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FR2425074A1 - REAGENT AND METHOD FOR DETECTION OF HEPATITIS B - Google Patents

REAGENT AND METHOD FOR DETECTION OF HEPATITIS B

Info

Publication number
FR2425074A1
FR2425074A1 FR7911263A FR7911263A FR2425074A1 FR 2425074 A1 FR2425074 A1 FR 2425074A1 FR 7911263 A FR7911263 A FR 7911263A FR 7911263 A FR7911263 A FR 7911263A FR 2425074 A1 FR2425074 A1 FR 2425074A1
Authority
FR
France
Prior art keywords
hba
reagent
concerns
analyzed
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7911263A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Cancer Research Royal Cancer Hospital
Institute for Cancer Research
Original Assignee
Institute of Cancer Research Royal Cancer Hospital
Institute for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Cancer Research Royal Cancer Hospital, Institute for Cancer Research filed Critical Institute of Cancer Research Royal Cancer Hospital
Publication of FR2425074A1 publication Critical patent/FR2425074A1/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G01N33/5764—Hepatitis B surface antigen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'INVENTION A TRAIT AU DOMAINE DE L'ANALYSE MEDICALE. ELLE CONCERNE UN REACTIF ANALYTIQUE DESTINE A ETRE UTILISE POUR DECELER LA PRESENCE OU L'ABSENCE DE HBA DANS UN ECHANTILLON A ANALYSER, COMPRENANT UN SUBSTRAT SUR LEQUEL SONT FIXEES UNE PREMIERE COUCHE FORMEE DE HBA ET UNE SECONDE COUCHE FORMEE D'ANTI-HB QUI RECOUVRE A PEU PRES COMPLETEMENT LA PREMIERE COUCHE DE HBA, L'ANTI-HB OCCUPANT A PEU PRES TOTALEMENT LES SITES REACTIFS DE L'ANTIGENE HBA ET LAISSANT UN EXCES NOTABLE DE SITES REACTIFS D'ANTICORPS A L'ETAT LIBRE, EN SORTE QUE L'ANTI-HB SE TIENT PRET A REAGIR AVEC TOUT HBA PRESENT DANS L'ECHANTILLON A ANALYSER AUQUEL LEDIT REACTIF EST AJOUTE. ELLE CONCERNE EGALEMENT UN PROCEDE DE PREPARATION DE CE REACTIF.THE INVENTION RELATES TO THE FIELD OF MEDICAL ANALYSIS. IT CONCERNS AN ANALYTICAL REAGENT INTENDED TO BE USED TO DETECT THE PRESENCE OR THE ABSENCE OF HBA IN A SAMPLE TO BE ANALYZED, INCLUDING A SUBSTRATE ON WHICH ARE FIXED A FIRST LAYER FORMED OF HBA AND A SECOND LAYER FORMED WITH ANALYZE HBA. ABOUT THE FIRST LAYER OF HBA COMPLETELY, ANTI-HB OCCUPYING RIGHTLY COMPLETELY THE REACTIVE SITES OF THE HBA ANTIGEN AND LEAVING A NOTABLE EXCESS OF REACTIVE ANTIBODY SITES IN THE FREE STATE, SO THAT THE ANTI-HB STANDS READY TO REACT WITH ANY HBA PRESENT IN THE SAMPLE TO BE ANALYZED TO WHICH THE REAGENT IS ADDED. IT ALSO CONCERNS A PROCESS FOR THE PREPARATION OF THIS REAGENT.

FR7911263A 1978-05-05 1979-05-04 REAGENT AND METHOD FOR DETECTION OF HEPATITIS B Pending FR2425074A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/903,238 US4189464A (en) 1978-05-05 1978-05-05 Hepatitis B testing reagent and method

Publications (1)

Publication Number Publication Date
FR2425074A1 true FR2425074A1 (en) 1979-11-30

Family

ID=25417162

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7911263A Pending FR2425074A1 (en) 1978-05-05 1979-05-04 REAGENT AND METHOD FOR DETECTION OF HEPATITIS B

Country Status (13)

Country Link
US (1) US4189464A (en)
JP (1) JPS5551358A (en)
AU (1) AU521481B2 (en)
BE (1) BE876053A (en)
BR (1) BR7902744A (en)
CA (1) CA1113388A (en)
DE (1) DE2917658A1 (en)
DK (1) DK185979A (en)
FR (1) FR2425074A1 (en)
GB (1) GB2025045B (en)
IT (1) IT1116839B (en)
LU (1) LU81222A1 (en)
NL (1) NL7903456A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459482A1 (en) * 1979-06-14 1981-01-09 Abbott Lab METHODS AND REAGENTS FOR THE SIMULTANEOUS DETECTION OF DIFFERENT MARKERS OF HEPATITIS

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293538A (en) * 1979-04-20 1981-10-06 Merck & Co. Inc. Assay for hepatitis A antigen
US4399229A (en) * 1980-04-14 1983-08-16 Immutron, Inc. Rapid radioimmunoassay product and method of making and using same
US4464474A (en) * 1980-07-09 1984-08-07 Connaught Laboratories Limited Non-A, non-B hepatitis assay and vaccine
US4474877A (en) * 1980-09-19 1984-10-02 Research And Education Institute, Inc. Harbor - Ucla Medical Center Process for detection and measurement of viral specific immunoglobulins and article of manufacture therefor
EP0071635B1 (en) * 1981-01-30 1986-04-30 Centocor, Inc. Immunoassay for multi-determinant antigens
US4617260A (en) * 1981-02-27 1986-10-14 Merck & Co., Inc. RIA assay for HBcAg
EP0063810B1 (en) * 1981-04-29 1986-03-05 Ciba-Geigy Ag New devices and kits for immunological analysis
US4433059A (en) * 1981-09-08 1984-02-21 Ortho Diagnostic Systems Inc. Double antibody conjugate
US4493899A (en) * 1981-10-16 1985-01-15 City Of Hope Method of testing for particular antibodies in the serum of a patient
US4604348A (en) * 1981-11-19 1986-08-05 New York Blood Center, Inc. Composition for use in immunoassays
FR2531718B1 (en) * 1982-08-16 1986-11-21 Sanofi Sa REAGENT ALLOWING A VERY HIGH SENSITIVITY OF THE CHARACTERISTIC ANTIGEN OF HEPATITIS B VIRUS IN HUMAN BIOLOGICAL LIQUIDS
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
GB8500918D0 (en) * 1985-01-15 1985-02-20 Cancer Res Inst Viral isolates
US4833087A (en) * 1987-02-27 1989-05-23 Eastman Kodak Company Disposable container configured to produce uniform signal
JP3387881B2 (en) 1999-03-17 2003-03-17 ティーディーケイ株式会社 Electronic component insertion head and electronic component insertion device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2257259A1 (en) * 1973-08-30 1975-08-08 Gen Electric

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3646346A (en) * 1968-12-26 1972-02-29 Pharmacia Ab Antibody-coated tube system for radioimmunoassay
US3872225A (en) * 1970-04-30 1975-03-18 Us Health Process of viral diagnosis and reagent
US3867517A (en) * 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
US4012494A (en) * 1971-12-21 1977-03-15 Abbott Laboratories Direct radioimmunoassay for antigens and their antibodies
US3904367A (en) * 1973-08-15 1975-09-09 Gen Electric Contrast enhancement for immunological film detection
US4108972A (en) * 1974-03-15 1978-08-22 Dreyer William J Immunological reagent employing radioactive and other tracers
US4041146A (en) * 1975-05-01 1977-08-09 General Electric Company Method for detection of biological particles
US4092408A (en) * 1975-08-28 1978-05-30 New England Nuclear Corporation Method for solid phase immunological assay of antigen
US4067959A (en) * 1976-05-10 1978-01-10 International Diagnostic Technology, Inc. Indirect solid surface test for antigens or antibodies

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2257259A1 (en) * 1973-08-30 1975-08-08 Gen Electric

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459482A1 (en) * 1979-06-14 1981-01-09 Abbott Lab METHODS AND REAGENTS FOR THE SIMULTANEOUS DETECTION OF DIFFERENT MARKERS OF HEPATITIS

Also Published As

Publication number Publication date
AU521481B2 (en) 1982-04-01
GB2025045A (en) 1980-01-16
GB2025045B (en) 1982-12-01
DK185979A (en) 1979-11-06
DE2917658A1 (en) 1979-11-15
US4189464A (en) 1980-02-19
IT7948937A0 (en) 1979-05-04
BE876053A (en) 1979-09-03
JPS5551358A (en) 1980-04-15
BR7902744A (en) 1979-11-27
IT1116839B (en) 1986-02-10
LU81222A1 (en) 1979-12-06
NL7903456A (en) 1979-11-07
AU4668279A (en) 1979-11-29
CA1113388A (en) 1981-12-01

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