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FR2371442A1 - NEW COMPOUNDS USEFUL IN THE SYNTHESIS OF THROMBOXANE - Google Patents

NEW COMPOUNDS USEFUL IN THE SYNTHESIS OF THROMBOXANE

Info

Publication number
FR2371442A1
FR2371442A1 FR7805688A FR7805688A FR2371442A1 FR 2371442 A1 FR2371442 A1 FR 2371442A1 FR 7805688 A FR7805688 A FR 7805688A FR 7805688 A FR7805688 A FR 7805688A FR 2371442 A1 FR2371442 A1 FR 2371442A1
Authority
FR
France
Prior art keywords
thromboxane
synthesis
compounds useful
new compounds
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7805688A
Other languages
French (fr)
Other versions
FR2371442B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/676,894 external-priority patent/US4018804A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2371442A1 publication Critical patent/FR2371442A1/en
Application granted granted Critical
Publication of FR2371442B1 publication Critical patent/FR2371442B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne de nouveaux composés chimiques utiles dans la synthèse du thromboxane, ou analogues.The present invention relates to novel chemical compounds useful in the synthesis of thromboxane, or the like.

FR7805688A 1976-04-14 1978-02-28 NEW COMPOUNDS USEFUL IN THE SYNTHESIS OF THROMBOXANE Granted FR2371442A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/676,894 US4018804A (en) 1976-04-14 1976-04-14 Intermediate for synthesis of Thromboxane B2
US05/716,473 US4070384A (en) 1976-04-14 1976-08-20 Process for preparing thromboxane B compounds from prostaglandin fα co

Publications (2)

Publication Number Publication Date
FR2371442A1 true FR2371442A1 (en) 1978-06-16
FR2371442B1 FR2371442B1 (en) 1981-12-24

Family

ID=27101643

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7711306A Withdrawn FR2375185A1 (en) 1976-04-14 1977-04-14 NEW COMPOUNDS USEFUL IN THE SYNTHESIS OF THROMBOXANE
FR7805688A Granted FR2371442A1 (en) 1976-04-14 1978-02-28 NEW COMPOUNDS USEFUL IN THE SYNTHESIS OF THROMBOXANE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7711306A Withdrawn FR2375185A1 (en) 1976-04-14 1977-04-14 NEW COMPOUNDS USEFUL IN THE SYNTHESIS OF THROMBOXANE

Country Status (5)

Country Link
JP (1) JPS52136119A (en)
CH (1) CH633006A5 (en)
DE (1) DE2715883A1 (en)
FR (2) FR2375185A1 (en)
GB (1) GB1534982A (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TETRAHEDRON LETTERS, no. 37, septembre 1976, pages 3283-3286, Pergamon Press, Oxford (GB); W.P. SCHNEIDER et al.:"A synthesis of crystalline thromboxane B2 from a derivative of prostaglandin F2alpha1". *

Also Published As

Publication number Publication date
FR2371442B1 (en) 1981-12-24
GB1534982A (en) 1978-12-06
FR2375185A1 (en) 1978-07-21
JPS52136119A (en) 1977-11-14
DE2715883A1 (en) 1977-10-27
CH633006A5 (en) 1982-11-15

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Legal Events

Date Code Title Description
ST Notification of lapse