FR2430945A2 - Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays - Google Patents
Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol spraysInfo
- Publication number
- FR2430945A2 FR2430945A2 FR7820878A FR7820878A FR2430945A2 FR 2430945 A2 FR2430945 A2 FR 2430945A2 FR 7820878 A FR7820878 A FR 7820878A FR 7820878 A FR7820878 A FR 7820878A FR 2430945 A2 FR2430945 A2 FR 2430945A2
- Authority
- FR
- France
- Prior art keywords
- thenoyl
- cysteine
- bronchitic
- derivs
- admin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000443 aerosol Substances 0.000 title 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 title 1
- 235000018417 cysteine Nutrition 0.000 title 1
- 239000007921 spray Substances 0.000 title 1
- 239000004201 L-cysteine Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
N-(alpha-thenoyl)-L-cysteines of formula (I) are new (where R is H or 1-8C alkyl, R1 is alpha-thenoyl or carboxymethyl). Specifically claimed are N,S-di-(alpha-thenoyl)-L-cysteine methyl ester and S-carboxymethyl-N-(alpha-thenoyl)-L-cysteine. The cpds. (I) are active against bronchitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7820878A FR2430945A2 (en) | 1978-07-12 | 1978-07-12 | Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7820878A FR2430945A2 (en) | 1978-07-12 | 1978-07-12 | Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2430945A2 true FR2430945A2 (en) | 1980-02-08 |
Family
ID=9210690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7820878A Pending FR2430945A2 (en) | 1978-07-12 | 1978-07-12 | Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2430945A2 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2505329A1 (en) * | 1981-05-11 | 1982-11-12 | Sigma Tau Ind Farmaceuti | 2-METHOXYPHENYL ESTERS OF N-SUBSTITUTED AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
| FR2549057A1 (en) * | 1983-05-30 | 1985-01-18 | Pavese Ist Biochim | S-Carboxymethylcysteine derivatives having a therapeutic activity, process for their preparation and pharmaceutical compositions which contain them |
| US6974800B1 (en) | 1999-05-03 | 2005-12-13 | Astrazeneca Ab | Formulations comprising an inhibitor of carboxypeptidase U and A thrombin inhibitor |
| US7071175B1 (en) | 1999-05-03 | 2006-07-04 | Astrazeneca Ab | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2266502A1 (en) * | 1974-04-08 | 1975-10-31 | Synpharm Sa | N-(2-thenoyl)-cysteine and esters - with mucolytic activity, prepd. from cysteine (esters) and thenoyl chloride |
| FR2338701A1 (en) * | 1976-01-23 | 1977-08-19 | Blum Jean | NEW DERIVATIVES OF CYSTEINE |
-
1978
- 1978-07-12 FR FR7820878A patent/FR2430945A2/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2266502A1 (en) * | 1974-04-08 | 1975-10-31 | Synpharm Sa | N-(2-thenoyl)-cysteine and esters - with mucolytic activity, prepd. from cysteine (esters) and thenoyl chloride |
| FR2338701A1 (en) * | 1976-01-23 | 1977-08-19 | Blum Jean | NEW DERIVATIVES OF CYSTEINE |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2505329A1 (en) * | 1981-05-11 | 1982-11-12 | Sigma Tau Ind Farmaceuti | 2-METHOXYPHENYL ESTERS OF N-SUBSTITUTED AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
| FR2549057A1 (en) * | 1983-05-30 | 1985-01-18 | Pavese Ist Biochim | S-Carboxymethylcysteine derivatives having a therapeutic activity, process for their preparation and pharmaceutical compositions which contain them |
| US6974800B1 (en) | 1999-05-03 | 2005-12-13 | Astrazeneca Ab | Formulations comprising an inhibitor of carboxypeptidase U and A thrombin inhibitor |
| US7071175B1 (en) | 1999-05-03 | 2006-07-04 | Astrazeneca Ab | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BG33581A3 (en) | Herbicide means | |
| AR241528A1 (en) | Alkylsulfonamidophenylalkylamines | |
| IE781658L (en) | Derivatives of glycerol and propanediols | |
| IE44749L (en) | Cyclopeptide | |
| JPS5439098A (en) | Mitomycin c derivatives | |
| IE43970L (en) | 2-aroyl-3-phenyl-benzothiophene derivatives | |
| JPS5331676A (en) | Uracil derivatives and their preparation | |
| FR2430945A2 (en) | Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays | |
| GB1531946A (en) | Cyclopentane derivatives useful as perfuming agents | |
| JPS5283380A (en) | Synthesis of thiocarbostyril derivatives | |
| ES447307A1 (en) | Novel process for the preparation of 1-N-(alpha-substituted-omega-aminoacyl)-3{40 -deoxyribostamycin | |
| JPS52130822A (en) | Tetrachloronaphthalic imide derivative and its production | |
| JPS5417947A (en) | Spray coating of aqueous coating compound | |
| JPS5424862A (en) | Norbornane and norbornene derivatives | |
| JPS5427564A (en) | 1-branched alkylcarbonyl-3-(3,5-dihalogenophenyl) hydantoins, their preparation, and bactericides for pomicultural and horticultural uses containing the same as active agent. | |
| JPS5231051A (en) | Preparation of amino sugar derivatives | |
| JPS5384987A (en) | Cephalosporin-analogous antibiotics | |
| SE7809127L (en) | ALONE MINER | |
| JPS5334798A (en) | Furoindole derivatives | |
| JPS527956A (en) | Succinimide derivatives and its preparation | |
| JPS5246067A (en) | Reduction of optically active 5-oxo-2-pyrrolidinacetic acid esters | |
| JPS5283533A (en) | 6-substituted naphtehalene-2-oxyalkylamines | |
| JPS52102247A (en) | Novel phenylalanine derivatives | |
| JPS5217489A (en) | Preparation of penicillins and cephlosporins | |
| IE43611L (en) | Antihypertonic agent |