FI971995L - Makrosykliset laktoniyhdisteet ja niiden tuotantomenetelmä - Google Patents
Makrosykliset laktoniyhdisteet ja niiden tuotantomenetelmä Download PDFInfo
- Publication number
- FI971995L FI971995L FI971995A FI971995A FI971995L FI 971995 L FI971995 L FI 971995L FI 971995 A FI971995 A FI 971995A FI 971995 A FI971995 A FI 971995A FI 971995 L FI971995 L FI 971995L
- Authority
- FI
- Finland
- Prior art keywords
- production method
- macrocyclic lactone
- lactone compounds
- compounds
- macrocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Polyesters Or Polycarbonates (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9401896 | 1994-11-10 | ||
| PCT/IB1995/000870 WO1996015131A1 (en) | 1994-11-10 | 1995-10-13 | Macrocyclic lactone compounds and their production process |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI971995A7 FI971995A7 (fi) | 1997-05-09 |
| FI971995L true FI971995L (fi) | 1997-05-09 |
| FI971995A0 FI971995A0 (fi) | 1997-05-09 |
Family
ID=1341416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI971995A FI971995A0 (fi) | 1994-11-10 | 1995-10-13 | Makrosykliset laktoniyhdisteet ja niiden tuotantomenetelmä |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6001998A (fi) |
| EP (1) | EP0854874B1 (fi) |
| JP (1) | JP3061863B2 (fi) |
| AT (1) | ATE239024T1 (fi) |
| CA (1) | CA2204739C (fi) |
| DE (1) | DE69530616T2 (fi) |
| DK (1) | DK0854874T3 (fi) |
| ES (1) | ES2194054T3 (fi) |
| FI (1) | FI971995A0 (fi) |
| MX (1) | MX9703484A (fi) |
| PT (1) | PT854874E (fi) |
| WO (1) | WO1996015131A1 (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0854874B1 (en) * | 1994-11-10 | 2003-05-02 | Pfizer Inc. | Macrocyclic lactone compounds and their production process |
| ATE411019T1 (de) * | 2001-05-02 | 2008-10-15 | Brni Neurosciences Inst | Kohlensäureanhydrase-aktivatoren zur verbesserung der lern- und gedächtnisleistung |
| US6551591B1 (en) | 2001-09-07 | 2003-04-22 | Essential Therapeutics, Inc. | Antibiotics from microbispora |
| US20050065205A1 (en) * | 2002-03-07 | 2005-03-24 | Daniel Alkon | Methods for Alzheimer's disease treatment and cognitive enhance |
| US6825229B2 (en) | 2002-03-07 | 2004-11-30 | Blanchette Rockefeller Neurosciences Institute | Methods for Alzheimer's Disease treatment and cognitive enhancement |
| US20080004332A1 (en) * | 2002-03-07 | 2008-01-03 | Alkon Daniel L | Methods for alzheimer's disease treatment and cognitive enhancement |
| CN1946656B (zh) * | 2004-02-17 | 2011-08-24 | 托马斯·E·约翰逊 | 形成大环化合物的方法、组合物和设备 |
| TW201206425A (en) * | 2004-05-18 | 2012-02-16 | Brni Neurosciences Inst | Treatment of depressive disorders |
| CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| CA2598805A1 (en) * | 2005-02-24 | 2006-08-31 | Biocern, Inc. | Sperm cell separation methods and compositions |
| WO2006119211A2 (en) * | 2005-05-02 | 2006-11-09 | Genaera Corporation | Methods and compositions for treating ocular disorders |
| EP1915145A1 (en) | 2005-07-29 | 2008-04-30 | Blanchette Rockefeller Neurosciences Institute | Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory |
| EP2762136A1 (en) | 2006-07-28 | 2014-08-06 | Blanchette Rockefeller Neurosciences, Institute | Methods of stimulating cellular growth, synaptic remodeling and consolidation of long-term memory |
| RU2475539C2 (ru) * | 2006-08-30 | 2013-02-20 | Байосерн, Инк. | Способы разделения сперматозоидов и применяемые для этого композиции, содержащие аптамеры или последовательности нуклеиновых кислот |
| US10695327B2 (en) | 2006-09-13 | 2020-06-30 | Elixir Medical Corporation | Macrocyclic lactone compounds and methods for their use |
| JP6049160B2 (ja) | 2006-09-13 | 2016-12-27 | エリクシアー メディカル コーポレイション | 大環状ラクトン化合物およびその使用方法 |
| US8088789B2 (en) | 2006-09-13 | 2012-01-03 | Elixir Medical Corporation | Macrocyclic lactone compounds and methods for their use |
| CA3006091A1 (en) | 2007-02-09 | 2008-08-21 | Blanchette Rockefeller Neurosciences Institute | Therapeutic effects of bryostatins, bryologs, and other related substances on ischemia/stroke-induced memory impairment and brain injury |
| EP3332797A3 (en) | 2007-02-09 | 2018-08-01 | Blanchette Rockefeller Neurosciences Institute | Therapeutic effects of bryostatins, bryologs and other related substances on head trauma-induced memory impairment and brain injury |
| CN102421441B (zh) * | 2009-05-01 | 2015-04-01 | 糖模拟物有限公司 | E-选择蛋白和cxcr4趋化因子受体的异双功能抑制剂 |
| EP2473161B1 (en) * | 2009-08-31 | 2017-05-17 | Dr. Reddy's Laboratories Ltd. | Topical formulations comprising a steroid |
| CA2804789A1 (en) | 2010-07-08 | 2012-01-12 | Daniel L. Alkon | Pkc activators and anticoagulant in regimen for treating stroke |
| US9597312B2 (en) | 2010-08-19 | 2017-03-21 | Cognitive Research Enterprises, Inc. | Treatment of cognitive disorders associated with abnormal dendritic spines using PKC activators |
| EP2776018B1 (en) | 2011-11-13 | 2021-08-25 | Cognitive Research Enterprises, Inc. | Pkc activators and combinations thereof |
| WO2016183252A1 (en) | 2015-05-11 | 2016-11-17 | Alkon, Daniel, L. | Treatment of neurodegenerative conditions using pkc activators after determining the presence of the apoe4 allele |
| CN107827803A (zh) * | 2017-11-28 | 2018-03-23 | 绍兴厚普生物科技有限责任公司 | 一种从发酵液中提取l‑羟脯氨酸的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6903238A (fi) * | 1968-03-04 | 1969-09-08 | ||
| US5091389A (en) * | 1991-04-23 | 1992-02-25 | Merck & Co., Inc. | Lipophilic macrolide useful as an immunosuppressant |
| US5674732A (en) * | 1992-04-27 | 1997-10-07 | Pfizer Inc. | Rapamycin producer |
| CA2106034A1 (en) * | 1992-09-24 | 1994-03-25 | Ralph J. Russo | 21-norrapamycin |
| EP0854874B1 (en) * | 1994-11-10 | 2003-05-02 | Pfizer Inc. | Macrocyclic lactone compounds and their production process |
-
1995
- 1995-10-13 EP EP95932876A patent/EP0854874B1/en not_active Expired - Lifetime
- 1995-10-13 JP JP8515869A patent/JP3061863B2/ja not_active Expired - Lifetime
- 1995-10-13 CA CA002204739A patent/CA2204739C/en not_active Expired - Fee Related
- 1995-10-13 PT PT95932876T patent/PT854874E/pt unknown
- 1995-10-13 MX MX9703484A patent/MX9703484A/es not_active IP Right Cessation
- 1995-10-13 WO PCT/IB1995/000870 patent/WO1996015131A1/en not_active Ceased
- 1995-10-13 US US08/836,213 patent/US6001998A/en not_active Expired - Fee Related
- 1995-10-13 AT AT95932876T patent/ATE239024T1/de not_active IP Right Cessation
- 1995-10-13 ES ES95932876T patent/ES2194054T3/es not_active Expired - Lifetime
- 1995-10-13 DK DK95932876T patent/DK0854874T3/da active
- 1995-10-13 DE DE69530616T patent/DE69530616T2/de not_active Expired - Fee Related
- 1995-10-13 FI FI971995A patent/FI971995A0/fi not_active IP Right Cessation
-
1999
- 1999-08-20 US US09/378,062 patent/US6187568B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2204739C (en) | 2000-04-04 |
| MX9703484A (es) | 1997-08-30 |
| FI971995A7 (fi) | 1997-05-09 |
| JPH11507907A (ja) | 1999-07-13 |
| ES2194054T3 (es) | 2003-11-16 |
| DE69530616T2 (de) | 2004-04-01 |
| PT854874E (pt) | 2003-07-31 |
| EP0854874B1 (en) | 2003-05-02 |
| ATE239024T1 (de) | 2003-05-15 |
| US6001998A (en) | 1999-12-14 |
| DE69530616D1 (de) | 2003-06-05 |
| JP3061863B2 (ja) | 2000-07-10 |
| WO1996015131A1 (en) | 1996-05-23 |
| DK0854874T3 (da) | 2003-06-02 |
| FI971995A0 (fi) | 1997-05-09 |
| EP0854874A1 (en) | 1998-07-29 |
| US6187568B1 (en) | 2001-02-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Patent expired |