FR2364059A1 - Conversion of liquids or solids into solid adsorbates - for prepn. of solid pharmaceutical compsns. - Google Patents
Conversion of liquids or solids into solid adsorbates - for prepn. of solid pharmaceutical compsns.Info
- Publication number
- FR2364059A1 FR2364059A1 FR7627020A FR7627020A FR2364059A1 FR 2364059 A1 FR2364059 A1 FR 2364059A1 FR 7627020 A FR7627020 A FR 7627020A FR 7627020 A FR7627020 A FR 7627020A FR 2364059 A1 FR2364059 A1 FR 2364059A1
- Authority
- FR
- France
- Prior art keywords
- solid
- solvent
- conversion
- solids
- prepn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000007787 solid Substances 0.000 title abstract 7
- 239000007788 liquid Substances 0.000 title abstract 3
- 239000002156 adsorbate Substances 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 title abstract 2
- 239000002904 solvent Substances 0.000 abstract 4
- 239000000126 substance Substances 0.000 abstract 3
- 239000003463 adsorbent Substances 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000019155 vitamin A Nutrition 0.000 abstract 1
- 239000011719 vitamin A Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/2803—Sorbents comprising a binder, e.g. for forming aggregated, agglomerated or granulated products
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Conversion of one or more liquid or solid substances into a solid adsorbate on one or more adsorbents is claimed in which a non-solvent cpd. for the substance is added to a suspension or soln. of the adsorbent in a solvent contg. the substance to be adsorbed, the solvent being miscible with the non-solvent cpd. Used esp. for converting liquid active principles or excipients into substantially homogeneous solids which may be converted into conventionally solid pharmaceutical compsns., e.g. by granulation, tabletting, coating, etc. Typically, vitamins A and D2 were dissolved in water and carboxymethylcellulose was added. The suspension was stirred until quasi-homogeneous and spray-dried using N2 to give a fine powder with quantitative recovery of vitamins.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7627020A FR2364059A1 (en) | 1976-09-08 | 1976-09-08 | Conversion of liquids or solids into solid adsorbates - for prepn. of solid pharmaceutical compsns. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7627020A FR2364059A1 (en) | 1976-09-08 | 1976-09-08 | Conversion of liquids or solids into solid adsorbates - for prepn. of solid pharmaceutical compsns. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2364059A1 true FR2364059A1 (en) | 1978-04-07 |
Family
ID=9177483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7627020A Withdrawn FR2364059A1 (en) | 1976-09-08 | 1976-09-08 | Conversion of liquids or solids into solid adsorbates - for prepn. of solid pharmaceutical compsns. |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2364059A1 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0192460A3 (en) * | 1985-02-19 | 1988-01-27 | Dynagran Corporation Of America | Quick-liquifying chewable tablet |
| EP0275819A3 (en) * | 1986-12-22 | 1989-01-11 | Max Stricker | Labyrinth-type filter for the dielectric fluid of electro-discharge machines |
| EP0400910A3 (en) * | 1989-05-30 | 1992-09-16 | F.H. FAULDING & CO. LTD. | Shaped articles containing liquefiable powders for delivery of cosmetic and other personal care agents |
| FR2721512A1 (en) * | 1994-06-28 | 1995-12-29 | Maurice Jacob | Formulation and process for the preparation of spheroids based on solutions of vegetable origin |
| FR2741533A1 (en) * | 1995-11-28 | 1997-05-30 | Grinda Jean Robert | New process to stabilise poly-unsaturated fatty acids for cosmetic use |
| CN108393071A (en) * | 2018-03-21 | 2018-08-14 | 广东电网有限责任公司电力科学研究院 | A kind of compound adsorbent and preparation method thereof |
-
1976
- 1976-09-08 FR FR7627020A patent/FR2364059A1/en not_active Withdrawn
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0192460A3 (en) * | 1985-02-19 | 1988-01-27 | Dynagran Corporation Of America | Quick-liquifying chewable tablet |
| EP0275819A3 (en) * | 1986-12-22 | 1989-01-11 | Max Stricker | Labyrinth-type filter for the dielectric fluid of electro-discharge machines |
| EP0400910A3 (en) * | 1989-05-30 | 1992-09-16 | F.H. FAULDING & CO. LTD. | Shaped articles containing liquefiable powders for delivery of cosmetic and other personal care agents |
| FR2721512A1 (en) * | 1994-06-28 | 1995-12-29 | Maurice Jacob | Formulation and process for the preparation of spheroids based on solutions of vegetable origin |
| EP0689833A3 (en) * | 1994-06-28 | 1997-04-16 | Maurice Jacob | Process for preparing natural actives containing spheroids, especially of vegetable origin, and spheroids thus obtained |
| FR2741533A1 (en) * | 1995-11-28 | 1997-05-30 | Grinda Jean Robert | New process to stabilise poly-unsaturated fatty acids for cosmetic use |
| CN108393071A (en) * | 2018-03-21 | 2018-08-14 | 广东电网有限责任公司电力科学研究院 | A kind of compound adsorbent and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |