FR2295753A1 - Topical acetylsalicylic acid compsns. - contg. as vehicle an inert, hydrophilic lipophilic penetrant - Google Patents
Topical acetylsalicylic acid compsns. - contg. as vehicle an inert, hydrophilic lipophilic penetrantInfo
- Publication number
- FR2295753A1 FR2295753A1 FR7442596A FR7442596A FR2295753A1 FR 2295753 A1 FR2295753 A1 FR 2295753A1 FR 7442596 A FR7442596 A FR 7442596A FR 7442596 A FR7442596 A FR 7442596A FR 2295753 A1 FR2295753 A1 FR 2295753A1
- Authority
- FR
- France
- Prior art keywords
- inert
- penetrant
- vehicle
- acetylsalicylic acid
- topical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001138 acetylsalicylic acid Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compsn. for topical application comprises 1-25 wt.% acetylsalicylic acid (I), pref. of particle size 20 mu, and 75-99 wt.% of a therapeutically-inert, hydrophilic lipophilic penetrant vehicle (II), esp. one which, in a 25% (I) compsn., permits the absorption of 100-1000 ug. (I) per cm.2 of skin in is not >=3 min. (I) is a well-known antipyretic, analgesic and antirheumatic. In this form (I) acts more rapidly than when given orally or rectally and the side effects of oral ingestion are avoided.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7442596A FR2295753A1 (en) | 1974-12-23 | 1974-12-23 | Topical acetylsalicylic acid compsns. - contg. as vehicle an inert, hydrophilic lipophilic penetrant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7442596A FR2295753A1 (en) | 1974-12-23 | 1974-12-23 | Topical acetylsalicylic acid compsns. - contg. as vehicle an inert, hydrophilic lipophilic penetrant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2295753A1 true FR2295753A1 (en) | 1976-07-23 |
Family
ID=9146534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7442596A Withdrawn FR2295753A1 (en) | 1974-12-23 | 1974-12-23 | Topical acetylsalicylic acid compsns. - contg. as vehicle an inert, hydrophilic lipophilic penetrant |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2295753A1 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2496459A1 (en) * | 1980-12-19 | 1982-06-25 | Astier Laboratoires Docteur P | PHARMACEUTICAL COMPOSITION IN THE FORM OF A GEL CONTAINING ACETYLSALICYLIC ACID |
| WO1992020343A1 (en) * | 1991-04-03 | 1992-11-26 | Gunderson Medical Foundation, Ltd. | Suppression of thromboxane levels by percutaneous administration of aspirin |
| US5240917A (en) * | 1991-04-03 | 1993-08-31 | Keimowitz Rudolph M | Suppression of thromboxane levels by percutaneous administration of aspirin |
| WO1994013302A1 (en) * | 1991-12-20 | 1994-06-23 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal administration system containing acetylsalicylic acid for antithrombotic therapy and the prevention of cancer |
| US6071896A (en) * | 1992-06-16 | 2000-06-06 | Gundersen Clinic, Ltd. | Suppression of thromboxane levels by percutaneous administration of aspirin |
| WO2001003774A3 (en) * | 1999-07-07 | 2002-03-21 | Zoltan Dardai | Pharmaceutical composition for the treatment of calcification |
-
1974
- 1974-12-23 FR FR7442596A patent/FR2295753A1/en not_active Withdrawn
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2496459A1 (en) * | 1980-12-19 | 1982-06-25 | Astier Laboratoires Docteur P | PHARMACEUTICAL COMPOSITION IN THE FORM OF A GEL CONTAINING ACETYLSALICYLIC ACID |
| EP0055635A1 (en) * | 1980-12-19 | 1982-07-07 | Laboratoires du Docteur P. ASTIER | Pharmaceutical composition with acetylsalicylic acid in gel form |
| WO1992020343A1 (en) * | 1991-04-03 | 1992-11-26 | Gunderson Medical Foundation, Ltd. | Suppression of thromboxane levels by percutaneous administration of aspirin |
| US5240917A (en) * | 1991-04-03 | 1993-08-31 | Keimowitz Rudolph M | Suppression of thromboxane levels by percutaneous administration of aspirin |
| US5763425A (en) * | 1991-04-03 | 1998-06-09 | Gundersen Clinic, Ltd. | Suppression of thromboxane levels by percutaneous administration of aspirin |
| WO1994013302A1 (en) * | 1991-12-20 | 1994-06-23 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal administration system containing acetylsalicylic acid for antithrombotic therapy and the prevention of cancer |
| US6071896A (en) * | 1992-06-16 | 2000-06-06 | Gundersen Clinic, Ltd. | Suppression of thromboxane levels by percutaneous administration of aspirin |
| WO2001003774A3 (en) * | 1999-07-07 | 2002-03-21 | Zoltan Dardai | Pharmaceutical composition for the treatment of calcification |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |