FR2334356A1 - Thieno pyridines and salts - having sedative, antiinflammatory, analgesic and platelet aggregation-inhibiting activity - Google Patents
Thieno pyridines and salts - having sedative, antiinflammatory, analgesic and platelet aggregation-inhibiting activityInfo
- Publication number
- FR2334356A1 FR2334356A1 FR7537733A FR7537733A FR2334356A1 FR 2334356 A1 FR2334356 A1 FR 2334356A1 FR 7537733 A FR7537733 A FR 7537733A FR 7537733 A FR7537733 A FR 7537733A FR 2334356 A1 FR2334356 A1 FR 2334356A1
- Authority
- FR
- France
- Prior art keywords
- thieno
- sedative
- analgesic
- platelet aggregation
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000000932 sedative agent Substances 0.000 title abstract 2
- 230000001624 sedative effect Effects 0.000 title abstract 2
- 208000010110 spontaneous platelet aggregation Diseases 0.000 title abstract 2
- 229940125670 thienopyridine Drugs 0.000 title 1
- 239000002175 thienopyridine Substances 0.000 title 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- CLCQFDFMLIWECE-UHFFFAOYSA-N 2-hydroxybenzoic acid;thieno[2,3-c]pyridine Chemical compound C1=NC=C2SC=CC2=C1.OC(=O)C1=CC=CC=C1O CLCQFDFMLIWECE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000010802 sludge Substances 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- GDQBPBMIAFIRIU-UHFFFAOYSA-N thieno[2,3-c]pyridine Chemical compound C1=NC=C2SC=CC2=C1 GDQBPBMIAFIRIU-UHFFFAOYSA-N 0.000 abstract 1
- PYEZYNAHBMWJFR-UHFFFAOYSA-N thieno[3,2-c]pyridine Chemical compound N1=CC=C2S[C]=CC2=C1 PYEZYNAHBMWJFR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Medicaments contg. thieno (2,3-c)pyridine (I) or thieno (3,2-c)pyridine (II), or an organic or mineral pharmaceutically acceptable salts are new- (I) and (II) have sedative, anti-inflammatory, analgesic, platelet aggregation inhibiting, and anti-sludge activity. A typical compound is thieno (2,3-c) pyridine salicylate (Ia). Capsules were prepd. contg. 0.10 g (Ia) 0.010 g talc, and 0.005 g magnesium stearate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7537733A FR2334356A1 (en) | 1975-12-10 | 1975-12-10 | Thieno pyridines and salts - having sedative, antiinflammatory, analgesic and platelet aggregation-inhibiting activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7537733A FR2334356A1 (en) | 1975-12-10 | 1975-12-10 | Thieno pyridines and salts - having sedative, antiinflammatory, analgesic and platelet aggregation-inhibiting activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2334356A1 true FR2334356A1 (en) | 1977-07-08 |
| FR2334356B1 FR2334356B1 (en) | 1978-07-28 |
Family
ID=9163556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7537733A Granted FR2334356A1 (en) | 1975-12-10 | 1975-12-10 | Thieno pyridines and salts - having sedative, antiinflammatory, analgesic and platelet aggregation-inhibiting activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2334356A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2440738A1 (en) * | 1978-11-13 | 1980-06-06 | Parcor | Antiinflammatory, analgesic thieno:pyridine(s) - prepd. by treating a 3-bromo-thieno-pyridine with cuprous cyanide, and opt. hydrolysing |
| WO1999062908A3 (en) * | 1998-06-04 | 2000-03-30 | Abbott Lab | Cell adhesion-inhibiting antinflammatory compounds |
| WO2000075145A1 (en) * | 1999-06-03 | 2000-12-14 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
-
1975
- 1975-12-10 FR FR7537733A patent/FR2334356A1/en active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2440738A1 (en) * | 1978-11-13 | 1980-06-06 | Parcor | Antiinflammatory, analgesic thieno:pyridine(s) - prepd. by treating a 3-bromo-thieno-pyridine with cuprous cyanide, and opt. hydrolysing |
| WO1999062908A3 (en) * | 1998-06-04 | 2000-03-30 | Abbott Lab | Cell adhesion-inhibiting antinflammatory compounds |
| US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| US6579882B2 (en) | 1998-06-04 | 2003-06-17 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| WO2000075145A1 (en) * | 1999-06-03 | 2000-12-14 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2334356B1 (en) | 1978-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |