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FR2374317A1 - Derives d'acide n-(benzothiazolyl-2)oxamique et procede pour leur preparation et leur utilisation comme medicament anti-allergique - Google Patents

Derives d'acide n-(benzothiazolyl-2)oxamique et procede pour leur preparation et leur utilisation comme medicament anti-allergique

Info

Publication number
FR2374317A1
FR2374317A1 FR7737467A FR7737467A FR2374317A1 FR 2374317 A1 FR2374317 A1 FR 2374317A1 FR 7737467 A FR7737467 A FR 7737467A FR 7737467 A FR7737467 A FR 7737467A FR 2374317 A1 FR2374317 A1 FR 2374317A1
Authority
FR
France
Prior art keywords
benzothiazolyl
acid derivatives
allergic
preparation
oxamic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7737467A
Other languages
English (en)
Other versions
FR2374317B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of FR2374317A1 publication Critical patent/FR2374317A1/fr
Application granted granted Critical
Publication of FR2374317B1 publication Critical patent/FR2374317B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention est relative à des dérivés d'acide N-(benzothiazolyl-2)oxamique répondant à la formule générale :
FR7737467A 1976-12-14 1977-12-13 Derives d'acide n-(benzothiazolyl-2)oxamique et procede pour leur preparation et leur utilisation comme medicament anti-allergique Granted FR2374317A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762656468 DE2656468A1 (de) 1976-12-14 1976-12-14 N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
FR2374317A1 true FR2374317A1 (fr) 1978-07-13
FR2374317B1 FR2374317B1 (fr) 1980-11-07

Family

ID=5995427

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7737467A Granted FR2374317A1 (fr) 1976-12-14 1977-12-13 Derives d'acide n-(benzothiazolyl-2)oxamique et procede pour leur preparation et leur utilisation comme medicament anti-allergique

Country Status (17)

Country Link
JP (1) JPS5377058A (fr)
AR (1) AR216496A1 (fr)
AT (1) AT360523B (fr)
AU (1) AU510730B2 (fr)
BE (1) BE861794A (fr)
CS (1) CS203179B2 (fr)
DD (1) DD133329A5 (fr)
DE (1) DE2656468A1 (fr)
ES (1) ES465034A1 (fr)
FI (1) FI57594C (fr)
FR (1) FR2374317A1 (fr)
GB (1) GB1538822A (fr)
HU (1) HU175340B (fr)
NL (1) NL7713580A (fr)
SE (1) SE7714074L (fr)
SU (1) SU680647A3 (fr)
ZA (1) ZA777236B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676775A (en) * 1949-10-24 1954-04-27 Gustav O Schulz Electric flatiron cord holder
DE3017976A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 2-amino-5-halogen-benzothiazole, verfahen zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4321372A (en) 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
DE3027527A1 (de) 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
GB2090826B (en) * 1981-01-09 1985-06-12 Usv Pharma Corp New heterocyclic compounds useful as anti-allergie agents
DE3135250A1 (de) * 1981-09-05 1983-03-17 Basf Ag, 6700 Ludwigshafen Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
KR100526487B1 (ko) 2000-06-21 2005-11-08 에프. 호프만-라 로슈 아게 벤조티아졸 유도체
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
EP1753760B1 (fr) 2004-05-24 2008-01-02 F.Hoffmann-La Roche Ag Acide 4-hydroxy-4-methyl-piperidine-1-carboxylique (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
EP1812392B1 (fr) 2004-11-05 2008-07-09 F.Hoffmann-La Roche Ag Procede pour preparer des derives d'acide isonicotinique
CN101180299B (zh) 2005-03-23 2010-12-15 弗·哈夫曼-拉罗切有限公司 作为mglur2拮抗剂的乙炔基-吡唑并嘧啶衍生物
BRPI0616571A2 (pt) 2005-09-27 2011-06-21 Hoffmann La Roche oxadiazolil pirazol-piridiminas como antagonistas de mglur2, processo para sua preparação, composição farmacêutica que os contém e uso dos mesmo

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2375222A1 (fr) * 1976-12-23 1978-07-21 Upjohn Co Nouveaux composes du type (2-benzothiazolyl)oxamate, leur procede de preparation et medicament les contenant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2375222A1 (fr) * 1976-12-23 1978-07-21 Upjohn Co Nouveaux composes du type (2-benzothiazolyl)oxamate, leur procede de preparation et medicament les contenant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1966 *

Also Published As

Publication number Publication date
AR216496A1 (es) 1979-12-28
GB1538822A (en) 1979-01-24
AT360523B (de) 1981-01-12
FI57594C (fi) 1980-09-10
ATA890777A (de) 1980-06-15
SU680647A3 (ru) 1979-08-15
JPS5377058A (en) 1978-07-08
BE861794A (fr) 1978-06-13
HU175340B (hu) 1980-07-28
ZA777236B (en) 1978-11-29
FI57594B (fi) 1980-05-30
SE7714074L (sv) 1978-06-15
DD133329A5 (de) 1978-12-27
AU510730B2 (en) 1980-07-10
DE2656468A1 (de) 1978-06-15
FR2374317B1 (fr) 1980-11-07
CS203179B2 (en) 1981-02-27
AU3137777A (en) 1979-06-14
FI773738A7 (fi) 1978-06-15
NL7713580A (nl) 1978-06-16
ES465034A1 (es) 1978-09-01

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Legal Events

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ST Notification of lapse