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FR2387033A1 - Composition therapeutique contenant une ou plusieurs substances actives chimiquement modifiees - Google Patents

Composition therapeutique contenant une ou plusieurs substances actives chimiquement modifiees

Info

Publication number
FR2387033A1
FR2387033A1 FR7810798A FR7810798A FR2387033A1 FR 2387033 A1 FR2387033 A1 FR 2387033A1 FR 7810798 A FR7810798 A FR 7810798A FR 7810798 A FR7810798 A FR 7810798A FR 2387033 A1 FR2387033 A1 FR 2387033A1
Authority
FR
France
Prior art keywords
therapeutic composition
composition containing
active substances
chemically modified
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7810798A
Other languages
English (en)
Other versions
FR2387033B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2387033A1 publication Critical patent/FR2387033A1/fr
Application granted granted Critical
Publication of FR2387033B1 publication Critical patent/FR2387033B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne une composition thérapeutique destinée à être utilisée en médecine humaine et en médecine vétérinaire. Elle contient un pro-médicament, c'est-à-dire un composé formé d'une substance thérapeutique en combinaison chimique avec une autre portion moléculaire par une liaison pouvant être clivée par irradiation à la lumière ultraviolette, le clivage libérant la substance thérapeutique en une quantité efficace. Les pro-médicaments donnent par clivage des substances douées d'activité thérapeutique qui sont des composés s'opposant aux processus de prolifération et aux processus inflammatoires, permettant notamment le traitement de maladies inflammatoires et/ou prolifératives de la peau.
FR7810798A 1977-04-13 1978-04-12 Composition therapeutique contenant une ou plusieurs substances actives chimiquement modifiees Granted FR2387033A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/787,230 US4235887A (en) 1977-04-13 1977-04-13 Process for therapeutic treatment

Publications (2)

Publication Number Publication Date
FR2387033A1 true FR2387033A1 (fr) 1978-11-10
FR2387033B1 FR2387033B1 (fr) 1981-01-09

Family

ID=25140813

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7810798A Granted FR2387033A1 (fr) 1977-04-13 1978-04-12 Composition therapeutique contenant une ou plusieurs substances actives chimiquement modifiees

Country Status (8)

Country Link
US (1) US4235887A (fr)
JP (1) JPS53133637A (fr)
AU (1) AU516563B2 (fr)
BE (1) BE865957A (fr)
DE (1) DE2812164A1 (fr)
FR (1) FR2387033A1 (fr)
GB (2) GB1603904A (fr)
ZA (1) ZA781511B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123485A1 (fr) * 1983-04-14 1984-10-31 The Regents Of The University Of California Pro-médicament spécifique du colon, préparation et utilisation

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590211A (en) * 1977-04-13 1986-05-20 The Upjohn Company Process for therapeutic treatment
DK172081A (da) * 1980-04-21 1981-10-22 Merck & Co Inc Mercaptoforbindelse og fremgangsmaade til fremstilling deraf
US4612007A (en) * 1981-06-16 1986-09-16 Edelson Richard Leslie Method and system for externally treating the blood
US4369181A (en) * 1981-08-05 1983-01-18 Sri International Process for treating proliferative skin diseases using certain 6,8-substituted ribofuranosylpurine-3',5'-cyclic phosphates
WO1983000811A1 (fr) * 1981-09-08 1983-03-17 Stancon, Alexei Agencement et procede de photo-irradiation
US4684521A (en) * 1982-12-08 1987-08-04 Frederic A. Bourke, Jr. Method and system for externally treating the blood
US4613322A (en) * 1982-12-08 1986-09-23 Edelson Richard Leslie Method and system for externally treating the blood
US4683889A (en) * 1983-03-29 1987-08-04 Frederic A. Bourke, Jr. Method and system for externally treating the blood
US4753958A (en) * 1985-02-07 1988-06-28 University Of Cal Photochemotherapy of epithelial diseases with derivatives of hematoporphyrins
DK406686D0 (da) * 1986-08-26 1986-08-26 Hans Bundgaard Carboxylsyrederivater
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US7157458B2 (en) * 2001-04-17 2007-01-02 Cryolife, Inc. Bifunctional energy-reversible acyl-compositions
US20050009798A1 (en) * 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
WO2003070745A2 (fr) * 2002-02-20 2003-08-28 Sepracor Inc. Formes modifiees de carbonate et de carbamate de glucocorticoides
EP1511757B1 (fr) * 2002-06-07 2015-11-04 Universitair Medisch Centrum Utrecht Nouveaux composes de modulation de l'activite de proteines d'echange directement activees par camp (epac)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069322A (en) * 1976-10-12 1978-01-17 Interx Research Corporation Pro-drugs for the improved delivery of certain selected anti-inflammatory steroids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123485A1 (fr) * 1983-04-14 1984-10-31 The Regents Of The University Of California Pro-médicament spécifique du colon, préparation et utilisation

Also Published As

Publication number Publication date
GB1603903A (en) 1981-12-02
GB1603904A (en) 1981-12-02
AU516563B2 (en) 1981-06-11
JPS53133637A (en) 1978-11-21
DE2812164A1 (de) 1978-10-26
FR2387033B1 (fr) 1981-01-09
US4235887A (en) 1980-11-25
BE865957A (fr) 1978-10-13
AU3423478A (en) 1979-09-20
ZA781511B (en) 1979-03-28

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Legal Events

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