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FR2305185A2 - 7-Acylamino cephalosporin derivs - antibacterials active against Gram positive and Gram negative bacteria - Google Patents

7-Acylamino cephalosporin derivs - antibacterials active against Gram positive and Gram negative bacteria

Info

Publication number
FR2305185A2
FR2305185A2 FR7509517A FR7509517A FR2305185A2 FR 2305185 A2 FR2305185 A2 FR 2305185A2 FR 7509517 A FR7509517 A FR 7509517A FR 7509517 A FR7509517 A FR 7509517A FR 2305185 A2 FR2305185 A2 FR 2305185A2
Authority
FR
France
Prior art keywords
alkyl
negative bacteria
active against
phenylalkyl
gram negative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7509517A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AR258603A priority Critical patent/AR207148A1/en
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7509517A priority patent/FR2305185A2/en
Priority to NL7504869A priority patent/NL7504869A/en
Priority to DK188375A priority patent/DK188375A/en
Priority to SE7505066A priority patent/SE7505066L/en
Priority to LU72391A priority patent/LU72391A1/xx
Priority to FI751296A priority patent/FI751296A7/fi
Priority to NO751551A priority patent/NO751551L/no
Priority to IL47212A priority patent/IL47212A0/en
Priority to SU752133307A priority patent/SU589920A3/en
Priority to HU75RO00000839A priority patent/HU171666B/en
Priority to US05/573,110 priority patent/US4034088A/en
Priority to GB1830575A priority patent/GB1459370A/en
Priority to CA226,045A priority patent/CA1032157A/en
Priority to CH559575A priority patent/CH602753A5/xx
Priority to JP50052628A priority patent/JPS50154283A/ja
Priority to ES437383A priority patent/ES437383A1/en
Priority to DE19752519503 priority patent/DE2519503A1/en
Priority to AU80790/75A priority patent/AU497840B2/en
Priority to ES441744A priority patent/ES441744A1/en
Priority to ES441746A priority patent/ES441746A1/en
Priority to AR208736A priority patent/AR208736A1/en
Priority to JP65676A priority patent/JPS51113892A/en
Publication of FR2305185A2 publication Critical patent/FR2305185A2/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

Cpds. of formula (I) and metal salts and addition salts with nitrogen bases are new (where R is 1-4C alkyl or phenylalkyl with 1-4C in the alkyl part; n is 0, 1 or 2; R1 is H, acetoxy, (5-methyl-1,3,4-thia-diazol-2-yl)thio or (1-methyl-1,2,3,4-tetrazol-5-yl)-thio; R2 is carboxy or CO2CH(R3)OCOR4 in which CH(R3)OCOR4 is a gp. easily removed enzy maticallmatically; R3 is H, 1-4C alkyl, phenyl or phenylalkyl in which the alkyl part contains 1-2; R4 is 1-4C alkyl, 1-4C alkoxy, cyclohexyl, phenyl or phenylalkyl in which the alkyl part contains 1-2C; or R1 is pyridino and R2 is carboxylato ion, provided that when R is alkyl, R1 is H or acetoxy and R2 is carboxy or R1 is pyridino and R2 is carboxylato ion, n must be 1 or 2). (I) are antibacterials active against Gram positive and Gram negative bacteria in vitro and in vivo. Dosages are 1-12g/day for adults.
FR7509517A 1974-05-02 1975-03-26 7-Acylamino cephalosporin derivs - antibacterials active against Gram positive and Gram negative bacteria Pending FR2305185A2 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
AR258603A AR207148A1 (en) 1974-05-02 1975-01-01 PROCEDURE FOR THE PREPARATION OF A NEW DERIVATIVE OF CEPHALOSPORIN
FR7509517A FR2305185A2 (en) 1975-03-26 1975-03-26 7-Acylamino cephalosporin derivs - antibacterials active against Gram positive and Gram negative bacteria
NL7504869A NL7504869A (en) 1974-05-02 1975-04-24 PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINE DIVATIVES AND THEIR SALTS, PROCEDURE FOR THE PREPARATION OF PREPARATIONS WITH PHARMACOLOGICAL ACTION AND THE PREPARATIONS FORMED.
US05/573,110 US4034088A (en) 1974-05-02 1975-04-30 Cephalosporin derivatives, and compositions containing them
SE7505066A SE7505066L (en) 1974-05-02 1975-04-30 PROCEDURE FOR THE PREPARATION OF CEFALSPORIN DERIVATIVES.
LU72391A LU72391A1 (en) 1974-05-02 1975-04-30
FI751296A FI751296A7 (en) 1974-05-02 1975-04-30
NO751551A NO751551L (en) 1974-05-02 1975-04-30
IL47212A IL47212A0 (en) 1974-05-02 1975-04-30 Cephalosporin derivatives,process for their preparation and pharmaceutical compositions containing them
SU752133307A SU589920A3 (en) 1974-05-02 1975-04-30 Method of preparing cephalosporin derivatives or salts thereof
HU75RO00000839A HU171666B (en) 1974-05-02 1975-04-30 SPOSOB POLUCHENIA NOVYKH PROIZVODNYKH 7-QUADRATER SKOBKA-2-SKOBKA-1-IMIDAZOLIL-SKOBKA ZAKRYTA-ACETILAMINO-QUADRATNAJA SKOBKA ZAKRYTA-3-METIL-CEF-3-EM-4-CARBONOVOE LIGHT
DK188375A DK188375A (en) 1974-05-02 1975-04-30 PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINE DERIVATIVES
CH559575A CH602753A5 (en) 1974-05-02 1975-05-01
CA226,045A CA1032157A (en) 1974-05-02 1975-05-01 Cephalosporin derivatives, preparation thereof and pharmaceutical compounds containing same
GB1830575A GB1459370A (en) 1974-05-02 1975-05-01 Cephalosporin derivatives their preparation and compositions containing them
JP50052628A JPS50154283A (en) 1974-05-02 1975-05-02
ES437383A ES437383A1 (en) 1974-05-02 1975-05-02 Cephalosporin derivatives, and compositions containing them
DE19752519503 DE2519503A1 (en) 1974-05-02 1975-05-02 NEW DERIVATIVES OF CEPHALOSPORIN, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM
AU80790/75A AU497840B2 (en) 1974-05-02 1975-05-02 Cephalosporins
ES441744A ES441744A1 (en) 1974-05-02 1975-10-13 Cephalosporin derivatives, and compositions containing them
ES441746A ES441746A1 (en) 1975-03-26 1975-10-13 Cephalosporine derivatives
AR208736A AR208736A1 (en) 1974-05-02 1975-12-09 PROCEDURE FOR THE PREPARATION OF A NEW DERIVATIVE OF CEAPHALOSPORIN
JP65676A JPS51113892A (en) 1975-03-26 1976-01-01 Cephalosporine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7509517A FR2305185A2 (en) 1975-03-26 1975-03-26 7-Acylamino cephalosporin derivs - antibacterials active against Gram positive and Gram negative bacteria

Publications (1)

Publication Number Publication Date
FR2305185A2 true FR2305185A2 (en) 1976-10-22

Family

ID=9153131

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7509517A Pending FR2305185A2 (en) 1974-05-02 1975-03-26 7-Acylamino cephalosporin derivs - antibacterials active against Gram positive and Gram negative bacteria

Country Status (3)

Country Link
JP (1) JPS51113892A (en)
ES (1) ES441746A1 (en)
FR (1) FR2305185A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59112990A (en) * 1982-12-21 1984-06-29 Asahi Chem Ind Co Ltd Novel cephalosporin

Also Published As

Publication number Publication date
JPS51113892A (en) 1976-10-07
ES441746A1 (en) 1977-08-01

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