FR2295015A1 - Procede de preparation d'esters alkyliques inferieurs d'a-l-aspartyl l-phenylalanine - Google Patents
Procede de preparation d'esters alkyliques inferieurs d'a-l-aspartyl l-phenylalanineInfo
- Publication number
- FR2295015A1 FR2295015A1 FR7441816A FR7441816A FR2295015A1 FR 2295015 A1 FR2295015 A1 FR 2295015A1 FR 7441816 A FR7441816 A FR 7441816A FR 7441816 A FR7441816 A FR 7441816A FR 2295015 A1 FR2295015 A1 FR 2295015A1
- Authority
- FR
- France
- Prior art keywords
- lower alkyl
- phenylalanine
- mole
- alpha
- methyl ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000005907 alkyl ester group Chemical group 0.000 title abstract 3
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 title abstract 2
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 title abstract 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 title abstract 2
- 229960005261 aspartic acid Drugs 0.000 title abstract 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 title 2
- 229960005190 phenylalanine Drugs 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- VSDUZFOSJDMAFZ-VIFPVBQESA-N methyl L-phenylalaninate Chemical compound COC(=O)[C@@H](N)CC1=CC=CC=C1 VSDUZFOSJDMAFZ-VIFPVBQESA-N 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- -1 alkyl sulphate Chemical compound 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7441816A FR2295015A1 (fr) | 1974-12-18 | 1974-12-18 | Procede de preparation d'esters alkyliques inferieurs d'a-l-aspartyl l-phenylalanine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7441816A FR2295015A1 (fr) | 1974-12-18 | 1974-12-18 | Procede de preparation d'esters alkyliques inferieurs d'a-l-aspartyl l-phenylalanine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2295015A1 true FR2295015A1 (fr) | 1976-07-16 |
| FR2295015B1 FR2295015B1 (fr) | 1979-06-08 |
Family
ID=9146353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7441816A Granted FR2295015A1 (fr) | 1974-12-18 | 1974-12-18 | Procede de preparation d'esters alkyliques inferieurs d'a-l-aspartyl l-phenylalanine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2295015A1 (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549068A1 (fr) * | 1983-06-27 | 1985-01-18 | Besins Jean | Procede de preparation de dipeptides derives de l'acide aspartique et produit obtenu par la mise en oeuvre de ce procede |
| EP0466963A1 (fr) * | 1988-07-14 | 1992-01-22 | The Nutrasweet Company | Procédé pour la préparation de l'alpha-L-aspartyl-L-phénylalanineméthylester utilisant de l'anhydride N-formylaspartique isolée |
| EP0468063A1 (fr) * | 1988-02-12 | 1992-01-29 | The Nutrasweet Company | Procédé en une étape pour la préparation de l'ester méthylique de l'alpha-L-aspartyl-L-phénylalanine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2145979A6 (fr) * | 1971-07-09 | 1973-02-23 | Ajinomoto Kk |
-
1974
- 1974-12-18 FR FR7441816A patent/FR2295015A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2145979A6 (fr) * | 1971-07-09 | 1973-02-23 | Ajinomoto Kk |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549068A1 (fr) * | 1983-06-27 | 1985-01-18 | Besins Jean | Procede de preparation de dipeptides derives de l'acide aspartique et produit obtenu par la mise en oeuvre de ce procede |
| EP0468063A1 (fr) * | 1988-02-12 | 1992-01-29 | The Nutrasweet Company | Procédé en une étape pour la préparation de l'ester méthylique de l'alpha-L-aspartyl-L-phénylalanine |
| EP0466963A1 (fr) * | 1988-07-14 | 1992-01-22 | The Nutrasweet Company | Procédé pour la préparation de l'alpha-L-aspartyl-L-phénylalanineméthylester utilisant de l'anhydride N-formylaspartique isolée |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2295015B1 (fr) | 1979-06-08 |
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