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FR06C0014I2 - - Google Patents

Info

Publication number
FR06C0014I2
FR06C0014I2 FR06C0014C FR06C0014C FR06C0014I2 FR 06C0014 I2 FR06C0014 I2 FR 06C0014I2 FR 06C0014 C FR06C0014 C FR 06C0014C FR 06C0014 C FR06C0014 C FR 06C0014C FR 06C0014 I2 FR06C0014 I2 FR 06C0014I2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR06C0014C
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Publication of FR06C0014I1 publication Critical patent/FR06C0014I1/fr
Application granted granted Critical
Publication of FR06C0014I2 publication Critical patent/FR06C0014I2/fr
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR06C0014C 1995-03-27 2006-04-04 Active FR06C0014I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9503549 1995-03-27
PCT/FR1996/000448 WO1996030010A2 (fr) 1995-03-27 1996-03-26 Utilisation du fumagillol et ses derives pour preparer les medicaments destines a combattre les infections intestinales

Publications (2)

Publication Number Publication Date
FR06C0014I1 FR06C0014I1 (fr) 2006-11-17
FR06C0014I2 true FR06C0014I2 (fr) 2006-12-29

Family

ID=9477436

Family Applications (1)

Application Number Title Priority Date Filing Date
FR06C0014C Active FR06C0014I2 (fr) 1995-03-27 2006-04-04

Country Status (25)

Country Link
US (1) US5900431A (fr)
EP (1) EP0817626B1 (fr)
JP (1) JP3260378B2 (fr)
KR (1) KR100286920B1 (fr)
CN (1) CN1072485C (fr)
AP (1) AP646A (fr)
AT (1) ATE172641T1 (fr)
AU (1) AU706161B2 (fr)
CA (1) CA2216623C (fr)
CZ (1) CZ286821B6 (fr)
DE (1) DE69600879T2 (fr)
DK (1) DK0817626T3 (fr)
EA (1) EA000150B1 (fr)
ES (1) ES2128846T3 (fr)
FR (1) FR06C0014I2 (fr)
HU (1) HU224028B1 (fr)
IS (1) IS2048B (fr)
NO (1) NO315968B1 (fr)
NZ (1) NZ304906A (fr)
OA (1) OA10515A (fr)
PL (1) PL183378B1 (fr)
SK (1) SK283883B6 (fr)
TR (1) TR199701048T1 (fr)
UA (1) UA41446C2 (fr)
WO (1) WO1996030010A2 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3260378B2 (ja) * 1995-03-27 2002-02-25 サノフィーサンテラボ 腸感染に対する薬物の調製のためのフマギロールおよびその誘導体の使用
EP0799616A1 (fr) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Composition orale contenant un dérivé de fumagillol
AU2811400A (en) 1999-02-26 2000-09-14 Sanofi-Synthelabo Stable formulation containing fumagillin
JP3265394B1 (ja) * 2001-03-14 2002-03-11 泰三 矢野 アクリル系樹脂手袋
DE10341887A1 (de) * 2003-09-09 2005-03-31 Leopold Kostal Gmbh & Co. Kg Elektrisches Schaltermodul
FR2886855B1 (fr) * 2005-06-08 2009-07-17 Agronomique Inst Nat Rech Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocyliques
JP5557746B2 (ja) * 2007-11-28 2014-07-23 メルサナ セラピューティックス，インク． 生体適合性生分解性フマギリンアナログ複合体
NZ590732A (en) * 2008-07-18 2012-09-28 Zafgen Inc Methods of treating an overweight or obese subject using fumagillin
US8642650B2 (en) 2008-12-04 2014-02-04 Zafgen, Inc. Methods of treating an overweight or obese subject
WO2010065877A2 (fr) 2008-12-04 2010-06-10 Zafgen Corporation Procédés de traitement d'un sujet en surpoids ou obèse
WO2011044506A2 (fr) 2009-10-09 2011-04-14 Zafgen Corporation Composés sulfonés et leurs procédés de fabrication et d'utilisation
US8815309B2 (en) 2010-01-08 2014-08-26 Zafgen, Inc. Methods of treating a subject with benign prostate hyperplasia
WO2011085201A1 (fr) 2010-01-08 2011-07-14 Zafgen Corporation Composés de type fumagillol, et procédés correspondants de fabrication et d'utilisation
US20130266578A1 (en) 2010-04-07 2013-10-10 Thomas E. Hughes Methods of treating an overweight subject
KR20130043207A (ko) 2010-07-22 2013-04-29 자프겐 인크. 트리시클릭 화합물 및 이의 제조 및 사용 방법
PH12013500934A1 (en) 2010-11-09 2022-10-24 Zafgen Inc Crystalline solids of a metap-2 inhibitor and methods of making and using same
JP2013543899A (ja) 2010-11-29 2013-12-09 ザフゲン，インコーポレイテッド ６−ｏ−（４−ジメチルアミノエトキシ）シンナモイルフマギロールの非連日投与を用いた肥満の治療
BR112013018771A2 (pt) 2011-01-26 2019-09-17 Zafgen Inc compostos de tetrazol e métodos para fazer e usar os mesmos
BR112013023056A2 (pt) 2011-03-08 2018-10-09 Zafgen Inc derivados de oxaespiro [2,5] octano e análogos
WO2012154679A1 (fr) 2011-05-06 2012-11-15 Zafgen Corporation Composés de sulfonamide pyrazole tricycliques et leurs procédés de fabrication et d'utilisation
EP2705036B1 (fr) 2011-05-06 2015-08-12 Zafgen Inc. Composés de sulfonamide tricycliques et leurs procédés de fabrication et d'utilisation
AU2012253757B2 (en) 2011-05-06 2017-04-13 Zafgen Inc. Partially saturated tricyclic compounds and methods of making and using same
EP2763671A2 (fr) 2011-10-03 2014-08-13 Zafgen, Inc. Méthodes de traitement de troubles liés à l âge
KR20140112565A (ko) 2012-01-18 2014-09-23 자프겐 인크. 삼환식 설폰아마이드 화합물 그리고 그의 제조방법 및 그를 이용하는 방법
MX2014008705A (es) 2012-01-18 2015-02-05 Zafgen Inc Compuestos tricíclicos de sulfona y métodos para elaborarlos y utilizarlos.
AU2013259760A1 (en) 2012-05-07 2014-11-20 Zafgen, Inc. Polymorphic salt of the oxalate salt of 6-O-(4-dimethylaminoethoxy) cinnamoyl fumagillol and methods of making and using same
MX2014013599A (es) 2012-05-08 2015-05-11 Zafgen Inc Tratamiento de la obesidad hipotalamica con inhibidores de metap2.
KR20150016534A (ko) 2012-05-09 2015-02-12 자프겐 인크. 푸마지롤형 화합물 및 이의 제조 및 사용 방법
JP2015536981A (ja) 2012-11-05 2015-12-24 ザフゲン，インコーポレイテッド 三環式化合物ならびにその製造および使用方法
BR112015010196A2 (pt) 2012-11-05 2017-07-11 Zafgen Inc métodos de tratar doença do fígado
BR112015010223A2 (pt) 2012-11-05 2017-07-11 Zafgen Inc compostos tricíclicos para o uso no tratamento e/ou controle de obesidade
MX362391B (es) 2013-03-14 2019-01-15 Zafgen Inc Métodos de tratamiento de enfermedad renal y otros trastornos.
AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso
CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
CN106591389B (zh) * 2015-10-15 2019-10-11 中国科学院微生物研究所 一种利用烟曲霉菌生产烟曲霉素的方法
CN105622593B (zh) * 2016-02-25 2018-06-26 中国农业科学院蜜蜂研究所 一种烟曲霉素的提取方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2791530A (en) * 1953-08-31 1957-05-07 Abbott Lab Stabilized fumagillin compositions
JPH0629278B2 (ja) * 1985-06-26 1994-04-20 藤沢薬品工業株式会社 オキサスピロオクタン化合物
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
WO1992002240A2 (fr) * 1990-07-27 1992-02-20 Repligen Corporation Compositions et procedes nouveaux pour le traitement des maladies angiogeniques
US5328930A (en) * 1993-03-01 1994-07-12 Emory University Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin
JP3260378B2 (ja) * 1995-03-27 2002-02-25 サノフィーサンテラボ 腸感染に対する薬物の調製のためのフマギロールおよびその誘導体の使用
EP0799616A1 (fr) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Composition orale contenant un dérivé de fumagillol
CA2210600A1 (fr) * 1996-07-17 1998-01-17 Takashi Houkan Inhibiteur des metastases tumorales ou de la recurrence
AU3968597A (en) * 1996-08-02 1998-02-25 Children's Medical Center Corporation Method of regulating the female reproductive system through angiogenesis inhibitors

Also Published As

Publication number Publication date
ATE172641T1 (de) 1998-11-15
US5900431A (en) 1999-05-04
AP9701092A0 (en) 1997-10-31
KR19980703271A (ko) 1998-10-15
CZ286821B6 (en) 2000-07-12
ES2128846T3 (es) 1999-05-16
NZ304906A (en) 1999-06-29
SK130797A3 (en) 1998-03-04
WO1996030010A2 (fr) 1996-10-03
EP0817626B1 (fr) 1998-10-28
PL322470A1 (en) 1998-02-02
NO974466L (no) 1997-09-26
WO1996030010A3 (fr) 1996-11-28
SK283883B6 (sk) 2004-04-06
FR06C0014I1 (fr) 2006-11-17
KR100286920B1 (ko) 2001-04-16
JPH11506421A (ja) 1999-06-08
NO974466D0 (no) 1997-09-26
EP0817626A2 (fr) 1998-01-14
HUP9801220A3 (en) 2001-10-29
CN1072485C (zh) 2001-10-10
AU5278696A (en) 1996-10-16
UA41446C2 (uk) 2001-09-17
AP646A (en) 1998-04-27
IS4557A (is) 1997-09-11
EA000150B1 (ru) 1998-10-29
CZ304997A3 (en) 1997-12-17
DE69600879T2 (de) 1999-06-02
EA199700267A1 (ru) 1998-04-30
HU224028B1 (hu) 2005-05-30
CA2216623C (fr) 2005-05-31
TR199701048T1 (xx) 1998-01-21
JP3260378B2 (ja) 2002-02-25
CA2216623A1 (fr) 1996-10-03
IS2048B (is) 2005-09-15
CN1179715A (zh) 1998-04-22
OA10515A (fr) 2002-04-24
DK0817626T3 (da) 1999-07-12
PL183378B1 (pl) 2002-06-28
MX9707150A (es) 1998-07-31
NO315968B1 (no) 2003-11-24
DE69600879D1 (de) 1998-12-03
AU706161B2 (en) 1999-06-10
HUP9801220A2 (hu) 1999-09-28

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