FR2150594A1 - Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensive - Google Patents
Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensiveInfo
- Publication number
- FR2150594A1 FR2150594A1 FR7131188A FR7131188A FR2150594A1 FR 2150594 A1 FR2150594 A1 FR 2150594A1 FR 7131188 A FR7131188 A FR 7131188A FR 7131188 A FR7131188 A FR 7131188A FR 2150594 A1 FR2150594 A1 FR 2150594A1
- Authority
- FR
- France
- Prior art keywords
- alkanones
- spasmolytic
- bronchodilator
- ulcer
- diphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000000767 anti-ulcer Effects 0.000 title abstract 2
- 229940124630 bronchodilator Drugs 0.000 title abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title abstract 2
- 230000002048 spasmolytic effect Effects 0.000 title abstract 2
- 208000001953 Hypotension Diseases 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Cpds. are of formula: (where n is 3 or 4; A is the gp. where R', R2 are alkyl (C1-C3) or is pyrrolidino, piperidino or morpholino; or A is: where R3 is alkyl (C1-C3) and Hal is halogen). The cpds. have analgesic, anti-inflammatory, spasmolytic, anti-ulcer, bronchodilator and hypotensive activity, and may be prepd. by treating w-halo-1,2-diphenyl-1-alkanones with the appropriate sec. amines.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7131188A FR2150594A1 (en) | 1971-08-27 | 1971-08-27 | Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7131188A FR2150594A1 (en) | 1971-08-27 | 1971-08-27 | Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensive |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2150594A1 true FR2150594A1 (en) | 1973-04-13 |
| FR2150594B1 FR2150594B1 (en) | 1975-02-07 |
Family
ID=9082284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7131188A Granted FR2150594A1 (en) | 1971-08-27 | 1971-08-27 | Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensive |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2150594A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4277474A (en) * | 1978-02-22 | 1981-07-07 | Nippon Zoki Pharmaceutical Co., Ltd. | Treatment of allergic symptoms with propanone derivatives |
| EP0264400B1 (en) | 1986-05-02 | 1989-10-04 | Sanitized Ag | Synthesizing process |
-
1971
- 1971-08-27 FR FR7131188A patent/FR2150594A1/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4277474A (en) * | 1978-02-22 | 1981-07-07 | Nippon Zoki Pharmaceutical Co., Ltd. | Treatment of allergic symptoms with propanone derivatives |
| EP0264400B1 (en) | 1986-05-02 | 1989-10-04 | Sanitized Ag | Synthesizing process |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2150594B1 (en) | 1975-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |