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FR2356423A1 - Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids - prepd. by (N)-acylating the (N)-unsubstd. cpds. - Google Patents

Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids - prepd. by (N)-acylating the (N)-unsubstd. cpds.

Info

Publication number
FR2356423A1
FR2356423A1 FR7620068A FR7620068A FR2356423A1 FR 2356423 A1 FR2356423 A1 FR 2356423A1 FR 7620068 A FR7620068 A FR 7620068A FR 7620068 A FR7620068 A FR 7620068A FR 2356423 A1 FR2356423 A1 FR 2356423A1
Authority
FR
France
Prior art keywords
unsubstd
prepd
cpds
thiazolidine
acylating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7620068A
Other languages
French (fr)
Other versions
FR2356423B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7620068A priority Critical patent/FR2356423A1/en
Priority to DE19772729414 priority patent/DE2729414A1/en
Publication of FR2356423A1 publication Critical patent/FR2356423A1/en
Application granted granted Critical
Publication of FR2356423B1 publication Critical patent/FR2356423B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New thiazolidine carboxylic acid derivs. are of formula (I) (where R1 is 2-17C alkanoyl; and R2 is carboxy or one of its functional derivs. i.e. an ester or amide gp. or an inorganic (esp. alkali(ne earth)) or organic (esp. amine) salt of the carboxy gp). (I), their optical isomers and acceptable acid addn. salts are useful for treating kidney, liver and gallstones, in that they are capable of bringing about dissolution of oxalate, phosphate, uric acid, cystine, etc. accretions. In addn., they are also useful for treating metabolic disorders; this is because they introduce biological sulphur into the organism, where it has a plastic, energetic and protective effect. (I) can also be used in veterinary medicine, e.g. to increase the wt. of piglets, foals, etc. and to reduce their mortality during the first 56 days of life.
FR7620068A 1976-07-01 1976-07-01 Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids - prepd. by (N)-acylating the (N)-unsubstd. cpds. Granted FR2356423A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7620068A FR2356423A1 (en) 1976-07-01 1976-07-01 Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids - prepd. by (N)-acylating the (N)-unsubstd. cpds.
DE19772729414 DE2729414A1 (en) 1976-07-01 1977-06-29 THIAZOLIDINE CARBONIC ACID DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7620068A FR2356423A1 (en) 1976-07-01 1976-07-01 Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids - prepd. by (N)-acylating the (N)-unsubstd. cpds.

Publications (2)

Publication Number Publication Date
FR2356423A1 true FR2356423A1 (en) 1978-01-27
FR2356423B1 FR2356423B1 (en) 1978-12-15

Family

ID=9175106

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7620068A Granted FR2356423A1 (en) 1976-07-01 1976-07-01 Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids - prepd. by (N)-acylating the (N)-unsubstd. cpds.

Country Status (2)

Country Link
DE (1) DE2729414A1 (en)
FR (1) FR2356423A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421889A1 (en) * 1978-04-08 1979-11-02 Santen Pharmaceutical Co Ltd NEW DERIVATIVES OF THIAZOLIDINECARBOXYLIC-4 ACID USEFUL AS ANTIHYPERTENSIVE MEDICINAL PRODUCTS AND METHODS FOR THEIR PREPARATION
FR2439197A1 (en) * 1978-10-16 1980-05-16 Lilly Co Eli 1-THIA-3-AZA-4-ONES, SUBSTITUTED, THEIR PREPARATION AND THEIR USE IN AGRICULTURE
EP0062612A1 (en) * 1981-04-02 1982-10-13 Ciba-Geigy Ag Thiazoline derivatives
EP0279681A3 (en) * 1987-02-20 1989-11-15 Yamanouchi Pharmaceutical Co. Ltd. Saturated heterocyclic carboxamide derivatives

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482712A (en) * 1978-10-16 1984-11-13 Eli Lilly And Company Substituted 1-thia-3-aza-4-ones
US4436739A (en) 1978-10-16 1984-03-13 Eli Lilly And Company Substituted 1-thia-3-aza-4-ones
DE3170401D1 (en) 1980-07-28 1985-06-13 Ciba Geigy Ag Triazoline derivatives and processes for their preparation
HU200177B (en) * 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
CN102917685B (en) 2010-05-28 2015-11-25 味之素株式会社 Cysteine derivative

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421889A1 (en) * 1978-04-08 1979-11-02 Santen Pharmaceutical Co Ltd NEW DERIVATIVES OF THIAZOLIDINECARBOXYLIC-4 ACID USEFUL AS ANTIHYPERTENSIVE MEDICINAL PRODUCTS AND METHODS FOR THEIR PREPARATION
FR2439197A1 (en) * 1978-10-16 1980-05-16 Lilly Co Eli 1-THIA-3-AZA-4-ONES, SUBSTITUTED, THEIR PREPARATION AND THEIR USE IN AGRICULTURE
EP0062612A1 (en) * 1981-04-02 1982-10-13 Ciba-Geigy Ag Thiazoline derivatives
EP0279681A3 (en) * 1987-02-20 1989-11-15 Yamanouchi Pharmaceutical Co. Ltd. Saturated heterocyclic carboxamide derivatives

Also Published As

Publication number Publication date
DE2729414A1 (en) 1978-01-05
FR2356423B1 (en) 1978-12-15

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