FR2396020A1 - NEW WATER-SOLUBLE GLYCOPEPTIDES ACETYL EXTRACTS FROM MICROBIAL BODIES LYES OF HAFNIA, AEROBACTER CLOACAE AND KLEBSIELLA PNEUMONIAE, METHOD OF PREPARATION AND APPLICATION OF THESE PRODUCTS AS MEDICINAL PRODUCTS - Google Patents
NEW WATER-SOLUBLE GLYCOPEPTIDES ACETYL EXTRACTS FROM MICROBIAL BODIES LYES OF HAFNIA, AEROBACTER CLOACAE AND KLEBSIELLA PNEUMONIAE, METHOD OF PREPARATION AND APPLICATION OF THESE PRODUCTS AS MEDICINAL PRODUCTSInfo
- Publication number
- FR2396020A1 FR2396020A1 FR7720320A FR7720320A FR2396020A1 FR 2396020 A1 FR2396020 A1 FR 2396020A1 FR 7720320 A FR7720320 A FR 7720320A FR 7720320 A FR7720320 A FR 7720320A FR 2396020 A1 FR2396020 A1 FR 2396020A1
- Authority
- FR
- France
- Prior art keywords
- products
- hafnia
- preparation
- application
- lyes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000002068 Glycopeptides Human genes 0.000 title abstract 3
- 108010015899 Glycopeptides Proteins 0.000 title abstract 3
- 241000588697 Enterobacter cloacae Species 0.000 title abstract 2
- 241000588731 Hafnia Species 0.000 title abstract 2
- CJNBYAVZURUTKZ-UHFFFAOYSA-N hafnium(IV) oxide Inorganic materials O=[Hf]=O CJNBYAVZURUTKZ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 241000588747 Klebsiella pneumoniae Species 0.000 title 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 title 1
- 239000000284 extract Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- GMKMEZVLHJARHF-UHFFFAOYSA-N (2R,6R)-form-2.6-Diaminoheptanedioic acid Natural products OC(=O)C(N)CCCC(N)C(O)=O GMKMEZVLHJARHF-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/275—Hafnia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/26—Klebsiella (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/265—Enterobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
Nouveaux glycopeptides acétyles hydrosolubles extraits de corps microbiens lysés de microorganismes choisis dans le groupe Hafnia, Aérobacter Cloacae et Klebsielia Pneumoniae ayant un poids moléculaire apparent compris entre 500 et 200 000, renfermant au moins 5 % de substances à pouvoir biurétogène, au moins 25 % d'oses neutres, ne renfermant pas d'acide diaminopimélique et présentant un maximum d'absorption en UV à environ 210 m mu . Procédé de préparation et application à titre de médicaments de ces nouveaux glycopeptides acétylés.New water-soluble acetylated glycopeptides extracted from lysed microbial bodies of microorganisms selected from the group Hafnia, Aerobacter Cloacae and Klebsielia Pneumoniae having an apparent molecular weight between 500 and 200,000, containing at least 5% of substances with biuretogenic power, at least 25% of Neutral soses, not containing diaminopimelic acid and exhibiting a maximum UV absorption at approximately 210 m mu. Process for the preparation and application as medicaments of these new acetylated glycopeptides.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7720320A FR2396020A1 (en) | 1977-07-01 | 1977-07-01 | NEW WATER-SOLUBLE GLYCOPEPTIDES ACETYL EXTRACTS FROM MICROBIAL BODIES LYES OF HAFNIA, AEROBACTER CLOACAE AND KLEBSIELLA PNEUMONIAE, METHOD OF PREPARATION AND APPLICATION OF THESE PRODUCTS AS MEDICINAL PRODUCTS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7720320A FR2396020A1 (en) | 1977-07-01 | 1977-07-01 | NEW WATER-SOLUBLE GLYCOPEPTIDES ACETYL EXTRACTS FROM MICROBIAL BODIES LYES OF HAFNIA, AEROBACTER CLOACAE AND KLEBSIELLA PNEUMONIAE, METHOD OF PREPARATION AND APPLICATION OF THESE PRODUCTS AS MEDICINAL PRODUCTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2396020A1 true FR2396020A1 (en) | 1979-01-26 |
| FR2396020B1 FR2396020B1 (en) | 1980-03-14 |
Family
ID=9192867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7720320A Granted FR2396020A1 (en) | 1977-07-01 | 1977-07-01 | NEW WATER-SOLUBLE GLYCOPEPTIDES ACETYL EXTRACTS FROM MICROBIAL BODIES LYES OF HAFNIA, AEROBACTER CLOACAE AND KLEBSIELLA PNEUMONIAE, METHOD OF PREPARATION AND APPLICATION OF THESE PRODUCTS AS MEDICINAL PRODUCTS |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2396020A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2462477A1 (en) * | 1979-07-31 | 1981-02-13 | Cassenne Lab Sa | NOVEL KLEBSIELLA PNEUMONIAE GLYCOPROTEINS, PROCESS FOR OBTAINING THEM, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM |
| EP0049182A1 (en) * | 1980-09-19 | 1982-04-07 | Roussel-Uclaf | Immunostimulating glycoproteins extracted from Klebsiella Pneumoniae, process for obtaining them, their application as medicaments and compositions containing them |
| EP0049181A1 (en) * | 1980-09-19 | 1982-04-07 | Roussel-Uclaf | Hydrosoluble immunostimulating glycoproteins extracted from Klebsiella Pneumoniae, process for obtaining them, their application as medicaments and compositions containing them |
| FR2540136A1 (en) * | 1983-01-28 | 1984-08-03 | Roussel Uclaf | NOVEL PROCESS FOR THE PREPARATION OF IMMUNOSTIMULATING ACYLGLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR CONTROLLING ALLERGIC DISEASES |
| FR2650506A1 (en) * | 1989-07-11 | 1991-02-08 | Roussel Uclaf | GALACTANNE EXTRACT OF KLEBSIELLA, PROCESS FOR OBTAINING AND APPLICATION AS A MEDICAMENT |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH314792A (en) * | 1952-05-21 | 1956-06-30 | Wander Ag Dr A | Process for the preparation of therapeutic irritants |
-
1977
- 1977-07-01 FR FR7720320A patent/FR2396020A1/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH314792A (en) * | 1952-05-21 | 1956-06-30 | Wander Ag Dr A | Process for the preparation of therapeutic irritants |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2462477A1 (en) * | 1979-07-31 | 1981-02-13 | Cassenne Lab Sa | NOVEL KLEBSIELLA PNEUMONIAE GLYCOPROTEINS, PROCESS FOR OBTAINING THEM, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM |
| EP0049182A1 (en) * | 1980-09-19 | 1982-04-07 | Roussel-Uclaf | Immunostimulating glycoproteins extracted from Klebsiella Pneumoniae, process for obtaining them, their application as medicaments and compositions containing them |
| EP0049181A1 (en) * | 1980-09-19 | 1982-04-07 | Roussel-Uclaf | Hydrosoluble immunostimulating glycoproteins extracted from Klebsiella Pneumoniae, process for obtaining them, their application as medicaments and compositions containing them |
| FR2540136A1 (en) * | 1983-01-28 | 1984-08-03 | Roussel Uclaf | NOVEL PROCESS FOR THE PREPARATION OF IMMUNOSTIMULATING ACYLGLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR CONTROLLING ALLERGIC DISEASES |
| EP0115988A1 (en) * | 1983-01-28 | 1984-08-15 | Roussel-Uclaf | Process for preparing immunostimulating acylglycoproteins extracted from Klebsiella pneumoniae, antiallergic pharmaceutical compositions |
| FR2650506A1 (en) * | 1989-07-11 | 1991-02-08 | Roussel Uclaf | GALACTANNE EXTRACT OF KLEBSIELLA, PROCESS FOR OBTAINING AND APPLICATION AS A MEDICAMENT |
| EP0408444A3 (en) * | 1989-07-11 | 1991-07-03 | Roussel-Uclaf | Galactan extracted klebsiella, process for its preparation and its use as a medicament |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2396020B1 (en) | 1980-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |