FR2036045A5 - Arginine pantothenate prepn - Google Patents
Arginine pantothenate prepnInfo
- Publication number
- FR2036045A5 FR2036045A5 FR6905703A FR6905703A FR2036045A5 FR 2036045 A5 FR2036045 A5 FR 2036045A5 FR 6905703 A FR6905703 A FR 6905703A FR 6905703 A FR6905703 A FR 6905703A FR 2036045 A5 FR2036045 A5 FR 2036045A5
- Authority
- FR
- France
- Prior art keywords
- pantothenate
- arginine
- acid
- stage
- prepn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 title abstract 7
- 235000019161 pantothenic acid Nutrition 0.000 title abstract 5
- 239000011713 pantothenic acid Substances 0.000 title abstract 5
- 239000004475 Arginine Substances 0.000 title abstract 4
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title abstract 4
- 229940014662 pantothenate Drugs 0.000 title abstract 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 6
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- 235000006408 oxalic acid Nutrition 0.000 abstract 2
- 229940055726 pantothenic acid Drugs 0.000 abstract 2
- 235000011149 sulphuric acid Nutrition 0.000 abstract 2
- 239000001117 sulphuric acid Substances 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 abstract 1
- 229960002079 calcium pantothenate Drugs 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
In a first stage calcium pantothenate is converted to pantothenic acid by the action of dilute sulphuric acid and then is a second stage the pantothenic acid is contacted in the nascent state with arginine base at normal temp. to produce arginine pantothenate. Pref. the second stage takes place under moderate vacuum, Inthe first stage oxalic acid may be used instead of sulphuric acid, the absence of calcium and oxalic acid being verified at the end of the reaction. Arginine pantothenate provides in a single molecule an amino acid and a water-soluble vitamin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6905703A FR2036045A5 (en) | 1969-03-03 | 1969-03-03 | Arginine pantothenate prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6905703A FR2036045A5 (en) | 1969-03-03 | 1969-03-03 | Arginine pantothenate prepn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2036045A5 true FR2036045A5 (en) | 1970-12-24 |
Family
ID=9029943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6905703A Expired FR2036045A5 (en) | 1969-03-03 | 1969-03-03 | Arginine pantothenate prepn |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2036045A5 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2198738A1 (en) * | 1972-09-14 | 1974-04-05 | Tixier Georges | L-Arginine pantothenate prepn - from pure panotaenic acid and arginine, is dried by azeotropic distn |
| US3876801A (en) * | 1971-10-13 | 1975-04-08 | Georges Tixier | Medicine comprising lysine derivatives |
-
1969
- 1969-03-03 FR FR6905703A patent/FR2036045A5/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3876801A (en) * | 1971-10-13 | 1975-04-08 | Georges Tixier | Medicine comprising lysine derivatives |
| FR2198738A1 (en) * | 1972-09-14 | 1974-04-05 | Tixier Georges | L-Arginine pantothenate prepn - from pure panotaenic acid and arginine, is dried by azeotropic distn |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| ST | Notification of lapse |