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FR2392005A1 - Analogues de la prostaglandine e1 et les compositions pharmaceutiques qui les contiennent - Google Patents

Analogues de la prostaglandine e1 et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2392005A1
FR2392005A1 FR7815523A FR7815523A FR2392005A1 FR 2392005 A1 FR2392005 A1 FR 2392005A1 FR 7815523 A FR7815523 A FR 7815523A FR 7815523 A FR7815523 A FR 7815523A FR 2392005 A1 FR2392005 A1 FR 2392005A1
Authority
FR
France
Prior art keywords
prostaglandin
analogues
pharmaceutical compositions
compositions containing
analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7815523A
Other languages
English (en)
Other versions
FR2392005B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of FR2392005A1 publication Critical patent/FR2392005A1/fr
Application granted granted Critical
Publication of FR2392005B1 publication Critical patent/FR2392005B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention a trait à des analogues de la prostaglandine E1 . Ces composés répondent à la formule ci-dessous, dans laquelle les deux chaînes latérales sont attachées aux atomes de carbone de l'anneau pentagonal selon la configuration trans. Applications pharmacologiques en particulier contre les ulcères gastriques et l'excès de sécrétion d'acide gastrique.
FR7815523A 1977-05-26 1978-05-25 Analogues de la prostaglandine e1 et les compositions pharmaceutiques qui les contiennent Granted FR2392005A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB22319/77A GB1581886A (en) 1977-05-26 1977-05-26 Prostanol derivatives

Publications (2)

Publication Number Publication Date
FR2392005A1 true FR2392005A1 (fr) 1978-12-22
FR2392005B1 FR2392005B1 (fr) 1980-04-04

Family

ID=10177472

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7815523A Granted FR2392005A1 (fr) 1977-05-26 1978-05-25 Analogues de la prostaglandine e1 et les compositions pharmaceutiques qui les contiennent

Country Status (9)

Country Link
US (1) US4158062A (fr)
JP (1) JPS53147045A (fr)
DE (1) DE2822751A1 (fr)
FR (1) FR2392005A1 (fr)
GB (1) GB1581886A (fr)
HK (1) HK28784A (fr)
IT (1) IT1094851B (fr)
MY (1) MY8400370A (fr)
SG (1) SG59183G (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009005171A1 (fr) * 2007-07-03 2009-01-08 Sucampo Ag Combinaison pharmaceutique d'un opioïde et d'un composés de prostaglandine

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8512344D0 (en) * 1985-05-15 1985-06-19 May & Baker Ltd Compositions of matter
JPH085794B2 (ja) * 1989-07-27 1996-01-24 株式会社上野製薬応用研究所 高脂質血症処置・血中脂質成分低下剤
JPH0769897A (ja) * 1993-09-01 1995-03-14 Green Cross Corp:The 血中トリグリセリド低下作用剤
TWI302100B (en) * 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
AR037524A1 (es) 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
ES2591252T3 (es) * 2002-12-27 2016-11-25 Sucampo Ag Derivados de prostaglandinas para tratar el síndrome de colon irritable y/o la dispepsia funcional
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2258845A1 (fr) * 1974-01-26 1975-08-22 May & Baker Ltd

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2258845A1 (fr) * 1974-01-26 1975-08-22 May & Baker Ltd

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009005171A1 (fr) * 2007-07-03 2009-01-08 Sucampo Ag Combinaison pharmaceutique d'un opioïde et d'un composés de prostaglandine
AU2008271981B2 (en) * 2007-07-03 2013-08-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
US10561649B2 (en) 2007-07-03 2020-02-18 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound

Also Published As

Publication number Publication date
DE2822751A1 (de) 1978-12-07
DE2822751C2 (fr) 1988-01-28
HK28784A (en) 1984-04-06
MY8400370A (en) 1984-12-31
IT1094851B (it) 1985-08-10
FR2392005B1 (fr) 1980-04-04
IT7823915A0 (it) 1978-05-26
JPS6151584B2 (fr) 1986-11-10
GB1581886A (en) 1980-12-31
US4158062A (en) 1979-06-12
SG59183G (en) 1984-07-27
JPS53147045A (en) 1978-12-21

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Legal Events

Date Code Title Description
ST Notification of lapse