FR2068413A1 - 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives - Google Patents
1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensivesInfo
- Publication number
- FR2068413A1 FR2068413A1 FR6936151A FR6936151A FR2068413A1 FR 2068413 A1 FR2068413 A1 FR 2068413A1 FR 6936151 A FR6936151 A FR 6936151A FR 6936151 A FR6936151 A FR 6936151A FR 2068413 A1 FR2068413 A1 FR 2068413A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- hypo
- aryl
- hypertensives
- pyrazolines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000005555 hypertensive agent Substances 0.000 title abstract 2
- 230000001631 hypertensive effect Effects 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000004872 arterial blood pressure Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000036543 hypotension Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1-Alkyl-3-alkylamino-5-aryl-pyrazolines; hypo- and hypertensives. Cpds. of formula : (where R1, R2, R3, R4 and R5 are each H, halogen, alkyl, haloalkyl, or alkoxy; R6= alkyl of 1-6C; R7 and R8 are each alkyl of 1-8C, H, aryl or aralkyl, but are not both H) and their acid- addition salts, are useful as regulators of arterial blood-pressure for treating hyper- or hypo-tension.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6936151A FR2068413A1 (en) | 1969-10-22 | 1969-10-22 | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6936151A FR2068413A1 (en) | 1969-10-22 | 1969-10-22 | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2068413A1 true FR2068413A1 (en) | 1971-08-27 |
Family
ID=9041876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6936151A Withdrawn FR2068413A1 (en) | 1969-10-22 | 1969-10-22 | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2068413A1 (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3949083A (en) * | 1973-04-17 | 1976-04-06 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US3992404A (en) | 1973-04-17 | 1976-11-16 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4000294A (en) | 1973-04-17 | 1976-12-28 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4005215A (en) | 1973-04-17 | 1977-01-25 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4032646A (en) | 1973-04-17 | 1977-06-28 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4045571A (en) | 1973-04-17 | 1977-08-30 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4053621A (en) | 1974-06-06 | 1977-10-11 | Bayer Aktiengesellschaft | 1-[2-(βNaphthyloxy)ethyl]-3-methylpyrazolone-(5) and antithrombotic and antithrombolytic compositions and methods utilizing them |
| US4056533A (en) | 1973-04-17 | 1977-11-01 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4061653A (en) | 1972-06-23 | 1977-12-06 | Bayer Aktiengesellschaft | 1-Substituted-3-amino-pyrazol-5-ones |
| US4069334A (en) | 1973-12-20 | 1978-01-17 | Bayer Aktiengesellschaft | Pyrazole derivatives |
| US4081596A (en) | 1973-04-17 | 1978-03-28 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| USRE30420E (en) * | 1973-04-17 | 1980-10-21 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4288446A (en) * | 1973-04-17 | 1981-09-08 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US6387136B1 (en) | 1998-07-20 | 2002-05-14 | L'oreal S.A. | Compositions for dyeing keratin fibers, containing 3-aminopyrazoline derivatives as coupler, dyeing process and dyeing kit |
| WO2007093829A1 (en) * | 2006-02-17 | 2007-08-23 | Merck Sharp & Dohme Limited | 3-aminopyrazolines for treatment of neurodegenerative and psychiatric diseases |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2726248A (en) * | 1950-04-06 | 1955-12-06 | Ilfrod Ltd | 3-amino pyrazolines and process |
-
1969
- 1969-10-22 FR FR6936151A patent/FR2068413A1/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2726248A (en) * | 1950-04-06 | 1955-12-06 | Ilfrod Ltd | 3-amino pyrazolines and process |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4061653A (en) | 1972-06-23 | 1977-12-06 | Bayer Aktiengesellschaft | 1-Substituted-3-amino-pyrazol-5-ones |
| USRE30420E (en) * | 1973-04-17 | 1980-10-21 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US3992404A (en) | 1973-04-17 | 1976-11-16 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4000294A (en) | 1973-04-17 | 1976-12-28 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4005215A (en) | 1973-04-17 | 1977-01-25 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4032646A (en) | 1973-04-17 | 1977-06-28 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4045571A (en) | 1973-04-17 | 1977-08-30 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4288446A (en) * | 1973-04-17 | 1981-09-08 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4056533A (en) | 1973-04-17 | 1977-11-01 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US3949083A (en) * | 1973-04-17 | 1976-04-06 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4081596A (en) | 1973-04-17 | 1978-03-28 | Bayer Aktiengesellschaft | Pyrazol-5-ones |
| US4069334A (en) | 1973-12-20 | 1978-01-17 | Bayer Aktiengesellschaft | Pyrazole derivatives |
| US4053621A (en) | 1974-06-06 | 1977-10-11 | Bayer Aktiengesellschaft | 1-[2-(βNaphthyloxy)ethyl]-3-methylpyrazolone-(5) and antithrombotic and antithrombolytic compositions and methods utilizing them |
| US6387136B1 (en) | 1998-07-20 | 2002-05-14 | L'oreal S.A. | Compositions for dyeing keratin fibers, containing 3-aminopyrazoline derivatives as coupler, dyeing process and dyeing kit |
| WO2007093829A1 (en) * | 2006-02-17 | 2007-08-23 | Merck Sharp & Dohme Limited | 3-aminopyrazolines for treatment of neurodegenerative and psychiatric diseases |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2068413A1 (en) | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives | |
| SE7706520L (en) | GUANIDINDERIVAT | |
| SE7509130L (en) | SET FOR HEAT TREATMENT OF RAILS. | |
| SE443557B (en) | PROCEDURE FOR BACTERIAL OXIDATION OF IRON SALTS, AND USE OF THE RECOVERED SOLUTION | |
| CH441351A (en) | Process for the preparation of N2-substituted 2,4,6-triamino-1,3,5-triazines | |
| ES297241A1 (en) | Procedure for the preparation of pirazine derivatives (Machine-translation by Google Translate, not legally binding) | |
| FR2077455A1 (en) | 5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials | |
| FR2024548A1 (en) | Ortho-substd phenethylamines and medicaments | |
| FR2217328A1 (en) | Herbicidal anilides - N-alpha-haloacyl-N-(O-and/or S-contg heterocyclyl-(m)ethyl) -2-alkyl-aniline derivs | |
| ES410354A1 (en) | 1-(benzamido)pyridinium salts | |
| ES382583A1 (en) | Substituted indenylacetic acids and their derivatives | |
| NL7405629A (en) | PROCESS FOR PREPARING CYANURIC ACID. | |
| CH547294A (en) | PROCESS FOR THE PREPARATION OF BASIC SUBSTITUTED DERIVATIVES OF 1,2,3-BENZOTRIAZIN-4 (3H) -ONE. | |
| ES344030A1 (en) | Process for the preparation of nitrogen-containing derivatives of acids | |
| CH438341A (en) | Process for the preparation of derivatives of 2-mercapto-4,6-bis amino-s-triazine | |
| FR2027230A1 (en) | Imidazolidin-2-ones herbicides | |
| NL7514449A (en) | PROCESS FOR PREPARING BASIC SUBSTITUTED BENZENE-1,3-DISULPHONAMIDES. | |
| FR2081555A1 (en) | N-aryl-n-naphthyl methyl benzamidines - analgesics hypotensives and diuretics | |
| GB1097057A (en) | Imidazolinonesulphonamide derivatives | |
| NL7209299A (en) | Delta-4-3-oxo-11-beta-halo steroids - with hormonal activity | |
| FR2206320A1 (en) | 4-Hydroxy, amino or mercapto-5-oxy-pyrazolo (3,4-d)-pyrimidines - xanth-ine oxydase inhibitors useful as anti-gout and uricosuric agents | |
| ES390037A1 (en) | A PROCEDURE FOR THE PREPARATION OF NEW INDAMINAS OR SALTS OF INDAMINAS. | |
| CH551988A (en) | PROCESS FOR THE PREPARATION OF BASIC SUBSTITUTED DERIVATIVES OF 1,2,3-BENZOTRIAZIN-4 (3H) -ONE. | |
| ES311499A3 (en) | Procedure for the preparation of urea derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES450882A2 (en) | Procedure for preparation of new tetrahydropirimidinic compounds. (Machine-translation by Google Translate, not legally binding) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| ST | Notification of lapse |