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FR10C0012I2 - - Google Patents

Info

Publication number
FR10C0012I2
FR10C0012I2 FR10C0012C FR10C0012C FR10C0012I2 FR 10C0012 I2 FR10C0012 I2 FR 10C0012I2 FR 10C0012 C FR10C0012 C FR 10C0012C FR 10C0012 C FR10C0012 C FR 10C0012C FR 10C0012 I2 FR10C0012 I2 FR 10C0012I2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR10C0012C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9449457&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR10C0012(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of FR10C0012I1 publication Critical patent/FR10C0012I1/fr
Application granted granted Critical
Publication of FR10C0012I2 publication Critical patent/FR10C0012I2/fr
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR10C0012C 1993-07-21 2010-03-04 Active FR10C0012I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9308948A FR2707988B1 (en) 1993-07-21 1993-07-21 New antimitotic derivatives of binary alkaloids of catharantus rosesus, process for their preparation and pharmaceutical compositions comprising them.
PCT/FR1994/000898 WO1995003312A1 (en) 1993-07-21 1994-07-19 Novel antimitotic binary alkaloid derivatives extracted from catharanthus roseus

Publications (2)

Publication Number Publication Date
FR10C0012I1 FR10C0012I1 (en) 2010-04-16
FR10C0012I2 true FR10C0012I2 (en) 2011-04-01

Family

ID=9449457

Family Applications (2)

Application Number Title Priority Date Filing Date
FR9308948A Expired - Lifetime FR2707988B1 (en) 1993-07-21 1993-07-21 New antimitotic derivatives of binary alkaloids of catharantus rosesus, process for their preparation and pharmaceutical compositions comprising them.
FR10C0012C Active FR10C0012I2 (en) 1993-07-21 2010-03-04

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR9308948A Expired - Lifetime FR2707988B1 (en) 1993-07-21 1993-07-21 New antimitotic derivatives of binary alkaloids of catharantus rosesus, process for their preparation and pharmaceutical compositions comprising them.

Country Status (15)

Country Link
US (1) US5620985A (en)
EP (1) EP0710240B1 (en)
JP (1) JP3606872B2 (en)
AT (1) ATE146477T1 (en)
AU (1) AU693460B2 (en)
BR (1) BR1100311A (en)
CA (1) CA2167694C (en)
DE (2) DE69401216T2 (en)
DK (1) DK0710240T3 (en)
ES (1) ES2097659T3 (en)
FR (2) FR2707988B1 (en)
GR (1) GR3022659T3 (en)
LU (1) LU91660I2 (en)
NZ (2) NZ269172A (en)
WO (1) WO1995003312A1 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2737208A1 (en) * 1995-07-28 1997-01-31 Pf Medicament Fluorinated vindoline derivs - and their reaction products with catharanthine having anti-cancer properties
FR2761990B1 (en) * 1997-04-10 1999-06-25 Pf Medicament ANTIMITOTIC HALOGEN DERIVATIVES OF VINCA ALKALOIDS
FR2783522A1 (en) * 1998-09-21 2000-03-24 Pf Medicament New Vinca alkaloid derivatives useful as antitumor agents for treating cancer
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
US6890558B2 (en) * 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
WO2005055939A2 (en) 2003-12-04 2005-06-23 Amr Technology, Inc. Vinca derivatives
US7235564B2 (en) 2003-12-04 2007-06-26 Amr Technology, Inc. Vinorelbine derivatives
FR2863891B1 (en) * 2003-12-23 2006-03-24 Pf Medicament PHARMACEUTICAL COMPOSITION OF VINFLUNIN FOR PARENTAL ADMINISTRATION, PROCESS FOR PREPARATION AND USE
US20110015221A1 (en) * 2003-12-23 2011-01-20 Pierre Fabre Medicament Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same
EP1732947B1 (en) * 2004-03-05 2011-04-27 Vegenics Pty Ltd Growth factor binding constructs materials and methods
FR2894966B1 (en) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa NEW CRYSTALLINE FORM OF VINFLUNINE
EP1989212B1 (en) 2006-02-17 2013-06-19 Cascade Prodrug Inc. Treatment of hyperproliferative diseases with vinca alkaloid n-oxide and analogs
CN101108859A (en) * 2006-07-17 2008-01-23 上海恒瑞医药有限公司 Vinblastine compound, method of preparing the same and use in medicament thereof
WO2008033935A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinorelbine derivatives
WO2008033930A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinca derivatives
FR2905949B1 (en) 2006-09-20 2008-11-21 Pierre Fabre Medicament Sa FLUORINE DERIVATIVES OF CATHARANTHIN, PREPARATION THEREOF AND THEIR USE AS PRECURSORS OF ALKALOIDS DIMERES DE VINCA
CN101235046B (en) * 2007-01-29 2010-09-08 中国科学院上海药物研究所 Vinblastine derivative, its preparation method and use, and pharmaceutical composition containing the derivative
FR2912406B1 (en) * 2007-02-13 2009-05-08 Pierre Fabre Medicament Sa VINFLUNIN ANHYDROUS CRYSTAL SALTS, PROCESS FOR THEIR PREPARATION AND USE AS MEDICAMENT AND MEANS FOR PURIFYING VINFLUNIN.
EP1997534A1 (en) * 2007-05-31 2008-12-03 Pierre Fabre Medicament Cancer treatment combination therapy comprising vinflunine and trastuzumab
FR2918567B1 (en) * 2007-07-11 2012-08-03 Pf Medicament STABLE PHARMACEUTICAL COMPOSITION OF A WATER SOLUBLE SALT OF VINORELBINE.
FR2918566B1 (en) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa STABLE PHARMACEUTICAL COMPOSITION OF A WATER SOLUBLE SALT OF VINFLUNINE.
US20090076055A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched vinflunine
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
US8716263B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Synthesis of purine nucleosides
US8551973B2 (en) 2008-12-23 2013-10-08 Gilead Pharmasset Llc Nucleoside analogs
PA8855601A1 (en) 2008-12-23 2010-07-27 NUCLEOSID FORFORMIDATES
ES2575160T3 (en) 2010-03-15 2016-06-24 The Board Of Trustees Of The University Of Illinois Inhibitors of the interactions that bind the alpha subunit of beta integrin-protein G
WO2011123668A2 (en) 2010-03-31 2011-10-06 Pharmasset, Inc. Stereoselective synthesis of phosphorus containing actives
WO2012087943A2 (en) 2010-12-20 2012-06-28 The Regents Of The University Of Michigan Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
CN103788117A (en) * 2012-10-30 2014-05-14 何小解 Technology for continuously synthesizing Dehydrate Catharanthine, vinorelbine and Vinflunine
HU230462B1 (en) 2013-05-30 2016-07-28 Richter Gedeon Nyrt. A new bis-indole alkaloids as anticancer drugs
AU2015205995A1 (en) 2014-01-15 2016-07-28 Centre National De La Recherche Scientifique (Cnrs) Water soluble 4-azapodophyllotoxin analogs
EP3250611B1 (en) 2015-01-26 2021-04-21 The University of Chicago Car t-cells recognizing cancer-specific il 13r-alpha2
CN107683289B (en) 2015-01-26 2021-08-06 芝加哥大学 IL13Rα2 binding agents and their use in cancer therapy
CN108779129A (en) * 2016-03-09 2018-11-09 赛比亚斯药业股份公司 Vinorelbine list tartrate and its medicinal usage
EP3481422A1 (en) 2016-07-06 2019-05-15 Pierre Fabre Medicament Vinflunine and pd1 and/or pdl1 inhibitor as pharmaceutical combination
MA49849A (en) 2017-08-07 2020-06-17 Amgen Inc TREATMENT OF NEGATIVE TRIPLE BREAST CANCER OR COLORECTAL CANCER CONTAINING HEPATIC METASTASIS WITH ANTI-PD-L1 ANTIBODY AND ONCOLYTIC VIRUS
EP3941944A4 (en) 2019-03-20 2022-11-30 The Regents of the University of California BISPECIFIC CLAUDIN-6 ANTIBODIES
BR112021018608A2 (en) 2019-03-20 2021-11-23 Univ California Antibodies to claudin-6 and drug conjugates
WO2020222668A1 (en) 2019-04-30 2020-11-05 Instituto de Medicina Molecular João Lobo Antunes Rank pathway inhibitors in combination with cdk inhibitors
JP7763666B2 (en) 2019-06-24 2025-11-04 アムジェン インコーポレイテッド Inhibition of SIRPγ for cancer treatment
FR3140369B1 (en) 2022-10-04 2025-07-25 Univ Poitiers Process for the fluorination and/or cyclization of an alkene or amino alkyne in continuous flow and installation for implementing the process

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (en) * 1974-12-30 1978-07-21 Anvar
US4110330A (en) * 1977-05-27 1978-08-29 Eli Lilly And Company 5'-Acetonylvincristine and related compounds
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4307100A (en) * 1978-08-24 1981-12-22 Agence Nationale De Valorisation De La Recherche (Anvar) Nor bis-indole compounds usable as medicaments
US4320058A (en) * 1980-12-29 1982-03-16 Eli Lilly And Company 20'-Hydroxyvinblastine and related compounds
HU193772B (en) * 1985-06-12 1987-11-30 Richter Gedeon Vegyeszet Process for producing new nitro-bis-indole derivatives

Also Published As

Publication number Publication date
JPH09500634A (en) 1997-01-21
LU91660I2 (en) 2010-05-10
NZ328612A (en) 2000-05-26
EP0710240A1 (en) 1996-05-08
US5620985A (en) 1997-04-15
AU7266694A (en) 1995-02-20
WO1995003312A1 (en) 1995-02-02
ES2097659T3 (en) 1997-04-01
DE122010000012I1 (en) 2010-07-08
DK0710240T3 (en) 1997-06-02
NZ269172A (en) 1997-10-24
FR2707988A1 (en) 1995-01-27
GR3022659T3 (en) 1997-05-31
JP3606872B2 (en) 2005-01-05
AU693460B2 (en) 1998-07-02
FR2707988B1 (en) 1995-10-13
ATE146477T1 (en) 1997-01-15
DE69401216T2 (en) 1997-07-03
BR1100311A (en) 1999-08-31
FR10C0012I1 (en) 2010-04-16
DE69401216D1 (en) 1997-01-30
CA2167694C (en) 2007-03-06
CA2167694A1 (en) 1995-02-02
EP0710240B1 (en) 1996-12-18

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