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FR2099730A5 - - Google Patents

Info

Publication number
FR2099730A5
FR2099730A5 FR7028410A FR7028410A FR2099730A5 FR 2099730 A5 FR2099730 A5 FR 2099730A5 FR 7028410 A FR7028410 A FR 7028410A FR 7028410 A FR7028410 A FR 7028410A FR 2099730 A5 FR2099730 A5 FR 2099730A5
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7028410A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Application granted granted Critical
Publication of FR2099730A5 publication Critical patent/FR2099730A5/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7028410A 1970-07-15 1970-07-31 Expired FR2099730A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5524070A 1970-07-15 1970-07-15

Publications (1)

Publication Number Publication Date
FR2099730A5 true FR2099730A5 (fr) 1972-03-17

Family

ID=21996600

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7028410A Expired FR2099730A5 (fr) 1970-07-15 1970-07-31

Country Status (8)

Country Link
US (1) US3755322A (fr)
AT (2) AT299216B (fr)
AU (1) AU1826570A (fr)
BE (1) BE754242A (fr)
CA (1) CA982577A (fr)
FR (1) FR2099730A5 (fr)
GB (1) GB1339749A (fr)
NL (1) NL7011392A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0945447A1 (fr) * 1998-03-27 1999-09-29 Janssen Pharmaceutica N.V. Dérivés de 1,3,5-triazine trisubstituées pour le traitement de l'infection par le VIH
WO2000027828A3 (fr) * 1998-11-10 2000-09-21 Janssen Pharmaceutica Nv Derives de triazine 2,4-disubstitues
WO2006024175A1 (fr) * 2004-09-03 2006-03-09 Prometic Biosciences Inc. COMPOSÉS À BASE DE 2,4,6-TRIAMINO-S-TRIAZINE RELIÉS À LA PARTIE DE QUEUE (Fc) DES IMMUNOGLOBULINES ET LEUR UTILISATION
US7241458B1 (en) 1999-09-24 2007-07-10 Janssen Pharmaceutica N.V. Antiviral compositions

Families Citing this family (58)

* Cited by examiner, † Cited by third party
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US3928344A (en) * 1971-12-27 1975-12-23 Degussa Phenylenediamine-s-triazines
IT1060458B (it) * 1975-12-18 1982-08-20 Chimosa Chimica Organica Spa Composti piperidil triazinici adatti per la stabilizzazione di polimeri sintetici e procedimento per la loro preparazione
DE3006803A1 (de) * 1980-02-23 1981-09-03 Bayer Ag, 5090 Leverkusen Vulkanisationsbeschleuniger auf basis von melaminderivaten, melaminderivate enthaltende kautschukmassen sowie ein verfahren zur vulkanisation von kautschuken
DE3401675A1 (de) * 1984-01-19 1985-07-25 Bayer Ag, 5090 Leverkusen Neue polyamine und ein verfahren zu ihrer herstellung
DE3438694A1 (de) * 1984-10-23 1986-04-24 Basf Ag, 6700 Ludwigshafen Neue amidoalkylmelamine und aminoalkylmelamine und verfahren zu ihrer herstellung
US6225378B1 (en) * 1999-07-01 2001-05-01 Industrial Technology Research Institute Triazine hardener and epoxy composition containing the same
ATE346064T1 (de) * 2000-09-15 2006-12-15 Vertex Pharma Pyrazolverbindungen als protein-kinasehemmer
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) * 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
ATE354573T1 (de) 2000-12-21 2007-03-15 Vertex Pharma ßPYRAZOLVERBINDUNGEN, DIE SICH ALS PROTEINKINASEINHIBITOREN EIGNENß
SG159380A1 (en) * 2002-02-06 2010-03-30 Vertex Pharma Heteroaryl compounds useful as inhibitors of gsk-3
EP1485380B1 (fr) * 2002-03-15 2010-05-19 Vertex Pharmaceuticals Incorporated Azolylaminoazines inhibitrices des proteines kinases
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
CN1319968C (zh) 2002-08-02 2007-06-06 沃泰克斯药物股份有限公司 用作gsk－3的抑制剂的吡唑组合物
WO2004072029A2 (fr) * 2003-02-06 2004-08-26 Vertex Pharmaceuticals Incorporated Compositions utiles en tant qu'inhibiteurs de proteine kinases
WO2005056547A2 (fr) * 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines utiles comme inhibiteurs des proteines kinases
ITMI20050222A1 (it) * 2005-02-15 2006-08-16 Milano Politecnico Lipidi cationici per la trasfezione di acidi nucleici
CA2619517A1 (fr) * 2005-08-18 2007-02-22 Michael Mortimore Inhibiteurs de pyrazine kinases
JP5249770B2 (ja) * 2005-11-03 2013-07-31 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼインヒビターとして有用なアミノピリジン
EP2086965B1 (fr) * 2006-11-02 2010-02-10 Vertex Pharmaceuticals, Inc. Aminopyridines et aminopyrimidines utiles en tant qu'inhibiteurs de protéines kinases
DE602007007985D1 (de) * 2006-12-19 2010-09-02 Vertex Pharma Als inhibitoren von proteinkinasen geeignete aminopyrimidine
CA2679884A1 (fr) * 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines utiles en tant qu'inhibiteurs des proteines kinases
MX2009009592A (es) * 2007-03-09 2009-11-10 Vertex Pharma Aminopiridinas utiles como inhibidores de proteinas cinasas.
KR20090120510A (ko) * 2007-03-09 2009-11-24 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제 억제제로서 유용한 아미노피리미딘
CA2683785A1 (fr) 2007-04-13 2008-10-23 Vertex Pharmaceuticals Incorporated Aminopyrimidines utilisees en tant qu'inhibiteurs de kinases
AU2008247592A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
JP5389786B2 (ja) * 2007-05-02 2014-01-15 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼ阻害として有用なアミノピリミジン
MX2009011811A (es) * 2007-05-02 2010-01-14 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasa.
CN101687852A (zh) * 2007-05-24 2010-03-31 沃泰克斯药物股份有限公司 可用作激酶抑制剂的噻唑类和吡唑类化合物
AU2008282156B2 (en) * 2007-07-31 2014-07-17 Vertex Pharmaceuticals Incorporated Process for preparing 5-fluoro-1H-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof
CN102215816A (zh) * 2008-09-03 2011-10-12 沃泰克斯药物股份有限公司 共晶和包含所述共晶的药物制剂
CN108524505A (zh) 2009-03-13 2018-09-14 安吉奥斯医药品有限公司 用于细胞增殖相关病症的方法和组合物
PT2448582T (pt) 2009-06-29 2017-07-10 Agios Pharmaceuticals Inc Compostos e composições terapêuticas
EP3561077B1 (fr) 2009-10-21 2022-12-21 Les Laboratoires Servier Procédés pour des troubles liés à la prolifération cellulaire
CN108451955B (zh) 2011-05-03 2022-02-01 安吉奥斯医药品有限公司 用于治疗的丙酮酸激酶活化剂
CN102827170A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
CN102827073A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
IN2014MN00381A (fr) * 2011-08-04 2015-06-19 Colourtex Ind Ltd
KR101945073B1 (ko) * 2011-08-12 2019-02-01 우베 고산 가부시키가이샤 폴리이미드 전구체, 폴리이미드, 폴리이미드 필름, 및 이들의 제조에 사용되는 트리아진 화합물의 제조 방법
ES2675760T3 (es) 2012-01-06 2018-07-12 Agios Pharmaceuticals, Inc. Compuestos terapéuticamente activos y métodos de uso de los mismos
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
KR102049473B1 (ko) * 2012-05-14 2019-11-27 내셔널 유니버시티 코포레이션 이와테 유니버시티 폴리이미드 전구체, 폴리이미드, 폴리이미드 필름, 폴리이미드 금속 적층체 및 폴리이미드 용액
CN104822373B (zh) 2012-10-15 2018-08-28 安吉奥斯医药品有限公司 治疗性化合物和组合物
AU2014287121B2 (en) 2013-07-11 2018-11-15 Agios Pharmaceuticals, Inc. 2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer
CN105473560B (zh) * 2013-07-11 2020-01-17 安吉奥斯医药品有限公司 治疗活性化合物及其使用方法
US9579324B2 (en) 2013-07-11 2017-02-28 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
WO2015003360A2 (fr) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Composés thérapeutiquement actifs et leurs méthodes d'utilisation
KR102302091B1 (ko) 2013-07-11 2021-09-16 아지오스 파마슈티컬스 아이엔씨. 암 치료용의 ｉｄｈ２ 돌연변이체 억제제로서의 ｎ,６-비스(아릴 또는 헤테로아릴)-１，３，５-트리아진-２,４-디아민 화합물
WO2015003355A2 (fr) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Composés thérapeutiquement actifs et leurs méthodes d'utilisation
US20150031627A1 (en) 2013-07-25 2015-01-29 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
EA036325B1 (ru) 2014-03-14 2020-10-27 Аджиос Фармасьютикалз, Инк. Фармацевтическая композиция на основе твердой дисперсии ингибитора idh1
SMT202300344T1 (it) 2015-06-11 2023-11-13 Agios Pharmaceuticals Inc Metodi di utilizzo degli attivatori della piruvato chinasi
UA123401C2 (uk) 2015-10-15 2021-03-31 Аджиос Фармасьютікалз, Інк. Комбінована терапія для лікування злоякісних пухлин
ES2897959T3 (es) 2015-10-15 2022-03-03 Servier Lab Terapia de combinación para tratar neoplasias malignas
CN108640881A (zh) * 2018-04-26 2018-10-12 江汉大学 一种二胺单体及其合成方法
US10980788B2 (en) 2018-06-08 2021-04-20 Agios Pharmaceuticals, Inc. Therapy for treating malignancies
CN116790213B (zh) * 2023-07-04 2024-02-20 江苏特丽亮新材料科技有限公司 一种耐高温导电胶及其制备方法
CN118652248B (zh) * 2024-05-29 2025-02-14 南京理工大学 6-(4-氨基-1,2,5-噁二唑-3-基)-1,3,5-三嗪-2,4-二胺及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH441351A (de) * 1964-06-02 1967-08-15 Geigy Ag J R Verfahren zur Herstellung N2-substituierter 2,4,6-Triamino-1,3,5-triazine
DE1620178A1 (de) * 1965-12-03 1970-03-12 Ruhrchemie Ag Verfahren zur Herstellung von Aminoalkylamino-s-triazinen
US3637685A (en) * 1967-05-15 1972-01-25 Monacelli Walter J Triamino-s-triazines

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774235B2 (en) 1998-03-27 2004-08-10 Janssen Pharmaceutica N.V. Trisubstituted 1,3,5-triazine derivatives
KR100593396B1 (ko) * 1998-03-27 2006-06-28 얀센 파마슈티카 엔.브이. Ｈｉｖ 감염을 치료하기 위한 삼치환된 1,3,5-트리아진유도체
BG64903B1 (bg) * 1998-03-27 2006-08-31 Janssen Pharmaceutica N.V. Тризаместени 1, 3, 5-триазинови производни за лечение на hiv-инфекции
US6150360A (en) * 1998-03-27 2000-11-21 Janssen Pharmaceutica N.V. Trisubstituted 1,3,5-Triazine Derivatives
US6372729B1 (en) 1998-03-27 2002-04-16 Janssen Pharmaceutica N.V. Trisubstituted 1,3,5,-triazine derivatives
AP1475A (en) * 1998-03-27 2005-10-03 Janssen Pharmaceutica Nv Trisubstituted 1, 3, 5-triazine derivatives for treatment of HIV infections.
WO1999050256A1 (fr) * 1998-03-27 1999-10-07 Janssen Pharmaceutica N.V. Derives de 1,3,5-triazine trisubstitues pour le traitement d'infections a vih
EP0945447A1 (fr) * 1998-03-27 1999-09-29 Janssen Pharmaceutica N.V. Dérivés de 1,3,5-triazine trisubstituées pour le traitement de l'infection par le VIH
US7015221B2 (en) 1998-11-10 2006-03-21 Janssen Pharmaceutica, N.V. 2,4-disubstituted triazine derivatives
US6638932B1 (en) 1998-11-10 2003-10-28 Janssen Pharmaceutica N.V. 2,4-disubstituted triazine derivatives
AP1636A (en) * 1998-11-10 2006-07-17 Janssen Pharmaceutica Nv 2.4-disubstituted triazine derivatives.
WO2000027828A3 (fr) * 1998-11-10 2000-09-21 Janssen Pharmaceutica Nv Derives de triazine 2,4-disubstitues
US7241458B1 (en) 1999-09-24 2007-07-10 Janssen Pharmaceutica N.V. Antiviral compositions
US7887845B2 (en) 1999-09-24 2011-02-15 Janssen Pharmaceutica Nv Antiviral compositions
WO2006024175A1 (fr) * 2004-09-03 2006-03-09 Prometic Biosciences Inc. COMPOSÉS À BASE DE 2,4,6-TRIAMINO-S-TRIAZINE RELIÉS À LA PARTIE DE QUEUE (Fc) DES IMMUNOGLOBULINES ET LEUR UTILISATION

Also Published As

Publication number Publication date
NL7011392A (fr) 1972-01-18
CA982577A (en) 1976-01-27
AU1826570A (en) 1972-02-03
BE754242A (fr) 1971-02-01
AT299216B (de) 1972-06-12
US3755322A (en) 1973-08-28
AT299965B (de) 1972-07-10
GB1339749A (en) 1973-12-05

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