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FR2449447A1 - Adjuvant pour favoriser l'absorption de substances therapeutiquement actives dans l'appareil digestif - Google Patents

Adjuvant pour favoriser l'absorption de substances therapeutiquement actives dans l'appareil digestif

Info

Publication number
FR2449447A1
FR2449447A1 FR8003909A FR8003909A FR2449447A1 FR 2449447 A1 FR2449447 A1 FR 2449447A1 FR 8003909 A FR8003909 A FR 8003909A FR 8003909 A FR8003909 A FR 8003909A FR 2449447 A1 FR2449447 A1 FR 2449447A1
Authority
FR
France
Prior art keywords
group
active substances
promote
absorption
therapeutically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8003909A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyoto Pharmaceutical Industries Ltd
Original Assignee
Kyoto Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries Ltd filed Critical Kyoto Pharmaceutical Industries Ltd
Publication of FR2449447A1 publication Critical patent/FR2449447A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LES B-DICETONES AYANT LA FORMULE SUIVANTE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN GROUPE ALCOYLE SUBSTITUE PAR UN OU PLUSIEURS SUBSTITUANTS CHOISIS PARMI LES GROUPES HYDROXY, SULFO, CARBOXY, PHOSPHO ET AMINO, Y COMPRIS LEURS DERIVES, ET AMMONIO, OU UN GROUPE ARALCOYLE, ARYLE OU DES GROUPES HETEROCYCLIQUES QUI PEUVENT EVENTUELLEMENT ETRE SUBSTITUES PAR UN OU PLUSIEURS MEMBRES DU GROUPE DE SUBSTITUANTS MENTIONNE CI-DESSUS, OU UN GROUPE HETEROCYCLE-ALCOYLENE ALCOYLE; Y EST UN ATOME D'OXYGENE, UN ATOME DE SOUFRE OU UN GROUPE IMINO; R EST UN GROUPE ALCOYLE, FAVORISENT L'ABSORPTION DE SUBSTANCES THERAPEUTIQUEMENT ACTIVES PAR LE COURANT SANGUIN DANS L'APPAREIL DIGESTIF ET SONT CAPABLES D'AUGMENTER EFFICACEMENT LA CONCENTRATION DE CES SUBSTANCES ACTIVES DANS LE SANG MEME QUAND CES SUBSTANCES ACTIVES NE SONT ABSORBABLES DANS L'APPAREIL DIGESTIF QU'AVEC UNE DIFFICULTE CONSIDERABLE.
FR8003909A 1979-02-26 1980-02-22 Adjuvant pour favoriser l'absorption de substances therapeutiquement actives dans l'appareil digestif Withdrawn FR2449447A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2244679A JPS55113723A (en) 1979-02-26 1979-02-26 Drug composition to be absorbed in digestive canal

Publications (1)

Publication Number Publication Date
FR2449447A1 true FR2449447A1 (fr) 1980-09-19

Family

ID=12082929

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8003909A Withdrawn FR2449447A1 (fr) 1979-02-26 1980-02-22 Adjuvant pour favoriser l'absorption de substances therapeutiquement actives dans l'appareil digestif

Country Status (3)

Country Link
JP (1) JPS55113723A (fr)
FR (1) FR2449447A1 (fr)
GB (1) GB2046091A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009145A1 (fr) * 1993-09-30 1995-04-06 Eastman Chemical Company ESTERS DE GLYCEROL DE β-ACYLOXY BUTYRATES NUTRITIFS

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0037943B1 (fr) * 1980-03-31 1985-08-14 Teijin Limited Composition pharmaceutique pour administration rectale et suppositoire ainsi préparé
US4582820A (en) * 1982-12-23 1986-04-15 Research Corporation Orally administered biologically active peptides and proteins
JPS6212746A (ja) * 1985-07-11 1987-01-21 Hoechst Gosei Kk アセトアセチル化ポリブタジエン系オリゴマーの製造方法
US5420335A (en) * 1993-09-30 1995-05-30 Birkhahn; Ronald H. Parenteral nutrients based on watersoluble glycerol bisacetoacetates
WO1995009144A1 (fr) * 1993-09-30 1995-04-06 Eastman Chemical Company Esters de glycerol d'acide hydroxybutyrique hydrosolubles utilises comme nutriments
EP0881253A1 (fr) * 1997-05-27 1998-12-02 Akcros Chemicals Esters bêta-cétoiques pour utilisation comme stabilisateurs de polymères
CN113966323B (zh) * 2019-06-12 2023-11-28 凯托利皮克斯治疗有限责任公司 一种用于生产酮羧酸多元醇基酯的方法
EP3983371A1 (fr) * 2019-07-05 2022-04-20 Arxada AG Procédé de préparation de composés d'ester d'acétoacétate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009609A2 (fr) * 1978-08-26 1980-04-16 Kyoto Yakuhin Kogyo Kabushiki Kaisha Adjuvant pour stimuler l'absorption de substances thérapeutiques actives par le tractus digestif, composition pharmaceutique contenant cet adjuvant et procédé pour la préparation de cette composition pharmaceutique; dérivés d'énamines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009609A2 (fr) * 1978-08-26 1980-04-16 Kyoto Yakuhin Kogyo Kabushiki Kaisha Adjuvant pour stimuler l'absorption de substances thérapeutiques actives par le tractus digestif, composition pharmaceutique contenant cet adjuvant et procédé pour la préparation de cette composition pharmaceutique; dérivés d'énamines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009145A1 (fr) * 1993-09-30 1995-04-06 Eastman Chemical Company ESTERS DE GLYCEROL DE β-ACYLOXY BUTYRATES NUTRITIFS

Also Published As

Publication number Publication date
GB2046091A (en) 1980-11-12
JPS55113723A (en) 1980-09-02

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Legal Events

Date Code Title Description
ST Notification of lapse