FR2381750A1 - PHENYLACETONITRIL SUBSTITUTES AND THEIR PREPARATION - Google Patents
PHENYLACETONITRIL SUBSTITUTES AND THEIR PREPARATIONInfo
- Publication number
- FR2381750A1 FR2381750A1 FR7804716A FR7804716A FR2381750A1 FR 2381750 A1 FR2381750 A1 FR 2381750A1 FR 7804716 A FR7804716 A FR 7804716A FR 7804716 A FR7804716 A FR 7804716A FR 2381750 A1 FR2381750 A1 FR 2381750A1
- Authority
- FR
- France
- Prior art keywords
- atoms
- compounds
- phenylacetonitril
- substitutes
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 150000007962 benzene acetonitriles Chemical class 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Novel substituted phenylacetonitriles of the formula in which R denotes alkyl having 1 to 4 C atoms, and R' denotes alkyl having 1 to 4 C atoms, cycloalkyl having 5 to 7 C ring atoms, which is optionally substituted by alkyl having 1 to 4 C atoms, the benzyl group, or a benzyl group which is substituted by bromine or chlorine or the group -COOR1, in which R1 has the said meaning of R, are prepared. These compounds are obtained by reacting a corresponding alkali metal 3-carbalkoxyphenylcyanoacetic ester with agents which introduce the radical R' at temperatures of between 70 and 150 DEG C. The compounds which are obtained can be used as intermediates for preparing pharmacologically active compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772708142 DE2708142C3 (en) | 1977-02-25 | 1977-02-25 | Process for the preparation of substituted phenylacetonitriles and new phenylacetonitriles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2381750A1 true FR2381750A1 (en) | 1978-09-22 |
Family
ID=6002131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7804716A Pending FR2381750A1 (en) | 1977-02-25 | 1978-02-20 | PHENYLACETONITRIL SUBSTITUTES AND THEIR PREPARATION |
Country Status (6)
| Country | Link |
|---|---|
| CH (1) | CH632236A5 (en) |
| DE (1) | DE2708142C3 (en) |
| ES (1) | ES462366A1 (en) |
| FR (1) | FR2381750A1 (en) |
| GR (1) | GR63096B (en) |
| YU (1) | YU136077A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE904238C (en) * | 1951-04-19 | 1954-02-15 | Oskar Willutzki | Steel lattice girder for concrete ceilings |
| KR100598271B1 (en) * | 1999-12-20 | 2006-07-07 | 에스케이 주식회사 | Method for preparing 3- (1-cyanoalkyl) benzoic acid |
| CN105130846A (en) * | 2015-07-27 | 2015-12-09 | 湖北仙盛科技有限公司 | Methyl 3-(cyanomethyl)benzoate synthetic method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5903M (en) * | 1966-07-13 | 1968-03-25 | ||
| DE2258985A1 (en) * | 1971-12-03 | 1973-06-14 | Rhone Poulenc Sa | PROCESS FOR THE MANUFACTURING OF 2- (3BENZOYLPHENYL) -PROPIONIC ACID AND ANALOGUE PRODUCTS |
| CH573386A5 (en) * | 1975-06-16 | 1976-03-15 | Juste Sa | Para-Isobutyl-phenyl-butyric acid prepn. - from corresp. acetonitrile cpd., having antiinflammatory, analgesic and antipyretic activity |
-
1977
- 1977-02-25 DE DE19772708142 patent/DE2708142C3/en not_active Expired
- 1977-05-28 GR GR53576A patent/GR63096B/en unknown
- 1977-06-01 YU YU136077A patent/YU136077A/en unknown
- 1977-09-14 ES ES462366A patent/ES462366A1/en not_active Expired
- 1977-12-13 CH CH1534477A patent/CH632236A5/en not_active IP Right Cessation
-
1978
- 1978-02-20 FR FR7804716A patent/FR2381750A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5903M (en) * | 1966-07-13 | 1968-03-25 | ||
| DE2258985A1 (en) * | 1971-12-03 | 1973-06-14 | Rhone Poulenc Sa | PROCESS FOR THE MANUFACTURING OF 2- (3BENZOYLPHENYL) -PROPIONIC ACID AND ANALOGUE PRODUCTS |
| CH573386A5 (en) * | 1975-06-16 | 1976-03-15 | Juste Sa | Para-Isobutyl-phenyl-butyric acid prepn. - from corresp. acetonitrile cpd., having antiinflammatory, analgesic and antipyretic activity |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2708142C3 (en) | 1981-10-29 |
| YU136077A (en) | 1982-08-31 |
| DE2708142B2 (en) | 1980-09-18 |
| DE2708142A1 (en) | 1978-08-31 |
| CH632236A5 (en) | 1982-09-30 |
| ES462366A1 (en) | 1978-06-01 |
| GR63096B (en) | 1979-08-14 |
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