[go: up one dir, main page]

FR2457864A2 - Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose - Google Patents

Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose

Info

Publication number
FR2457864A2
FR2457864A2 FR7914214A FR7914214A FR2457864A2 FR 2457864 A2 FR2457864 A2 FR 2457864A2 FR 7914214 A FR7914214 A FR 7914214A FR 7914214 A FR7914214 A FR 7914214A FR 2457864 A2 FR2457864 A2 FR 2457864A2
Authority
FR
France
Prior art keywords
cerulenin
chiral synthesis
desoxy
furanose
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7914214A
Other languages
French (fr)
Inventor
Pierre Sinay
Marek Pietraszkiewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Boehringer Ingelheim
Original Assignee
Laboratoires Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Boehringer Ingelheim filed Critical Laboratoires Boehringer Ingelheim
Priority to FR7914214A priority Critical patent/FR2457864A2/en
Publication of FR2457864A2 publication Critical patent/FR2457864A2/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDE DE SYNTHESE CHIRALE DES ENONTIOMERES DE FORMULE: (CF DESSIN DANS BOPI) (R RADICAL HYDROCARBONE, SATURE OU NON, EN C1-C12). CE PROCEDE COMPREND LES ETAPES:(A) (CF DESSIN DANS BOPI) R GROUPE PARTANT R GROUPE ACETALIQUE OU BENZYLE A LA SYNTHESE CHIRALE DE LA CERULENINE ET DE SES DERIVES.CHIRAL SYNTHESIS OF THE ENONTIOMERS OF FORMULA: (CF DRAWING IN BOPI) (R RADICAL HYDROCARBON, SATURATED OR NOT, IN C1-C12). THIS PROCESS INCLUDES THE STEPS: (A) (CF DRAWING IN BOPI) R START GROUP R ACETALIC OR BENZYL GROUP TO CHIRAL SYNTHESIS OF CERULENIN AND ITS DERIVATIVES.

FR7914214A 1979-06-01 1979-06-01 Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose Pending FR2457864A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7914214A FR2457864A2 (en) 1979-06-01 1979-06-01 Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7914214A FR2457864A2 (en) 1979-06-01 1979-06-01 Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose

Publications (1)

Publication Number Publication Date
FR2457864A2 true FR2457864A2 (en) 1980-12-26

Family

ID=9226181

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7914214A Pending FR2457864A2 (en) 1979-06-01 1979-06-01 Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose

Country Status (1)

Country Link
FR (1) FR2457864A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531961A1 (en) * 1982-08-18 1984-02-24 Chevron Res 5-DEOXY-3-O- (ARYLMETHYL OR SUBSTITUTED ARYLMETHYL) -1,2-O-ALKYLIDENE-A-D-XYLOFURANOSES, HERBICIDAL COMPOSITIONS CONTAINING SAME AND APPLICATIONS THEREOF
US8158677B2 (en) 2007-06-01 2012-04-17 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EXBK/75 *
EXBK/77 *
EXBK/78 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531961A1 (en) * 1982-08-18 1984-02-24 Chevron Res 5-DEOXY-3-O- (ARYLMETHYL OR SUBSTITUTED ARYLMETHYL) -1,2-O-ALKYLIDENE-A-D-XYLOFURANOSES, HERBICIDAL COMPOSITIONS CONTAINING SAME AND APPLICATIONS THEREOF
US8158677B2 (en) 2007-06-01 2012-04-17 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
EP2572712A2 (en) 2007-06-01 2013-03-27 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
EP2581081A2 (en) 2007-06-01 2013-04-17 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US9029413B2 (en) 2007-06-01 2015-05-12 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US9757407B2 (en) 2007-06-01 2017-09-12 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways

Similar Documents

Publication Publication Date Title
FR2392016A1 (en) MEVALONOLACTONE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
FR2598146B1 (en) NEW PROCESS FOR THE PREPARATION OF FIBRATES.
FR2431498A1 (en) PROCESS FOR THE PREPARATION OF MAYTANSINOIDS AND PRODUCTS OBTAINED BY THIS PROCESS
FR2357556A1 (en) PROCESS FOR TRANSFORMATION OF CIS-HEXAHYDRODIBENZO (B, D) PYRAN-9-ONES INTO TRANS-HEXAHYDRODIBENZO (B, D) PYRAN-9-ONES
FR2374307A1 (en) 1,4-DIHYDROPYRIDINE DERIVATIVES, THE PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
FR2361359A1 (en) NEW OXIMES HYDRAZONES AND THEIR PREPARATION PROCESS
FR2384811A1 (en) NEOCARZINOSTATIN DERIVATIVES, THEIR THERAPEUTIC APPLICATION AND THEIR PREPARATION PROCESS
FR2457864A2 (en) Chiral synthesis for prepn. of cerulenin enantiomers - starting from 5,6-di:desoxy 1,2-O-isopropylidene-alpha-d-xylo-hex-5-eno:furanose
IT1099762B (en) PROCEDURE FOR MICROBIOLOGICAL MODIFICATION OF HARD WOOD BY ACTION OF MICROORGANISMS
FR2314192A1 (en) PROCESS FOR PREPARATION OF OXAPHOSPHOLANES-1,2
FR2385670A1 (en) PROCESS FOR PREPARING 2,2-DIMETHYLOLALCANALS
PT67958A (en) PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES
PT67969A (en) PROCESS FOR THE PREPARATION OF AMINO ALCOHOL DERIVATIVES
ES516158A0 (en) PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF ADAMANTANE.
IT7819138A0 (en) PROCEDURE FOR THE CULTURE OF MICROORGANISMS.
FR2369288A1 (en) PROCESS FOR THE PREPARATION OF ORGANIC TIN COMPOUNDS
FR2446841A1 (en) PROCESS FOR THE PREPARATION OF 1A, 3B-DIHYDROXY-D5-STEROIDES
FR2385672A1 (en) PROCESS FOR THE PREPARATION OF HALOGENO-CYCLOBUTANONES
FR2453164A1 (en) NOVEL PHENOTHIAZINE DERIVATIVES AND THEIR PREPARATION METHOD, AND MEDICAMENTS CONTAINING SAID DERIVATIVES
FR2368489A1 (en) CLAVULIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
PT69327A (en) PROCESS FOR THE ISOMERISATION OF VINYL-3 PIPERIDINE DERIVATIVES
FR2379523A1 (en) PROCESS FOR PREPARATION OF INDOLINE DERIVATIVES
FR2278702A1 (en) PROCESS FOR FIXING ENZYMES ON SUPPORTS
FR2491493B1 (en) PROCESS FOR THE PREPARATION OF L-ISOLEUCIN BY FERMENTATION
FR2378798A1 (en) PROCESS FOR PREPARING DERIVATIVES OF 1 A-HYDROXY-CHOLESTEROL