FR21C1050I1 - Formes cristallines d'un modulateur de récepteur d'androgène - Google Patents

Formes cristallines d'un modulateur de récepteur d'androgène

Info

Publication number: FR21C1050I1
Authority: FR; France
Prior art keywords: androgen receptor; crystalline forms; receptor modulator; modulator; androgen
Prior art date: 2012-06-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

FR21C1050C

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Memorial Sloan Kettering Cancer Center

Aragon Pharmaceuticals Inc

Original Assignee

Memorial Sloan Kettering Cancer Center

Aragon Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-06-07

Filing date

2021-11-03

Publication date

2021-12-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49712550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR21C1050(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2021-11-03 Application filed by Memorial Sloan Kettering Cancer Center, Aragon Pharmaceuticals Inc filed Critical Memorial Sloan Kettering Cancer Center

2021-12-10 Publication of FR21C1050I1 publication Critical patent/FR21C1050I1/fr

2024-05-24 Application granted granted Critical

2024-05-24 Publication of FR21C1050I2 publication Critical patent/FR21C1050I2/fr

Status Active legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

FR21C1050C 2012-06-07 2021-11-03 Formes cristallines d'un modulateur de récepteur d'androgène Active FR21C1050I2 (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201261656888P	2012-06-07	2012-06-07
PCT/US2013/044116 WO2013184681A1 (fr)	2012-06-07	2013-06-04	Formes cristallines d'un modulateur du récepteur des androgènes
EP13800681.2A EP2858985B1 (fr)	2012-06-07	2013-06-04	Formes cristallines d'un modulateur du récepteur des androgènes
EP18157435.1A EP3348553B1 (fr)	2012-06-07	2013-06-04	Formes cristallines d'un modulateur de récepteur d'androgène

Publications (2)

Publication Number	Publication Date
FR21C1050I1 true FR21C1050I1 (fr)	2021-12-10
FR21C1050I2 FR21C1050I2 (fr)	2024-05-24

Family

ID=49712550

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR21C1050C Active FR21C1050I2 (fr)	2012-06-07	2021-11-03	Formes cristallines d'un modulateur de récepteur d'androgène

Country Status (45)

Country	Link
US (9)	US9481663B2 (fr)
EP (4)	EP3348553B1 (fr)
JP (3)	JP6182209B2 (fr)
KR (2)	KR102062024B1 (fr)
CN (3)	CN113135892A (fr)
AU (3)	AU2013271751B2 (fr)
BR (1)	BR112014030678A2 (fr)
CA (4)	CA3114726A1 (fr)
CL (1)	CL2014003331A1 (fr)
CO (1)	CO7240407A2 (fr)
CR (2)	CR20190331A (fr)
CY (4)	CY1120393T1 (fr)
DK (3)	DK3348553T3 (fr)
EA (3)	EA028791B1 (fr)
EC (1)	ECSP14030098A (fr)
ES (3)	ES2809738T3 (fr)
FR (1)	FR21C1050I2 (fr)
GT (1)	GT201400283A (fr)
HK (2)	HK1210175A1 (fr)
HR (3)	HRP20180902T1 (fr)
HU (4)	HUE038082T2 (fr)
IL (5)	IL320522A (fr)
IN (1)	IN2014DN10084A (fr)
LT (4)	LT3533792T (fr)
LU (1)	LUC00236I2 (fr)
ME (2)	ME03815B (fr)
MX (1)	MX356754B (fr)
MY (1)	MY187500A (fr)
NI (1)	NI201400142A (fr)
NL (1)	NL301144I2 (fr)
NO (1)	NO2021046I1 (fr)
NZ (2)	NZ702203A (fr)
PE (3)	PE20200725A1 (fr)
PH (2)	PH12014502714B1 (fr)
PL (3)	PL2858985T3 (fr)
PT (3)	PT2858985T (fr)
RS (3)	RS61988B1 (fr)
SG (3)	SG10201610249TA (fr)
SI (3)	SI3533792T1 (fr)
SM (3)	SMT201800311T1 (fr)
TR (1)	TR201808939T4 (fr)
TW (1)	TWI532732B (fr)
UA (2)	UA115665C2 (fr)
WO (1)	WO2013184681A1 (fr)
ZA (1)	ZA201500076B (fr)

Families Citing this family (29)

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WO2008119015A2 (fr)	2007-03-27	2008-10-02	Sloan-Kettering Institute For Cancer Research	Synthèse de dérivés de la thiohydantoïne
PE20150099A1 (es)	2011-12-16	2015-01-30	Olema Pharmaceuticals Inc	Compuestos novedosos de benzopirano, composiciones y usos de los mismos
ES2809738T3 (es)	2012-06-07	2021-03-05	Aragon Pharmaceuticals Inc	Formas cristalinas de un modulador de receptor de andrógenos
WO2014043208A1 (fr)	2012-09-11	2014-03-20	Medivation Prostate Therapeutics, Inc.	Formulations d'enzalutamide
PT3305285T (pt)	2012-09-26	2020-11-24	Aragon Pharmaceuticals Inc	Antiandrogénios para o tratamento de cancro da próstata resistente à castração não metastático
JOP20200097A1 (ar)	2013-01-15	2017-06-16	Aragon Pharmaceuticals Inc	معدل مستقبل أندروجين واستخداماته
CN106795152B (zh) *	2014-08-26	2020-01-31	安斯达尔生物技术有限责任公司	蛋白激酶抑制剂
CR20170217A (es)	2014-12-05	2017-08-30	Aragon Pharmaceuticals Inc	Composiciones anticancerígenas
CA2969675C (fr)	2014-12-05	2023-06-06	Aragon Pharmaceuticals, Inc.	Compositions anticancereuses
BR112017011788A2 (pt)	2014-12-05	2017-12-26	Aragon Pharmaceuticals Inc	composições anticâncer
WO2016100905A1 (fr)	2014-12-19	2016-06-23	Lutron Electronics Co., Inc.	Appareil d'éclairage multicanal comportant de multiples pilotes de diode électroluminescente
TW201808287A (zh)	2016-06-03	2018-03-16	美商艾瑞岡醫藥公司	抗癌組成物
ES2952770T3 (es)	2016-12-13	2023-11-06	Watson Lab Inc	Formas de estado sólido de apalutamida
EP4438126A3 (fr)	2017-10-16	2025-01-01	Aragon Pharmaceuticals, Inc.	Anti-androgènes pour le traitement du cancer de la prostate résistant à la castration non métastatique
WO2019135254A1 (fr)	2018-01-02	2019-07-11	Mylan Laboratories Limited	Polymorphes d'apalutamide et leur préparation
WO2019242439A1 (fr) *	2018-06-20	2019-12-26	苏州科睿思制药有限公司	Formes cristallines de l'arn-509, procédé de préparation correspondant et utilisation associée
WO2020049598A2 (fr)	2018-09-08	2020-03-12	Cipla Limited	Polymorphes d'apalutamide
IT201900003839A1 (it)	2019-03-15	2020-09-15	Olon Spa	Sintesi di apalutamide amorfa stabile
WO2020234817A1 (fr) *	2019-05-21	2020-11-26	Laurus Labs Limited	Formes polymorphes d'apalutamide et leur préparation
IT201900010593A1 (it)	2019-07-01	2021-01-01	Dipharma Francis Srl	Forma cristallina di un inibitore di recettori degli androgeni
EP4017848A1 (fr) *	2019-08-22	2022-06-29	Dr. Reddy's Laboratories Ltd.	Procédé pour la préparation d'apalutamide
IT201900015974A1 (it)	2019-09-10	2021-03-10	Olon Spa	Apalutamide cristallina stabile in forma pura e processo per la sua preparazione
CN110590740A (zh) *	2019-09-20	2019-12-20	武汉大学	一种阿帕鲁胺化合物及其药物制剂
WO2022049265A1 (fr)	2020-09-04	2022-03-10	Synthon B.V.	Procédé amélioré pour la préparation d'apalutamide
CN112679468A (zh) *	2021-01-05	2021-04-20	四川科伦药物研究院有限公司	阿帕他胺的晶体形式、制备方法和用途
WO2023143090A1 (fr) *	2022-01-25	2023-08-03	成都苑东生物制药股份有限公司	Nouvelle forme cristalline de solvate d'apalutamide et son procédé de préparation
CN115536634B (zh) *	2022-10-17	2024-06-11	上海博悦生物科技有限公司	一种阿帕他胺的合成方法
CN116332907A (zh) *	2023-03-16	2023-06-27	奥锐特药业股份有限公司	一种无定形阿帕他胺的制备方法
WO2025153768A1 (fr) *	2024-01-18	2025-07-24	Nanoform Finland Oyj	Composition contenant de l'apalutamide nanométrique cristallin

Family Cites Families (9)

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US5323907A (en)	1992-06-23	1994-06-28	Multi-Comp, Inc.	Child resistant package assembly for dispensing pharmaceutical medications
US7709517B2 (en)	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
CN101032483B (zh) *	2006-03-09	2011-05-04	陈德桂	调节雄激素受体活性的乙内酰脲衍生物及其应用
PL3412290T3 (pl)	2006-03-27	2021-09-06	The Regents Of The University Of California	Modulator receptora androgenowego do leczenia raka gruczołu krokowego i chorób związanych z receptorem androgenowym
CA2648139A1 (fr) *	2006-03-29	2007-11-08	The Regents Of The University Of California	Composes de diarylthiohydantoine et leur utilisation dans le traitement de troubles d'hyperproliferation
WO2008119015A2 (fr) *	2007-03-27	2008-10-02	Sloan-Kettering Institute For Cancer Research	Synthèse de dérivés de la thiohydantoïne
EA028869B1 (ru)	2010-02-16	2018-01-31	Арагон Фармасьютикалс, Инк.	Модуляторы рецептора андрогенов и их применение
ES2809738T3 (es)	2012-06-07	2021-03-05	Aragon Pharmaceuticals Inc	Formas cristalinas de un modulador de receptor de andrógenos
WO2019242439A1 (fr)	2018-06-20	2019-12-26	苏州科睿思制药有限公司	Formes cristallines de l'arn-509, procédé de préparation correspondant et utilisation associée

2013
- 2013-06-04 ES ES18157435T patent/ES2809738T3/es active Active
- 2013-06-04 TW TW102119817A patent/TWI532732B/zh active
- 2013-06-04 CA CA3114726A patent/CA3114726A1/fr active Pending
- 2013-06-04 CA CA2875767A patent/CA2875767C/fr active Active
- 2013-06-04 ME MEP-2020-163A patent/ME03815B/fr unknown
- 2013-06-04 CN CN202110417935.XA patent/CN113135892A/zh active Pending
- 2013-06-04 US US14/406,520 patent/US9481663B2/en active Active
- 2013-06-04 RS RS20210739A patent/RS61988B1/sr unknown
- 2013-06-04 SM SM20180311T patent/SMT201800311T1/it unknown
- 2013-06-04 DK DK18157435.1T patent/DK3348553T3/da active
- 2013-06-04 SG SG10201610249TA patent/SG10201610249TA/en unknown
- 2013-06-04 SI SI201331894T patent/SI3533792T1/sl unknown
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- 2013-06-04 HR HRP20180902TT patent/HRP20180902T1/hr unknown
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- 2013-06-04 CN CN201610202980.2A patent/CN105693692A/zh active Pending
- 2013-06-04 PE PE2019002096A patent/PE20200725A1/es unknown
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- 2013-06-04 CN CN201380041652.3A patent/CN104619692A/zh active Pending
- 2013-06-04 EP EP18157435.1A patent/EP3348553B1/fr not_active Revoked
- 2013-06-04 HU HUE13800681A patent/HUE038082T2/hu unknown
- 2013-06-04 PL PL19169275T patent/PL3533792T3/pl unknown
- 2013-06-04 SG SG11201408140QA patent/SG11201408140QA/en unknown
- 2013-06-04 WO PCT/US2013/044116 patent/WO2013184681A1/fr not_active Ceased
- 2013-06-04 IL IL267608A patent/IL267608B2/en unknown
- 2013-06-04 PT PT138006812T patent/PT2858985T/pt unknown
- 2013-06-04 EP EP21171579.2A patent/EP3922629A1/fr active Pending
- 2013-06-04 LT LTEP18157435.1T patent/LT3348553T/lt unknown
- 2013-06-04 HK HK15111086.5A patent/HK1210175A1/xx unknown
- 2013-06-04 AU AU2013271751A patent/AU2013271751B2/en active Active
- 2013-06-04 ES ES13800681.2T patent/ES2670683T3/es active Active
- 2013-06-04 IN IN10084DEN2014 patent/IN2014DN10084A/en unknown
- 2013-06-04 MX MX2014015005A patent/MX356754B/es active IP Right Grant
- 2013-06-04 LT LTEP13800681.2T patent/LT2858985T/lt unknown
- 2013-06-04 ES ES19169275T patent/ES2875932T3/es active Active
- 2013-06-04 SM SM20200496T patent/SMT202000496T1/it unknown
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- 2013-06-04 EP EP19169275.5A patent/EP3533792B1/fr active Active
- 2013-06-04 SG SG10201610248SA patent/SG10201610248SA/en unknown
- 2013-06-04 HU HUE19169275A patent/HUE054595T2/hu unknown
- 2013-06-04 DK DK19169275.5T patent/DK3533792T3/da active
- 2013-06-04 PT PT181574351T patent/PT3348553T/pt unknown
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- 2013-06-04 EA EA201492272A patent/EA028791B1/ru unknown
- 2013-06-04 EA EA201992010A patent/EA201992010A1/ru unknown
- 2013-06-04 RS RS20200913A patent/RS60617B1/sr unknown
- 2013-06-04 JP JP2015516121A patent/JP6182209B2/ja active Active
- 2013-06-04 PE PE2014002383A patent/PE20150631A1/es active IP Right Grant
- 2013-06-04 PE PE2020000234A patent/PE20200795A1/es unknown
- 2013-06-04 UA UAA201500086A patent/UA115665C2/uk unknown
- 2013-06-04 KR KR1020157000266A patent/KR102062024B1/ko active Active
- 2013-06-04 PT PT191692755T patent/PT3533792T/pt unknown
- 2013-06-04 RS RS20180680A patent/RS57370B1/sr unknown
- 2013-06-04 HU HUE18157435A patent/HUE050357T2/hu unknown
- 2013-06-04 CA CA3008345A patent/CA3008345C/fr active Active
- 2013-06-04 TR TR2018/08939T patent/TR201808939T4/tr unknown
- 2013-06-04 SI SI201331010T patent/SI2858985T1/sl unknown
- 2013-06-04 KR KR1020197033592A patent/KR102195916B1/ko active Active
- 2013-06-04 NZ NZ702203A patent/NZ702203A/en unknown
- 2013-06-04 UA UAA201702779A patent/UA123142C2/uk unknown
- 2013-06-04 DK DK13800681.2T patent/DK2858985T3/en active
- 2013-06-04 EA EA201791592A patent/EA033956B1/ru unknown
- 2013-06-04 EP EP13800681.2A patent/EP2858985B1/fr active Active
- 2013-06-04 ME MEP-2018-158A patent/ME03081B/fr unknown
- 2013-06-04 CA CA3055660A patent/CA3055660A1/fr not_active Abandoned
- 2013-06-04 BR BR112014030678A patent/BR112014030678A2/pt not_active Application Discontinuation
- 2013-06-04 NZ NZ717683A patent/NZ717683A/en unknown
- 2013-06-04 MY MYPI2014703627A patent/MY187500A/en unknown
2014
- 2014-12-01 CR CR20140549A patent/CR20140549A/es unknown
- 2014-12-04 IL IL236055A patent/IL236055A0/en unknown
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- 2014-12-05 EC ECIEPI201430098A patent/ECSP14030098A/es unknown
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- 2014-12-05 GT GT201400283A patent/GT201400283A/es unknown
- 2014-12-09 CO CO14270612A patent/CO7240407A2/es unknown
2015
- 2015-01-06 ZA ZA2015/00076A patent/ZA201500076B/en unknown
2016
- 2016-07-26 PH PH12016501470A patent/PH12016501470B1/en unknown
- 2016-09-12 US US15/262,522 patent/US9994545B2/en active Active
- 2016-12-19 HK HK16114389.2A patent/HK1226066A1/zh unknown
2017
- 2017-01-17 AU AU2017200298A patent/AU2017200298B2/en active Active
- 2017-02-15 JP JP2017025746A patent/JP6345821B2/ja active Active
- 2017-12-22 AU AU2017279807A patent/AU2017279807B2/en active Active
2018
- 2018-05-09 US US15/975,449 patent/US10308630B2/en active Active
- 2018-05-23 JP JP2018098638A patent/JP2018141009A/ja active Pending
- 2018-05-31 IL IL259738A patent/IL259738B/en active IP Right Grant
- 2018-07-06 CY CY20181100712T patent/CY1120393T1/el unknown
2019
- 2019-04-15 US US16/384,002 patent/US10526310B2/en active Active
- 2019-07-10 US US16/507,780 patent/US10556882B2/en active Active
- 2019-12-11 US US16/710,785 patent/US10766875B2/en active Active
2020
- 2020-06-15 IL IL275413A patent/IL275413A/en unknown
- 2020-07-29 US US16/942,069 patent/US10934271B2/en active Active
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2021
- 2021-01-26 US US17/158,806 patent/US12018008B2/en active Active
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- 2021-11-02 NO NO2021046C patent/NO2021046I1/no unknown
- 2021-11-02 LU LU00236C patent/LUC00236I2/fr unknown
- 2021-11-03 FR FR21C1050C patent/FR21C1050I2/fr active Active
- 2021-11-03 LT LTPA2021525C patent/LTC3533792I2/lt unknown
- 2021-11-03 NL NL301144C patent/NL301144I2/nl unknown
- 2021-11-04 HU HUS2100047C patent/HUS2100047I1/hu unknown
- 2021-11-04 CY CY2021032C patent/CY2021032I2/el unknown
2024
- 2024-05-13 US US18/662,345 patent/US20250092011A1/en not_active Abandoned

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HUE054595T2 (hu)	2021-09-28
MY187500A (en)	2021-09-24
TW201402561A (zh)	2014-01-16
SI3348553T1 (sl)	2020-11-30
CA2875767A1 (fr)	2013-12-12
RS61988B1 (sr)	2021-07-30
EA201492272A1 (ru)	2015-05-29
US20190241539A1 (en)	2019-08-08
IL267608A (en)	2019-08-29
PE20200795A1 (es)	2020-08-10
HUE038082T2 (hu)	2018-09-28
US12018008B2 (en)	2024-06-25
RS60617B1 (sr)	2020-09-30
MX356754B (es)	2018-06-11
EP3533792A1 (fr)	2019-09-04
PE20200725A1 (es)	2020-07-21
KR102195916B1 (ko)	2020-12-30
MX2014015005A (es)	2015-09-04
KR20150021993A (ko)	2015-03-03
PL3348553T3 (pl)	2021-02-08
TWI532732B (zh)	2016-05-11
LUC00236I2 (fr)	2025-02-03
LT3533792T (lt)	2021-07-26
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AU2013271751B2 (en)	2017-02-23
CN104619692A (zh)	2015-05-13
EP3348553B1 (fr)	2020-07-08
SI2858985T1 (sl)	2018-12-31
ZA201500076B (en)	2016-10-26
CY1120393T1 (el)	2019-07-10
CR20140549A (es)	2015-04-06
IL259738A (en)	2018-07-31
HRP20201387T1 (hr)	2020-11-27
CA3055660A1 (fr)	2013-12-12
HK1210175A1 (en)	2016-04-15
US20210163441A1 (en)	2021-06-03
PL3533792T3 (pl)	2021-11-29
FR21C1050I2 (fr)	2024-05-24
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CN113135892A (zh)	2021-07-20
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AU2017279807A1 (en)	2018-01-25
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BR112014030678A2 (pt)	2017-06-27
CA3008345C (fr)	2019-10-22
IL267608B1 (en)	2025-06-01
CN105693692A (zh)	2016-06-22
EP3348553A1 (fr)	2018-07-18
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SMT202000496T1 (it)	2020-11-10
TR201808939T4 (tr)	2018-07-23
NL301144I2 (nl)	2025-03-20
CO7240407A2 (es)	2015-04-17
DK3533792T3 (da)	2021-06-28
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HUS2100047I1 (hu)	2021-11-29
US20200115361A1 (en)	2020-04-16
CY2021032I2 (el)	2022-03-24

Publication	Publication Date	Title
FR21C1050I2 (fr)	2024-05-24	Formes cristallines d'un modulateur de récepteur d'androgène
LTC2493858I2 (lt)	2022-03-25	Androgeno receptorių moduliuojantys junginiai
EP2906226A4 (fr)	2016-06-08	Modulation de l'expression de récepteur d'androgène
EP2742051A4 (fr)	2015-03-18	Forme amorphe de dolutegravir
EP2531029A4 (fr)	2013-05-29	Modulateurs sélectifs du récepteur des androgènes
DK2526425T3 (da)	2014-08-04	Fremgangsmåde til diagnosticering af endometriel receptivitet
EP2911666A4 (fr)	2016-10-12	Modulateurs du récepteur des androgènes androgéno-résistant
EP2635419A4 (fr)	2015-06-03	Modelage de nanostructures de forme non convexe
HUE036238T2 (hu)	2018-06-28	Szelektív androgén receptor modulátorokként ható indolkarbonitril vegyületek
EP2900664A4 (fr)	2016-03-09	Formes cristallines de dérivés de dihydropyrimidine
EP2688649A4 (fr)	2014-10-01	Formes polymorphes de lénalidomide