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FR2430945A2 - Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays - Google Patents

Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays

Info

Publication number
FR2430945A2
FR2430945A2 FR7820878A FR7820878A FR2430945A2 FR 2430945 A2 FR2430945 A2 FR 2430945A2 FR 7820878 A FR7820878 A FR 7820878A FR 7820878 A FR7820878 A FR 7820878A FR 2430945 A2 FR2430945 A2 FR 2430945A2
Authority
FR
France
Prior art keywords
thenoyl
cysteine
bronchitic
derivs
admin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7820878A
Other languages
French (fr)
Inventor
Le Hao Dong
Claude Coquelet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Chauvin SAS
Original Assignee
Laboratoires Chauvin Blache SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Chauvin Blache SA filed Critical Laboratoires Chauvin Blache SA
Priority to FR7820878A priority Critical patent/FR2430945A2/en
Publication of FR2430945A2 publication Critical patent/FR2430945A2/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

N-(alpha-thenoyl)-L-cysteines of formula (I) are new (where R is H or 1-8C alkyl, R1 is alpha-thenoyl or carboxymethyl). Specifically claimed are N,S-di-(alpha-thenoyl)-L-cysteine methyl ester and S-carboxymethyl-N-(alpha-thenoyl)-L-cysteine. The cpds. (I) are active against bronchitis.
FR7820878A 1978-07-12 1978-07-12 Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays Pending FR2430945A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7820878A FR2430945A2 (en) 1978-07-12 1978-07-12 Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7820878A FR2430945A2 (en) 1978-07-12 1978-07-12 Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays

Publications (1)

Publication Number Publication Date
FR2430945A2 true FR2430945A2 (en) 1980-02-08

Family

ID=9210690

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7820878A Pending FR2430945A2 (en) 1978-07-12 1978-07-12 Anti-bronchitic N-thenoyl derivs. of cysteine - for admin. orally or as aerosol sprays

Country Status (1)

Country Link
FR (1) FR2430945A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505329A1 (en) * 1981-05-11 1982-11-12 Sigma Tau Ind Farmaceuti 2-METHOXYPHENYL ESTERS OF N-SUBSTITUTED AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
FR2549057A1 (en) * 1983-05-30 1985-01-18 Pavese Ist Biochim S-Carboxymethylcysteine derivatives having a therapeutic activity, process for their preparation and pharmaceutical compositions which contain them
US6974800B1 (en) 1999-05-03 2005-12-13 Astrazeneca Ab Formulations comprising an inhibitor of carboxypeptidase U and A thrombin inhibitor
US7071175B1 (en) 1999-05-03 2006-07-04 Astrazeneca Ab Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2266502A1 (en) * 1974-04-08 1975-10-31 Synpharm Sa N-(2-thenoyl)-cysteine and esters - with mucolytic activity, prepd. from cysteine (esters) and thenoyl chloride
FR2338701A1 (en) * 1976-01-23 1977-08-19 Blum Jean NEW DERIVATIVES OF CYSTEINE

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2266502A1 (en) * 1974-04-08 1975-10-31 Synpharm Sa N-(2-thenoyl)-cysteine and esters - with mucolytic activity, prepd. from cysteine (esters) and thenoyl chloride
FR2338701A1 (en) * 1976-01-23 1977-08-19 Blum Jean NEW DERIVATIVES OF CYSTEINE

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505329A1 (en) * 1981-05-11 1982-11-12 Sigma Tau Ind Farmaceuti 2-METHOXYPHENYL ESTERS OF N-SUBSTITUTED AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
FR2549057A1 (en) * 1983-05-30 1985-01-18 Pavese Ist Biochim S-Carboxymethylcysteine derivatives having a therapeutic activity, process for their preparation and pharmaceutical compositions which contain them
US6974800B1 (en) 1999-05-03 2005-12-13 Astrazeneca Ab Formulations comprising an inhibitor of carboxypeptidase U and A thrombin inhibitor
US7071175B1 (en) 1999-05-03 2006-07-04 Astrazeneca Ab Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors

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