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FR2383907A1 - Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede - Google Patents

Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede

Info

Publication number
FR2383907A1
FR2383907A1 FR7707588A FR7707588A FR2383907A1 FR 2383907 A1 FR2383907 A1 FR 2383907A1 FR 7707588 A FR7707588 A FR 7707588A FR 7707588 A FR7707588 A FR 7707588A FR 2383907 A1 FR2383907 A1 FR 2383907A1
Authority
FR
France
Prior art keywords
derivatives
acetic acid
preparing
derivatives obtained
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7707588A
Other languages
English (en)
Other versions
FR2383907B1 (fr
Inventor
Michel Chignac
Claude Grain
Charles Pigerol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Priority to FR7707588A priority Critical patent/FR2383907A1/fr
Priority to IN621/CAL/77A priority patent/IN156430B/en
Priority to NO771578A priority patent/NO147521C/no
Priority to DK196077A priority patent/DK154417C/da
Priority to SE7705258A priority patent/SE418175B/xx
Priority to IL52023A priority patent/IL52023A/xx
Priority to GR53388A priority patent/GR60800B/el
Priority to LU77303A priority patent/LU77303A1/xx
Priority to CA278,112A priority patent/CA1077057A/fr
Priority to HU77LA916A priority patent/HU178811B/hu
Priority to DE2721264A priority patent/DE2721264C2/de
Priority to BE177459A priority patent/BE854488A/fr
Priority to CH596477A priority patent/CH621108A5/fr
Priority to PT66543A priority patent/PT66543B/pt
Priority to NLAANVRAGE7705564,A priority patent/NL176852C/xx
Priority to CS773336A priority patent/CS197291B2/cs
Priority to AR267719A priority patent/AR213000A1/es
Priority to US05/800,344 priority patent/US4127604A/en
Priority to DD7700199160A priority patent/DD129776A5/xx
Priority to PL1977198561A priority patent/PL108173B1/pl
Priority to JP6562877A priority patent/JPS53112806A/ja
Priority to MX775779U priority patent/MX4567E/es
Priority to GB23784/77A priority patent/GB1529786A/en
Priority to SU772489907A priority patent/SU703013A3/ru
Priority to NZ184328A priority patent/NZ184328A/xx
Priority to YU1492/77A priority patent/YU40480B/xx
Priority to FI771899A priority patent/FI63927C/fi
Priority to IE1272/77A priority patent/IE45346B1/en
Priority to AU26265/77A priority patent/AU508174B2/en
Priority to ZA00773776A priority patent/ZA773776B/xx
Priority to OA56207A priority patent/OA05695A/fr
Priority to IT25584/77A priority patent/IT1080752B/it
Priority to AT521077A priority patent/AT351011B/de
Priority to ES467890A priority patent/ES467890A1/es
Publication of FR2383907A1 publication Critical patent/FR2383907A1/fr
Application granted granted Critical
Publication of FR2383907B1 publication Critical patent/FR2383907B1/fr
Priority to DE19813103776 priority patent/DE3103776A1/de
Priority to YU36081A priority patent/YU42379B/xx
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne un procédé de préparation et dérivés de l'acide acétique ainsi que les dérivés obtenus par ce procédé. Le procédé de l'invention pour la préparation de l'acide di-n-propylacétique de formule :
FR7707588A 1977-03-15 1977-03-15 Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede Granted FR2383907A1 (fr)

Priority Applications (36)

Application Number Priority Date Filing Date Title
FR7707588A FR2383907A1 (fr) 1977-03-15 1977-03-15 Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede
IN621/CAL/77A IN156430B (fr) 1977-03-15 1977-04-25
NO771578A NO147521C (no) 1977-03-15 1977-05-04 Fremgangsmaate for fremstilling av di-n-propyleddiksyre
DK196077A DK154417C (da) 1977-03-15 1977-05-04 Fremgangsmaade til fremstilling af di-n-propyleddikesyre eller dens ikke-toksiske akalimetal- eller jordalkalimetalsalte
IL52023A IL52023A (en) 1977-03-15 1977-05-05 Process for the preparation of di-n-propyl-acetic acid and salts thereof
SE7705258A SE418175B (sv) 1977-03-15 1977-05-05 Sett for framstellning av di-n-propyl-ettikssyraderivat
GR53388A GR60800B (en) 1977-03-15 1977-05-06 Preparation process of acetic acid derivatives
LU77303A LU77303A1 (fr) 1977-03-15 1977-05-09
CA278,112A CA1077057A (fr) 1977-03-15 1977-05-10 Preparation de derives de l'acide acetique
HU77LA916A HU178811B (en) 1977-03-15 1977-05-10 Process for producing di-n-propyl-acetic acid
DE2721264A DE2721264C2 (de) 1977-03-15 1977-05-11 Verfahren zur Herstellung von Di-n-propylessigsäure und deren nichttoxischen Alkali- und Erdalkalimetallsalzen
BE177459A BE854488A (fr) 1977-03-15 1977-05-11 Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede
CH596477A CH621108A5 (fr) 1977-03-15 1977-05-12
PT66543A PT66543B (en) 1977-03-15 1977-05-13 Process for the preparation of acetic acid derivates
NLAANVRAGE7705564,A NL176852C (nl) 1977-03-15 1977-05-20 Werkwijze voor het bereiden van een dipropylazijnzuur.
CS773336A CS197291B2 (en) 1977-03-15 1977-05-20 Process for preparing di-n-propylacetic acid
AR267719A AR213000A1 (es) 1977-03-15 1977-05-20 Procedimiento para preparacion de acido di-n-propil-acetico
US05/800,344 US4127604A (en) 1977-03-15 1977-05-25 Process for the preparation of acetic acid derivatives
DD7700199160A DD129776A5 (de) 1977-03-15 1977-05-26 Verfahren zur herstellung von essigsaeurederivaten
PL1977198561A PL108173B1 (pl) 1977-03-15 1977-05-31 Sposob wytwarzania kwasu dwu-n-propylooctowego method of producing di-n-propyloacetic acid
JP6562877A JPS53112806A (en) 1977-03-15 1977-06-02 Process for preparing 33nnpropylacetate nonntoxic alkali metal salts and alkaliearth metal salts
MX775779U MX4567E (es) 1977-03-15 1977-06-03 Procedimiento para preparar acido de-n-propilacetico
GB23784/77A GB1529786A (en) 1977-03-15 1977-06-03 Process for preparing acetic acid derivatives
SU772489907A SU703013A3 (ru) 1977-03-15 1977-06-06 Способ получени ди-н-пропилуксусной кислоты или ее солей щелочных или щелочноземельных металлов
NZ184328A NZ184328A (en) 1977-03-15 1977-06-08 Preparation of di-n-propylacetic acid
YU1492/77A YU40480B (en) 1977-03-15 1977-06-15 Process for obtaining di-n-propyl acetic acid
FI771899A FI63927C (fi) 1977-03-15 1977-06-16 Foerfarande foer framstaellning av di-n-propyl-aettikssyra ochdess salter
AU26265/77A AU508174B2 (en) 1977-03-15 1977-06-21 Preparing acetic acid derivatives
IE1272/77A IE45346B1 (en) 1977-03-15 1977-06-21 Procress for preparing acetic acid derivatives
ZA00773776A ZA773776B (en) 1977-03-15 1977-06-23 Process for preparing acetic acid derivatives
OA56207A OA05695A (fr) 1977-03-15 1977-06-27 Procédé de préparation de dérivés de l'acide acétique et dérivés obtenus par ce procédé.
IT25584/77A IT1080752B (it) 1977-03-15 1977-07-11 Procedimento per la preparazione dei derivati dell'acido acetico
AT521077A AT351011B (de) 1977-03-15 1977-07-19 Verfahren zur herstellung von di-n-propyl- essigsaeure und von deren salzen
ES467890A ES467890A1 (es) 1977-03-15 1978-03-15 Procedimiento para preparar acido di-n-propilacetico.
DE19813103776 DE3103776A1 (de) 1977-03-15 1981-02-04 Verfahren zur herstellung von di-n-propyl-essigsaeure
YU36081A YU42379B (en) 1977-03-15 1981-02-12 Process for obtaining di-n-propylacetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7707588A FR2383907A1 (fr) 1977-03-15 1977-03-15 Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede

Publications (2)

Publication Number Publication Date
FR2383907A1 true FR2383907A1 (fr) 1978-10-13
FR2383907B1 FR2383907B1 (fr) 1979-07-20

Family

ID=9188073

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7707588A Granted FR2383907A1 (fr) 1977-03-15 1977-03-15 Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede

Country Status (34)

Country Link
US (1) US4127604A (fr)
JP (1) JPS53112806A (fr)
AR (1) AR213000A1 (fr)
AT (1) AT351011B (fr)
AU (1) AU508174B2 (fr)
BE (1) BE854488A (fr)
CA (1) CA1077057A (fr)
CH (1) CH621108A5 (fr)
CS (1) CS197291B2 (fr)
DD (1) DD129776A5 (fr)
DE (1) DE2721264C2 (fr)
DK (1) DK154417C (fr)
ES (1) ES467890A1 (fr)
FI (1) FI63927C (fr)
FR (1) FR2383907A1 (fr)
GB (1) GB1529786A (fr)
GR (1) GR60800B (fr)
HU (1) HU178811B (fr)
IE (1) IE45346B1 (fr)
IL (1) IL52023A (fr)
IN (1) IN156430B (fr)
IT (1) IT1080752B (fr)
LU (1) LU77303A1 (fr)
MX (1) MX4567E (fr)
NL (1) NL176852C (fr)
NO (1) NO147521C (fr)
NZ (1) NZ184328A (fr)
OA (1) OA05695A (fr)
PL (1) PL108173B1 (fr)
PT (1) PT66543B (fr)
SE (1) SE418175B (fr)
SU (1) SU703013A3 (fr)
YU (1) YU40480B (fr)
ZA (1) ZA773776B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3103776A1 (de) * 1977-03-15 1982-01-07 Sanofi, 75008 Paris Verfahren zur herstellung von di-n-propyl-essigsaeure
DE2844638C2 (de) * 1978-10-13 1987-02-26 Ruhrchemie Ag, 4200 Oberhausen Verfahren zur Herstellung von Di-n- propylessigsäure
DE2844636C2 (de) * 1978-10-13 1986-07-31 Ruhrchemie Ag, 4200 Oberhausen Verfahren zur Herstellung von Di-n- propylessigsäure
CA1136151A (fr) * 1979-08-20 1982-11-23 Abbott Laboratories Sel mixte d'acide valproique
US5212326A (en) * 1979-08-20 1993-05-18 Abbott Laboratories Sodium hydrogen divalproate oligomer
US4988731A (en) * 1979-08-20 1991-01-29 Abbott Laboratories Sodium hydrogen divalproate oligomer
FR2470758A1 (fr) * 1979-12-07 1981-06-12 Sanofi Sa Procede pour la fixation de groupes alkyles sur une chaine carbonee portant un groupe fonctionnel
JPS643178B2 (fr) * 1980-07-28 1989-01-19 Abbott Lab
IL72381A (en) * 1983-07-20 1988-03-31 Sanofi Sa Pharmaceutical composition based on valproic acid
US5101070A (en) * 1985-10-30 1992-03-31 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Process for preparing valproic acid
JPS62126651U (fr) * 1986-01-31 1987-08-11
DE3718803A1 (de) * 1987-06-02 1988-12-15 Desitin Arzneimittel Gmbh Verfahren zur herstellung von e-2-propyl-2-pentensaeure und physiologisch vertraeglichen salzen derselben
EP0632008B1 (fr) * 1993-06-01 1998-02-04 Ono Pharmaceutical Co., Ltd. Dérivés de l'acide pentanoique
US5344975A (en) * 1993-09-03 1994-09-06 Wyckoff Chemical Company, Inc. Process for production of lower alkanoic acids
JP3587473B2 (ja) * 1994-06-23 2004-11-10 日本合成化学工業株式会社 バルプロ酸の精製方法
DE102008036495A1 (de) 2008-08-04 2010-02-11 Langhals, Heinz, Prof. Dr. Persistente Pery-Imid-Radikalanionen als NIR-Farbstoffe
US8729300B2 (en) * 2009-08-11 2014-05-20 Sci Pharmtech, Inc. Method for preparing metal salt of valproic acid
CN105017007B (zh) * 2014-04-16 2019-04-16 四川科瑞德制药股份有限公司 一种丙戊酸钠化合物
CN113200848A (zh) * 2021-03-29 2021-08-03 上海青平药业有限公司 一种丙戊酸制备新方法
CN114763319B (zh) * 2022-05-16 2023-03-31 湖南大学 一种联产丙戊酰胺和丙戊酸钠的方法
CN116143586A (zh) * 2022-12-16 2023-05-23 上海青平药业有限公司 一种2-乙基-2-甲基戊酸的制备方法
CN116143658A (zh) * 2022-12-16 2023-05-23 上海青平药业有限公司 一种同时制备三丙基乙腈、三丙基酰胺、三丙基乙酸的方法
WO2025074220A1 (fr) 2023-10-06 2025-04-10 Unichem Laboratories Ltd. Procédé amélioré de fabrication d'acide valproïque et/ou de son sel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2442E (fr) * 1903-03-07 1904-04-07 Gustave Henri Boisrenoult Distributeur automatique perfectionné pour engrais ou matières pulvérulentes quelconques

Also Published As

Publication number Publication date
DK196077A (da) 1978-09-16
AU2626577A (en) 1979-01-04
MX4567E (es) 1982-06-17
DE2721264C2 (de) 1984-07-19
YU149277A (en) 1982-06-30
CH621108A5 (fr) 1981-01-15
CS197291B2 (en) 1980-04-30
LU77303A1 (fr) 1977-08-24
NL176852C (nl) 1985-06-17
US4127604A (en) 1978-11-28
DE2721264A1 (de) 1978-09-21
IE45346B1 (en) 1982-08-11
BE854488A (fr) 1977-11-14
JPS5640137B2 (fr) 1981-09-18
IT1080752B (it) 1985-05-16
PT66543A (en) 1977-06-01
DD129776A5 (de) 1978-02-08
OA05695A (fr) 1981-05-31
AU508174B2 (en) 1980-03-13
ATA521077A (de) 1978-12-15
SU703013A3 (ru) 1979-12-05
YU40480B (en) 1986-02-28
CA1077057A (fr) 1980-05-06
NO147521C (no) 1983-04-27
FI63927B (fi) 1983-05-31
SE7705258L (sv) 1978-09-16
JPS53112806A (en) 1978-10-02
NO771578L (no) 1978-09-18
FR2383907B1 (fr) 1979-07-20
PT66543B (en) 1978-10-18
FI63927C (fi) 1983-09-12
GR60800B (en) 1978-08-30
HU178811B (en) 1982-06-28
FI771899A7 (fi) 1978-09-16
NZ184328A (en) 1979-10-25
DK154417B (da) 1988-11-14
NL7705564A (nl) 1978-09-19
IL52023A0 (en) 1977-07-31
PL108173B1 (pl) 1980-03-31
IE45346L (en) 1978-09-15
IL52023A (en) 1979-10-31
IN156430B (fr) 1985-08-03
NL176852B (nl) 1985-01-16
ZA773776B (en) 1978-05-30
GB1529786A (en) 1978-10-25
NO147521B (no) 1983-01-17
AT351011B (de) 1979-07-10
SE418175B (sv) 1981-05-11
DK154417C (da) 1989-04-10
ES467890A1 (es) 1978-11-01
AR213000A1 (es) 1978-11-30
PL198561A1 (pl) 1978-10-09

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