FR2331335B2 - - Google Patents
Info
- Publication number
- FR2331335B2 FR2331335B2 FR7425285A FR7425285A FR2331335B2 FR 2331335 B2 FR2331335 B2 FR 2331335B2 FR 7425285 A FR7425285 A FR 7425285A FR 7425285 A FR7425285 A FR 7425285A FR 2331335 B2 FR2331335 B2 FR 2331335B2
- Authority
- FR
- France
- Prior art keywords
- alkyl
- optionally substituted
- formula
- naphthoyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- -1 2 - tetrahydrofuranyl Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- XSDLSEOIVCVTQZ-UHFFFAOYSA-N 2h-cyclopenta[b]furan Chemical class C1=CC2=CCOC2=C1 XSDLSEOIVCVTQZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001038 naphthoyl group Chemical group C1(=CC=CC2=CC=CC=C12)C(=O)* 0.000 abstract 2
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
1436832 Cyclopenta[b]furan derivatives UPJOHN CO 19 July 1974 [20 July 1973] 32011/74 Addition to 1396207 Heading C2C The invention comprises optically active cyclopenta[b]furan derivatives of the Formula I or racemates thereof, wherein C n H 2n is C 1-9 alkylene, with 1 to 6 carbon atoms in the chain between -CFR 2 and terminal methyl; R 2 is H, F, CH 3 or CH 2 CH 3 ; M is and R 6 is H, in which case one of R 7 and R 9 is H and the other is C 1-4 alkyl, or R 6 is Z (where Z is 2 - tetrahydrofuranyl, 2 - tetrahydropyranyl or wherein R 11 is C 1-18 alkyl, C 3-10 cycloalkyl, C 7-12 aralkyl or phenyl optionally substituted by 1, 2 or 3 C 1-4 alkyl groups, R 12 and R 13 are H, C 1-4 alkyl or phenyl optionally substituted by 1, 2 or 3 C 1-4 alkyl groups, or, when R 12 and R 13 are taken together -(CH 2 ) a or (CH 2 )b-O-(CH 2 ) c , where a is 3, 4 or 5, b is 1, 2 or 3 and c is 1, 2 or 3 with the proviso that b+c is 2, 3 or 4, and R 14 is H or phenyl) in which case R 7 is H and R 9 is C 1-4 alkyl or Z, or R 7 is C 1-4 alkyl and R 9 is Z; with the proviso that when R 6 and R 9 are both Z and R 7 is H, Z is not 2-tetrahydropyranyl; and compounds of the above Formula I in which R 6 is acetyl or optionally substituted benzoyl or naphthoyl, and R 7 is H and R 9 is C 1-4 alkyl or R 7 is C 1-4 alkyl and R 9 is H, and their preparation. The compounds are obtained by standard methods from ketones of the Formula XXIX where R 3 is acetyl or optionally substituted benzoyl or naphthoyl.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38115573A | 1973-07-20 | 1973-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2331335A2 FR2331335A2 (en) | 1977-06-10 |
| FR2331335B2 true FR2331335B2 (en) | 1979-05-25 |
Family
ID=23503911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7425285A Granted FR2331335A2 (en) | 1973-07-20 | 1974-07-19 | NEW PROSTAGLANDINS AND THEIR PREPARATION |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5037770A (en) |
| BE (1) | BE817846R (en) |
| CH (1) | CH605729A5 (en) |
| FR (1) | FR2331335A2 (en) |
| GB (2) | GB1436832A (en) |
| NL (1) | NL7409778A (en) |
| ZA (2) | ZA744580B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4642724A (en) * | 1982-06-22 | 1987-02-10 | S&C Electric Company | Trip signal generator for a circuit interrupter |
| GB8324004D0 (en) * | 1983-09-07 | 1983-10-12 | Erba Farmitalia | 16-fluoro-16 17-didehydro prostanoids |
| MXPA03010510A (en) * | 2001-05-18 | 2004-03-02 | Sucampo Ag | Cathartic composition. |
-
1974
- 1974-07-17 JP JP49081239A patent/JPS5037770A/ja active Pending
- 1974-07-17 ZA ZA00744580A patent/ZA744580B/en unknown
- 1974-07-17 ZA ZA00744581A patent/ZA744581B/en unknown
- 1974-07-19 NL NL7409778A patent/NL7409778A/en not_active Application Discontinuation
- 1974-07-19 BE BE146727A patent/BE817846R/en active
- 1974-07-19 FR FR7425285A patent/FR2331335A2/en active Granted
- 1974-07-19 GB GB3201174A patent/GB1436832A/en not_active Expired
- 1974-07-19 CH CH999374A patent/CH605729A5/xx not_active IP Right Cessation
- 1974-07-19 GB GB3200974A patent/GB1436831A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1436832A (en) | 1976-05-26 |
| FR2331335A2 (en) | 1977-06-10 |
| CH605729A5 (en) | 1978-10-13 |
| ZA744580B (en) | 1975-07-30 |
| ZA744581B (en) | 1975-07-30 |
| GB1436831A (en) | 1976-05-26 |
| JPS5037770A (en) | 1975-04-08 |
| NL7409778A (en) | 1975-01-22 |
| BE817846R (en) | 1975-01-20 |
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