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FR2397191A1 - STABLE PREPARATION OF CHLORAMPHENICOL FOR INJECTIONS - Google Patents

STABLE PREPARATION OF CHLORAMPHENICOL FOR INJECTIONS

Info

Publication number
FR2397191A1
FR2397191A1 FR7819873A FR7819873A FR2397191A1 FR 2397191 A1 FR2397191 A1 FR 2397191A1 FR 7819873 A FR7819873 A FR 7819873A FR 7819873 A FR7819873 A FR 7819873A FR 2397191 A1 FR2397191 A1 FR 2397191A1
Authority
FR
France
Prior art keywords
chloramphenicol
injections
stable preparation
pyrrolidone
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7819873A
Other languages
French (fr)
Other versions
FR2397191B1 (en
Inventor
Morris E Stolar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abic Ltd
Original Assignee
Abic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abic Ltd filed Critical Abic Ltd
Publication of FR2397191A1 publication Critical patent/FR2397191A1/en
Application granted granted Critical
Publication of FR2397191B1 publication Critical patent/FR2397191B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Préparation stable de chloramphénicol pour injections. Pour stabiliser des solutions de chloramphénicol dans la N-méthyl-pyrrolidone, on y incorpore 4 à 20 % et de préférence 5 à 10 % en poids de polyvinyl-pyrrolidone. L'addition de cette substance permet en outre de préparer des préparations avec des concentrations en chloramphenicol allant jusqu'à 60% et de réduire par conséquent les volumes à injecter. Application à la médecine vétérinaire.Stable preparation of chloramphenicol for injections. To stabilize solutions of chloramphenicol in N-methyl-pyrrolidone, 4 to 20% and preferably 5 to 10% by weight of polyvinyl-pyrrolidone are incorporated therein. The addition of this substance also makes it possible to prepare preparations with chloramphenicol concentrations of up to 60% and consequently to reduce the volumes to be injected. Application to veterinary medicine.

FR7819873A 1977-07-15 1978-07-04 STABLE PREPARATION OF CHLORAMPHENICOL FOR INJECTIONS Granted FR2397191A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL52533A IL52533A (en) 1977-07-15 1977-07-15 Injectable chloramphenicol composition

Publications (2)

Publication Number Publication Date
FR2397191A1 true FR2397191A1 (en) 1979-02-09
FR2397191B1 FR2397191B1 (en) 1981-12-31

Family

ID=11049656

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7819873A Granted FR2397191A1 (en) 1977-07-15 1978-07-04 STABLE PREPARATION OF CHLORAMPHENICOL FOR INJECTIONS

Country Status (13)

Country Link
JP (1) JPS5420125A (en)
AT (1) AT360149B (en)
AU (1) AU3752578A (en)
BE (1) BE869001A (en)
CA (1) CA1112572A (en)
DE (1) DE2829408A1 (en)
FR (1) FR2397191A1 (en)
GB (1) GB2000970B (en)
IE (1) IE47126B1 (en)
IL (1) IL52533A (en)
NL (1) NL7807641A (en)
NZ (1) NZ187683A (en)
ZA (1) ZA783671B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194192A (en) * 1979-07-02 1982-11-23 Pfizer Long-acting injectable composition containing sulfadimethoxine or sulfamethazine
NL8002636A (en) * 1980-05-08 1981-12-01 Gist Brocades Nv SOLOATE OF AMOXICILLINE, METHOD FOR PREPARING IT AND METHOD FOR PREPARING INJECTION PREPARATIONS FROM THIS SOLVATE
NL178941C (en) * 1982-06-15 1986-06-16 Aesculaap Bv PROCESS FOR PREPARING AN AQUEOUS OXYTETRACYCLINE PREPARATION.
JPS6031189A (en) * 1983-07-30 1985-02-16 カシオ計算機株式会社 musical tone generator
US4696814A (en) * 1985-08-21 1987-09-29 Warner-Lambert Company Parenteral phenytoin compositions
IT1197481B (en) * 1986-09-15 1988-11-30 Zambon Spa PHARMACEUTICAL PREPARATION FOR VETERINARY USE
US20030068339A1 (en) * 2001-10-02 2003-04-10 Phoenix Scientific, Inc. Veterinary florfenicol formulation that is syringeable under cold weather conditions
SI1830885T1 (en) 2004-12-21 2009-02-28 Intervet Int Bv Injectable veterinary composition comprising florfenicol
CN113694018A (en) * 2021-09-08 2021-11-26 海南制药厂有限公司制药二厂 Chloramphenicol injection and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313080A1 (en) * 1975-04-11 1976-12-31 Nelson Res & Dev TOPICAL COMPOSITION FOR THERAPEUTIC AND COSMETIC TREATMENT AND PROCESS FOR PREPARATION

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313080A1 (en) * 1975-04-11 1976-12-31 Nelson Res & Dev TOPICAL COMPOSITION FOR THERAPEUTIC AND COSMETIC TREATMENT AND PROCESS FOR PREPARATION

Also Published As

Publication number Publication date
ATA511878A (en) 1980-05-15
FR2397191B1 (en) 1981-12-31
CA1112572A (en) 1981-11-17
IE47126B1 (en) 1983-12-28
BE869001A (en) 1979-01-15
IE781425L (en) 1979-01-15
IL52533A0 (en) 1977-10-31
AU3752578A (en) 1980-01-03
DE2829408A1 (en) 1979-02-01
AT360149B (en) 1980-12-29
NL7807641A (en) 1979-01-17
ZA783671B (en) 1979-06-27
NZ187683A (en) 1981-03-16
GB2000970B (en) 1982-03-17
GB2000970A (en) 1979-01-24
IL52533A (en) 1980-01-31
JPS5420125A (en) 1979-02-15

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Legal Events

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