[go: up one dir, main page]

FR2369259A1 - Derives de 3,3-dichloro-2-azetidinone ayant une activite anti-inflammatoire - Google Patents

Derives de 3,3-dichloro-2-azetidinone ayant une activite anti-inflammatoire

Info

Publication number
FR2369259A1
FR2369259A1 FR7732304A FR7732304A FR2369259A1 FR 2369259 A1 FR2369259 A1 FR 2369259A1 FR 7732304 A FR7732304 A FR 7732304A FR 7732304 A FR7732304 A FR 7732304A FR 2369259 A1 FR2369259 A1 FR 2369259A1
Authority
FR
France
Prior art keywords
dichloro
inflammatory activity
azetidinone derivatives
azetidinone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7732304A
Other languages
English (en)
Inventor
John Krapcho
Chester F Turk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2369259A1 publication Critical patent/FR2369259A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des composés de formule :
FR7732304A 1976-11-01 1977-10-26 Derives de 3,3-dichloro-2-azetidinone ayant une activite anti-inflammatoire Withdrawn FR2369259A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/737,864 US4064120A (en) 1976-11-01 1976-11-01 3,3-Dichloro-2-azetidinone derivatives having antiinflammatory activity

Publications (1)

Publication Number Publication Date
FR2369259A1 true FR2369259A1 (fr) 1978-05-26

Family

ID=24965619

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7732304A Withdrawn FR2369259A1 (fr) 1976-11-01 1977-10-26 Derives de 3,3-dichloro-2-azetidinone ayant une activite anti-inflammatoire

Country Status (6)

Country Link
US (1) US4064120A (fr)
JP (1) JPS5356654A (fr)
CA (1) CA1088533A (fr)
DE (1) DE2748827A1 (fr)
FR (1) FR2369259A1 (fr)
GB (1) GB1571242A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2393793A1 (fr) * 1977-06-06 1979-01-05 Squibb & Sons Inc Derives de dichloro-3,3 azetidinones-2 a substituants basiques, leur procede de preparation et leur utilisation comme medicaments anti-inflammatoires

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174317A (en) * 1978-03-24 1979-11-13 E. R. Squibb & Sons, Inc. 3,3-Dichloro-2-azetidinone derivatives
US5229381A (en) * 1983-12-01 1993-07-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5229510A (en) * 1983-12-01 1993-07-20 Merck & Co., Inc. β-lactams useful in determining the amount of elastase in a clinical sample
US4680391A (en) * 1983-12-01 1987-07-14 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
JPH0647573B2 (ja) * 1984-08-29 1994-06-22 メクト株式会社 ２−アゼチジノン誘導体及びその製造方法
US5104862A (en) * 1991-03-20 1992-04-14 Merck & Co., Inc. Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5100880A (en) * 1991-03-20 1992-03-31 Merck & Co., Inc. Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5348953A (en) * 1991-06-25 1994-09-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
CA2147129A1 (fr) * 1992-10-27 1994-05-11 James B. Doherty Nouvelles azetidinones substituees utilisees comme agents anti-inflammatoires et anti-degeneratifs
US5591737A (en) * 1992-12-17 1997-01-07 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5747485A (en) * 1995-04-13 1998-05-05 Merck & Co., Inc. Substituted azetidiones as anti-inflammatory and antidegenerative agents

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3194801A (en) * 1962-10-15 1965-07-13 Lilly Co Eli Stable amino-substituted lactams

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3481920A (en) * 1965-10-22 1969-12-02 Lilly Co Eli Azetidinones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3194801A (en) * 1962-10-15 1965-07-13 Lilly Co Eli Stable amino-substituted lactams

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1976 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2393793A1 (fr) * 1977-06-06 1979-01-05 Squibb & Sons Inc Derives de dichloro-3,3 azetidinones-2 a substituants basiques, leur procede de preparation et leur utilisation comme medicaments anti-inflammatoires

Also Published As

Publication number Publication date
CA1088533A (fr) 1980-10-28
JPS5356654A (en) 1978-05-23
DE2748827A1 (de) 1978-05-03
US4064120A (en) 1977-12-20
GB1571242A (en) 1980-07-09

Similar Documents

Publication Publication Date Title
FR2383171A1 (fr) Derives de thiopropanoylaminoacides utiles comme hypotenseurs
FR2453145A1 (fr)
FR2364198A1 (fr) Nouveaux produits a action herbicide, derives d'acides phenoxyvaleriques
FR2357553A1 (fr) Procede de preparation de benzothiazoles
FR2361892A1 (fr) Esters et amides des acides pyrimido(4,5-b)quinolein-4(3h)-one-2-carboxyliques, en tant qu'agents anti-ulceres
FR2389629A1 (fr)
FR2372817A1 (fr) Derives d'acides thiazolidinecarboxyliques et d'acides apparentes, utiles comme agents anti-hypertension
FR2369259A1 (fr) Derives de 3,3-dichloro-2-azetidinone ayant une activite anti-inflammatoire
FR2384745A1 (fr) Derives de la somatostatine et leur preparation
FR2375239A1 (fr) Derives d'acide 7-amino-8-oxo-3-oxa-1-azabicyclo-(4.2.0)octane-2-carboxylique
FR2373546A1 (fr) Derives thio-oxime de cephalosporines et de penicillines, utiles comme inhibiteurs de b-lactamases
FR2361366A1 (fr) Derives heterocycliques de la guanidine
FR2383931A1 (fr) Derives d'oxadiazolopyrimidine
FR2368277A1 (fr) Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique
FR2357558A1 (fr) 2,6-methano-2h-1-benzoxocines
FR2389597A1 (fr)
FR2367761A1 (fr) Derives piperidylideniques de benzo-xanthenes,
FR2359111A1 (fr) Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques utiles comme herbicides
FR2377999A1 (fr) Nouveaux derives de cycloalcanecarboxanilide a activite herbicide
FR2372839A1 (fr) Derives d'oxazolidinedione des alcaloides de vinca, a activite antitumorale
FR2446284A1 (fr) Tetrahydro-benzo(c)quinoleine-9(8h)ones
FR2389631A1 (fr)
FR2446835A1 (fr) Octahydro-2h-pyrrolo(3,4-g)quinoleines utiles comme intermediaires
FR2398752A1 (fr) Esters tetracarboxyliques de 2,2,6,6-tetramethyl-piperidino-spiro-dioxanol
FR2372784A1 (fr) Derives aldehydiques de cyclopentane utiles comme agents odoriferants

Legal Events

Date Code Title Description
ST Notification of lapse