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FR2378741A1 - GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES - Google Patents

GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES

Info

Publication number
FR2378741A1
FR2378741A1 FR7702959A FR7702959A FR2378741A1 FR 2378741 A1 FR2378741 A1 FR 2378741A1 FR 7702959 A FR7702959 A FR 7702959A FR 7702959 A FR7702959 A FR 7702959A FR 2378741 A1 FR2378741 A1 FR 2378741A1
Authority
FR
France
Prior art keywords
goxo
garyl
antiphlogistic
isovaleric acids
antalgic properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7702959A
Other languages
French (fr)
Other versions
FR2378741B1 (en
Inventor
Henri Cousse
Gilbert Mousin
Jean-Pierre Rieu
Et Jean-Pierre Tarayre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Priority to FR7702959A priority Critical patent/FR2378741A1/en
Priority to BE184536A priority patent/BE863196A/en
Priority to CA295,903A priority patent/CA1097684A/en
Priority to NL7801057A priority patent/NL7801057A/en
Priority to ES466493A priority patent/ES466493A1/en
Priority to CH110878A priority patent/CH628014A5/en
Priority to GB404378A priority patent/GB1565616A/en
Priority to DE19782804293 priority patent/DE2804293A1/en
Publication of FR2378741A1 publication Critical patent/FR2378741A1/en
Application granted granted Critical
Publication of FR2378741B1 publication Critical patent/FR2378741B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés chimiques nouveaux utiles comme médicaments et des compositions pharmaceutiques. Les nouveaux composés répondent à la formule générale :The invention relates to novel chemical compounds useful as medicaments and pharmaceutical compositions. The new compounds correspond to the general formula:

FR7702959A 1977-02-01 1977-02-01 GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES Granted FR2378741A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7702959A FR2378741A1 (en) 1977-02-01 1977-02-01 GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES
BE184536A BE863196A (en) 1977-02-01 1978-01-23 ALPHA ARYL ALPHA OXO ISOVALERIC ACIDS WITH ANTIPHOLOGISTIC AND ANTALGISTIC PROPERTIES
NL7801057A NL7801057A (en) 1977-02-01 1978-01-30 GAMMA-ARYL-GAMMA-OXO-ISOVALERIAN ACID DERIVATIVES AND METHOD FOR PREPARING THESE COMPOUNDS.
CA295,903A CA1097684A (en) 1977-02-01 1978-01-30 PROCESS FOR THE PREPARATION OF .gamma.ARYL .gamma.OXO ISOVALERIC ACIDS
ES466493A ES466493A1 (en) 1977-02-01 1978-01-31 4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing them
CH110878A CH628014A5 (en) 1977-02-01 1978-02-01 Gamma-aryl-gamma-oxoisovaleric acids having antiphlogistic and antalgic properties
GB404378A GB1565616A (en) 1977-02-01 1978-02-01 4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing them
DE19782804293 DE2804293A1 (en) 1977-02-01 1978-02-01 ALPHA-ARYL-GAMMA-OXO-ISOVALERIC ACID DERIVATIVES, THE METHOD FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7702959A FR2378741A1 (en) 1977-02-01 1977-02-01 GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES

Publications (2)

Publication Number Publication Date
FR2378741A1 true FR2378741A1 (en) 1978-08-25
FR2378741B1 FR2378741B1 (en) 1980-02-22

Family

ID=9186227

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7702959A Granted FR2378741A1 (en) 1977-02-01 1977-02-01 GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES

Country Status (8)

Country Link
BE (1) BE863196A (en)
CA (1) CA1097684A (en)
CH (1) CH628014A5 (en)
DE (1) DE2804293A1 (en)
ES (1) ES466493A1 (en)
FR (1) FR2378741A1 (en)
GB (1) GB1565616A (en)
NL (1) NL7801057A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS243570B1 (en) * 1984-08-31 1986-06-12 Miroslav Kuchar Omega-aryloxoalkane acids
IL115995A0 (en) * 1994-11-15 1996-01-31 Bayer Ag Substituted 4-biarylbutyric or 5-biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
US5886022A (en) * 1995-06-05 1999-03-23 Bayer Corporation Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
GB9522615D0 (en) * 1995-11-03 1996-01-03 Pharmacia Spa 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
US5863915A (en) * 1996-05-15 1999-01-26 Bayer Corporation Substituted 4-arylbutyric acid derivatives as matrix metalloprotease
ZA974033B (en) * 1996-05-15 1998-02-19 Bayer Ag Substituted 4-arylbutyric acid derivatives as matrix metalloprotease inhibitors.
CO5080759A1 (en) 1996-05-15 2001-09-25 Bayer Corp BIARILACETILENOS AS INHIBITORS OF THE METALOPROTEASE OF MATRIX

Also Published As

Publication number Publication date
GB1565616A (en) 1980-04-23
DE2804293C2 (en) 1989-08-03
CH628014A5 (en) 1982-02-15
BE863196A (en) 1978-05-16
NL7801057A (en) 1978-08-03
ES466493A1 (en) 1979-05-01
CA1097684A (en) 1981-03-17
FR2378741B1 (en) 1980-02-22
DE2804293A1 (en) 1978-08-10

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Legal Events

Date Code Title Description
ST Notification of lapse