FR2197979A1 - Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acid - Google Patents
Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acidInfo
- Publication number
- FR2197979A1 FR2197979A1 FR7231655A FR7231655A FR2197979A1 FR 2197979 A1 FR2197979 A1 FR 2197979A1 FR 7231655 A FR7231655 A FR 7231655A FR 7231655 A FR7231655 A FR 7231655A FR 2197979 A1 FR2197979 A1 FR 2197979A1
- Authority
- FR
- France
- Prior art keywords
- aspartic acid
- amino
- fumaric acid
- acid
- prodn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title abstract 6
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 title abstract 4
- 239000001530 fumaric acid Substances 0.000 title abstract 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title abstract 3
- 102000003929 Transaminases Human genes 0.000 title abstract 2
- 108090000340 Transaminases Proteins 0.000 title abstract 2
- 241000589516 Pseudomonas Species 0.000 title 1
- 235000003704 aspartic acid Nutrition 0.000 title 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 title 1
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 abstract 3
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 abstract 3
- 229960005261 aspartic acid Drugs 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/20—Aspartic acid; Asparagine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A strain PO 7111 of the genus Pseudomonacea (I) is cultured aerobically in a nutrient medium contg molassis and a P- and N-source. The strain produces an amino-transferase in situ, able to convert fumaric acid to L-aspartic acid. After growth of (I) is optimum, culturing is ended and fumaric acid is added at 10%. Conversion takes place anaerobically at pref. pH of 9.0-9.5 and at pref. 57-60 degrees C. The L-aspartic acid formed is then isolated in known ways. The process produces L-aspartic acid in good yield and of high purity.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7231655A FR2197979A1 (en) | 1972-09-07 | 1972-09-07 | Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acid |
| GB4204773A GB1442439A (en) | 1972-09-07 | 1973-09-06 | Method of making l-aspartic acid from fumaric acid |
| JP48100390A JPS588837B2 (en) | 1972-09-07 | 1973-09-07 | Humarsankara L- Asparaginsano Tsukuruhouhou |
| NL7312344A NL184913C (en) | 1972-09-07 | 1973-09-07 | PROCESS FOR THE PREPARATION OF L-ASPARAGIC ACID AND L-ASPARAGINATE AMMONIA-LYASE IN SITU. |
| DE19732345271 DE2345271C2 (en) | 1972-09-07 | 1973-09-07 | Process for the production of L-aspartic acid from fumaric acid |
| DE19732366505 DE2366505C2 (en) | 1972-09-07 | 1973-09-07 | Use of the strain Pseudomonas ATCC 21973 for the in situ production of an aminotransferase |
| US05/418,863 US3933586A (en) | 1972-09-07 | 1973-11-26 | Method of making l-aspartic acid from fumaric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7231655A FR2197979A1 (en) | 1972-09-07 | 1972-09-07 | Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2197979A1 true FR2197979A1 (en) | 1974-03-29 |
| FR2197979B1 FR2197979B1 (en) | 1975-01-03 |
Family
ID=9103960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7231655A Granted FR2197979A1 (en) | 1972-09-07 | 1972-09-07 | Amino-transferase producing strain pseudomonas PO 7111 - for prodn of aspartic acid from fumaric acid |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2197979A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2514782A1 (en) * | 1981-10-15 | 1983-04-22 | Genex Corp | PROCESS FOR THE PREPARATION OF AQUEOUS SOLUTION, PRACTICALLY FREE OF CELLS, ASPARTASE AND ITS APPLICATION TO THE MANUFACTURE OF ASPARTIC ACID |
| US6344348B1 (en) | 1996-10-13 | 2002-02-05 | Amylum Belgium N.V. | Process for the production of aspartic acid condensate |
-
1972
- 1972-09-07 FR FR7231655A patent/FR2197979A1/en active Granted
Non-Patent Citations (1)
| Title |
|---|
| CHEMICAL ABSTRACTS VOLUME 70 NO 27644 1969 ) * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2514782A1 (en) * | 1981-10-15 | 1983-04-22 | Genex Corp | PROCESS FOR THE PREPARATION OF AQUEOUS SOLUTION, PRACTICALLY FREE OF CELLS, ASPARTASE AND ITS APPLICATION TO THE MANUFACTURE OF ASPARTIC ACID |
| US6344348B1 (en) | 1996-10-13 | 2002-02-05 | Amylum Belgium N.V. | Process for the production of aspartic acid condensate |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2197979B1 (en) | 1975-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CD | Change of name or company name |