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FR2425432A1 - Antibiotic and antifungal cerulenin derivs. - prepd. from a 5-sulphonyloxy 1,2-isopropylidene xylofuranose - Google Patents

Antibiotic and antifungal cerulenin derivs. - prepd. from a 5-sulphonyloxy 1,2-isopropylidene xylofuranose

Info

Publication number
FR2425432A1
FR2425432A1 FR7813942A FR7813942A FR2425432A1 FR 2425432 A1 FR2425432 A1 FR 2425432A1 FR 7813942 A FR7813942 A FR 7813942A FR 7813942 A FR7813942 A FR 7813942A FR 2425432 A1 FR2425432 A1 FR 2425432A1
Authority
FR
France
Prior art keywords
xylofuranose
cerulenin
sulphonyloxy
derivs
prepd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7813942A
Other languages
French (fr)
Other versions
FR2425432B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Boehringer Ingelheim
Original Assignee
Laboratoires Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Boehringer Ingelheim filed Critical Laboratoires Boehringer Ingelheim
Priority to FR7813942A priority Critical patent/FR2425432A1/en
Publication of FR2425432A1 publication Critical patent/FR2425432A1/en
Application granted granted Critical
Publication of FR2425432B1 publication Critical patent/FR2425432B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION A POUR OBJET UN PROCEDE DE FABRICATION DE COMPOSES DU TYPE CERULENINE. SELON CE PROCEDE, ON TRAITE DES LACTONES DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN RADICAL HYDROCARBONE, SATURE OU NON, ET EVENTUELLEMENT RAMIFIE A 1 A 12 ATOMES DE CARBONE, PAR AMMONOLYSE, LES COMPOSES OBTENUS ETANT MIS A REAGIR AVEC DES AGENTS D'OXYDATION APPROPRIES. L'INVENTION VISE EGALEMENT LES COMPOSES NOUVEAUX AINSI OBTENUS.THE SUBJECT OF THE INVENTION IS A PROCESS FOR MANUFACTURING COMPOUNDS OF THE CERULENINE TYPE. ACCORDING TO THIS PROCESS, WE TREAT LACTONS OF GENERAL FORMULA: (CF DRAWING IN BOPI) IN WHICH R REPRESENTS A HYDROCARBON RADICAL, SATURATED OR NOT, AND POSSIBLY BRANCHED TO 1 TO 12 CARBON ATOMS, BY AMMONOLYSIS, THE COMPONENTS OBTAINED REACT WITH APPROPRIATE OXIDIZING AGENTS. THE INVENTION ALSO AIMS AT THE NEW COMPOUNDS SO OBTAINED.

FR7813942A 1978-05-10 1978-05-10 Antibiotic and antifungal cerulenin derivs. - prepd. from a 5-sulphonyloxy 1,2-isopropylidene xylofuranose Granted FR2425432A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7813942A FR2425432A1 (en) 1978-05-10 1978-05-10 Antibiotic and antifungal cerulenin derivs. - prepd. from a 5-sulphonyloxy 1,2-isopropylidene xylofuranose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7813942A FR2425432A1 (en) 1978-05-10 1978-05-10 Antibiotic and antifungal cerulenin derivs. - prepd. from a 5-sulphonyloxy 1,2-isopropylidene xylofuranose

Publications (2)

Publication Number Publication Date
FR2425432A1 true FR2425432A1 (en) 1979-12-07
FR2425432B1 FR2425432B1 (en) 1980-10-31

Family

ID=9208117

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7813942A Granted FR2425432A1 (en) 1978-05-10 1978-05-10 Antibiotic and antifungal cerulenin derivs. - prepd. from a 5-sulphonyloxy 1,2-isopropylidene xylofuranose

Country Status (1)

Country Link
FR (1) FR2425432A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158677B2 (en) 2007-06-01 2012-04-17 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NV134A/76 *
NV134A/77 *
NV6013/77 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158677B2 (en) 2007-06-01 2012-04-17 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
EP2572712A2 (en) 2007-06-01 2013-03-27 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
EP2581081A2 (en) 2007-06-01 2013-04-17 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US9029413B2 (en) 2007-06-01 2015-05-12 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US9757407B2 (en) 2007-06-01 2017-09-12 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways

Also Published As

Publication number Publication date
FR2425432B1 (en) 1980-10-31

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