950-12-06 Gen Aniline & Film Corp Process for the preparation of oxazines-diones and production of aromatic amides 1-hydroxy-2 acids from these oxazines diones
FR1490492A (en) * 1965-01-25 1967-08-04 Robapharm A G New basic derivatives of benzoxazine and their preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1153375B (en) * 1960-05-25 1963-08-29 Thomae Gmbh Dr K Process for the preparation of benzoxazine- (1, 3) -dione- (2, 4)
GB1069367A (en) * 1964-10-01 1967-05-17 Aspro Nicholas Ltd Improvements in or relating to the production of 1:3-benzoxazine-2:4-dione

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR968834A (en) * 1946-10-01 1950-12-06 Gen Aniline & Film Corp Process for the preparation of oxazines-diones and production of aromatic amides 1-hydroxy-2 acids from these oxazines diones
FR1490492A (en) * 1965-01-25 1967-08-04 Robapharm A G New basic derivatives of benzoxazine and their preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1974 *

Also Published As

Publication number Publication date
CA1128511A (en) 1982-07-27
SE446865B (en) 1986-10-13
DD145534A5 (en) 1980-12-17
PL217893A1 (en) 1980-04-21
FI68818B (en) 1985-07-31
SU797576A3 (en) 1981-01-15
IL58096A0 (en) 1979-12-30
AT373591B (en) 1984-02-10
CH643548A5 (en) 1984-06-15
SE7907067L (en) 1980-02-26
FI792632A7 (en) 1980-02-26
EG14355A (en) 1983-12-31
YU40849B (en) 1986-06-30
BG30929A3 (en) 1981-09-15
ATA568379A (en) 1983-06-15
GR69619B (en) 1982-07-06
AR222494A1 (en) 1981-05-29
GB2031410A (en) 1980-04-23
RO78156A (en) 1982-02-01
NL7906408A (en) 1980-02-27
JPS5533484A (en) 1980-03-08
HU182916B (en) 1984-03-28
DE2934166A1 (en) 1980-02-28
IL58096A (en) 1982-12-31
FR2434158B1 (en) 1985-05-03
YU207379A (en) 1983-02-28
PT70107A (en) 1979-09-01
BE878395A (en) 1980-02-25
FI68818C (en) 1985-11-11
PL116771B1 (en) 1981-06-30
CS208131B2 (en) 1981-08-31
ES481856A1 (en) 1980-02-16
GB2031410B (en) 1982-12-01

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