FR2253522B1 - - Google Patents
Info
- Publication number
- FR2253522B1 FR2253522B1 FR7440041A FR7440041A FR2253522B1 FR 2253522 B1 FR2253522 B1 FR 2253522B1 FR 7440041 A FR7440041 A FR 7440041A FR 7440041 A FR7440041 A FR 7440041A FR 2253522 B1 FR2253522 B1 FR 2253522B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2361390A DE2361390A1 (de) | 1973-12-10 | 1973-12-10 | Isochinolinderivate und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2253522A1 FR2253522A1 (fr) | 1975-07-04 |
| FR2253522B1 true FR2253522B1 (fr) | 1978-06-30 |
Family
ID=5900348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7440041A Expired FR2253522B1 (fr) | 1973-12-10 | 1974-12-06 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3985881A (fr) |
| JP (1) | JPS5088077A (fr) |
| AT (1) | AT351026B (fr) |
| BE (1) | BE823027A (fr) |
| CA (1) | CA1053675A (fr) |
| CH (1) | CH605776A5 (fr) |
| CS (1) | CS188933B2 (fr) |
| DD (1) | DD115666A5 (fr) |
| DE (1) | DE2361390A1 (fr) |
| DK (1) | DK137007C (fr) |
| ES (1) | ES432716A1 (fr) |
| FR (1) | FR2253522B1 (fr) |
| GB (1) | GB1447611A (fr) |
| HU (1) | HU171483B (fr) |
| IL (1) | IL46160A0 (fr) |
| NL (1) | NL7416050A (fr) |
| SE (1) | SE7415247L (fr) |
| ZA (1) | ZA747820B (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
| US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
| US4556712A (en) * | 1981-05-20 | 1985-12-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| DE3713743A1 (de) * | 1987-04-24 | 1988-11-17 | Boehringer Ingelheim Kg | Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
| PT89780A (pt) * | 1988-02-23 | 1989-10-04 | Glaxo Group Ltd | Processo para a preparacao de derivados da tetrahidroisoquinolina |
| DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
| GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
| US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
| GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| US9604930B2 (en) * | 2012-12-21 | 2017-03-28 | Epizyme, Inc. | Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof |
| AU2016316436B2 (en) * | 2015-09-01 | 2021-04-29 | Merck Patent Gmbh | Method for the production of praziquantel and precursors thereof |
| CA3001857A1 (fr) * | 2015-10-14 | 2017-04-20 | Aquinnah Pharmaceuticals, Inc. | Composes, compositions et methodes d'utilisation contre des granules de stress |
| IL273428B2 (en) | 2017-09-22 | 2023-09-01 | Jubilant Epipad LLC | Heterocyclic compounds as pad inhibitors |
| CN111225915B (zh) | 2017-10-18 | 2023-03-07 | 朱比兰特埃皮帕德有限公司 | 作为pad抑制剂的咪唑并吡啶化合物 |
| BR112020008851A2 (pt) | 2017-11-06 | 2020-10-20 | Jubilant Prodel LLC | composto da fórmula i, processo de preparação de compostos da fórmula i, composição farmacêutica, método para o tratamento e/ou prevenção de várias doenças, uso, método para o tratamento de câncer, método de tratamento de câncer e método para o tratamento e/ou prevenção de câncer e doenças infecciosas |
| JP7368369B2 (ja) | 2017-11-24 | 2023-10-24 | ジュビラント・エピスクライブ・エルエルシー | Prmt5阻害剤としてのヘテロ環式化合物 |
| JP7279063B6 (ja) | 2018-03-13 | 2024-02-15 | ジュビラント プローデル エルエルシー | Pd1/pd-l1相互作用/活性化の阻害剤としての二環式化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2612503A (en) * | 1949-04-19 | 1952-09-30 | Smith Kline French Lab | Basic ether-substituted isoquinolines |
| US2640829A (en) * | 1950-11-10 | 1953-06-02 | Smith Kline French Lab | Isoquinolyl heterocyclic ethers |
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| US3483206A (en) * | 1967-12-15 | 1969-12-09 | Ciba Geigy Corp | N-isoquinolylalkanoyl-n-arylamines |
| US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
-
1973
- 1973-12-10 DE DE2361390A patent/DE2361390A1/de active Pending
-
1974
- 1974-11-29 IL IL46160A patent/IL46160A0/xx unknown
- 1974-12-05 SE SE7415247A patent/SE7415247L/xx unknown
- 1974-12-06 FR FR7440041A patent/FR2253522B1/fr not_active Expired
- 1974-12-06 CA CA215,386A patent/CA1053675A/fr not_active Expired
- 1974-12-06 BE BE151221A patent/BE823027A/fr unknown
- 1974-12-06 CS CS748365A patent/CS188933B2/cs unknown
- 1974-12-09 US US05/530,551 patent/US3985881A/en not_active Expired - Lifetime
- 1974-12-09 DK DK639674A patent/DK137007C/da active
- 1974-12-09 JP JP49141945A patent/JPS5088077A/ja active Pending
- 1974-12-09 DD DD182514A patent/DD115666A5/xx unknown
- 1974-12-09 ES ES432716A patent/ES432716A1/es not_active Expired
- 1974-12-09 CH CH1632774A patent/CH605776A5/xx not_active IP Right Cessation
- 1974-12-09 HU HU74ME00001812A patent/HU171483B/hu unknown
- 1974-12-09 AT AT981974A patent/AT351026B/de not_active IP Right Cessation
- 1974-12-09 ZA ZA00747820A patent/ZA747820B/xx unknown
- 1974-12-09 GB GB5319174A patent/GB1447611A/en not_active Expired
- 1974-12-10 NL NL7416050A patent/NL7416050A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK137007C (da) | 1978-06-05 |
| GB1447611A (en) | 1976-08-25 |
| CS188933B2 (en) | 1979-03-30 |
| CH605776A5 (fr) | 1978-10-13 |
| JPS5088077A (fr) | 1975-07-15 |
| DK639674A (fr) | 1975-08-11 |
| HU171483B (hu) | 1978-01-28 |
| NL7416050A (nl) | 1975-06-12 |
| US3985881A (en) | 1976-10-12 |
| BE823027A (fr) | 1975-06-06 |
| DK137007B (da) | 1978-01-02 |
| FR2253522A1 (fr) | 1975-07-04 |
| ZA747820B (en) | 1975-12-31 |
| IL46160A0 (en) | 1975-02-10 |
| AU7625774A (en) | 1976-06-10 |
| PL93405B1 (fr) | 1977-05-30 |
| AT351026B (de) | 1979-07-10 |
| DE2361390A1 (de) | 1975-06-19 |
| CA1053675A (fr) | 1979-05-01 |
| ATA981974A (de) | 1978-12-15 |
| SE7415247L (fr) | 1975-06-11 |
| DD115666A5 (fr) | 1975-10-12 |
| ES432716A1 (es) | 1977-03-01 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |