[go: up one dir, main page]

FI971000A0 - Kantasolujen jakautumista hidastava aine ja sen käyttö - Google Patents

Kantasolujen jakautumista hidastava aine ja sen käyttö

Info

Publication number
FI971000A0
FI971000A0 FI971000A FI971000A FI971000A0 FI 971000 A0 FI971000 A0 FI 971000A0 FI 971000 A FI971000 A FI 971000A FI 971000 A FI971000 A FI 971000A FI 971000 A0 FI971000 A0 FI 971000A0
Authority
FI
Finland
Prior art keywords
stem cell
inhibitor
cell division
disclosed
accelerating
Prior art date
Application number
FI971000A
Other languages
English (en)
Swedish (sv)
Other versions
FI971000L (fi
FI117468B (fi
Inventor
Vladimir Kozlov
Irena Tsyrlova
Stephen D Wolpe
Original Assignee
Pro Neuron Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/316,424 external-priority patent/US6022848A/en
Application filed by Pro Neuron Inc filed Critical Pro Neuron Inc
Publication of FI971000A0 publication Critical patent/FI971000A0/fi
Publication of FI971000L publication Critical patent/FI971000L/fi
Application granted granted Critical
Publication of FI117468B publication Critical patent/FI117468B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M11/00—Telephonic communication systems specially adapted for combination with other electrical systems
    • H04M11/002—Telephonic communication systems specially adapted for combination with other electrical systems with telemetering systems
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M11/00—Telephonic communication systems specially adapted for combination with other electrical systems
    • H04M11/04—Telephonic communication systems specially adapted for combination with other electrical systems with alarm systems, e.g. fire, police or burglar alarm systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Signal Processing (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
FI971000A 1994-09-30 1997-03-11 Kantasolujen lisääntymisen inhibiittoreita FI117468B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US08/316,424 US6022848A (en) 1993-03-31 1994-09-30 Inhibitor of stem cell proliferation and uses thereof
US31642494 1994-09-30
US08/535,882 US5939391A (en) 1993-03-31 1995-09-28 Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
US53588295 1995-09-28
PCT/US1995/012268 WO1996010634A1 (en) 1994-09-30 1995-09-29 Inhibitor of stem cell proliferation and uses thereof
US9512268 1995-09-29

Publications (3)

Publication Number Publication Date
FI971000A0 true FI971000A0 (fi) 1997-03-11
FI971000L FI971000L (fi) 1997-05-28
FI117468B FI117468B (fi) 2006-10-31

Family

ID=26980434

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971000A FI117468B (fi) 1994-09-30 1997-03-11 Kantasolujen lisääntymisen inhibiittoreita

Country Status (17)

Country Link
US (2) US5939391A (fi)
EP (1) EP0784677B1 (fi)
JP (3) JP3953511B2 (fi)
CN (2) CN1328285C (fi)
AT (1) ATE263236T1 (fi)
CA (1) CA2201105C (fi)
DE (1) DE69532813T2 (fi)
DK (1) DK0784677T3 (fi)
ES (1) ES2216019T3 (fi)
FI (1) FI117468B (fi)
IL (1) IL115473A (fi)
MX (1) MX9702266A (fi)
NO (1) NO319575B1 (fi)
NZ (2) NZ294446A (fi)
PT (1) PT784677E (fi)
RU (1) RU2186579C2 (fi)
WO (1) WO1996010634A1 (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939391A (en) * 1993-03-31 1999-08-17 Pro-Neuron, Inc. Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
US6610654B2 (en) 1993-03-31 2003-08-26 Wellstat Therapeutics Corporation Inhibitor of stem cell proliferation and uses thereof
WO1994022915A1 (en) 1993-03-31 1994-10-13 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
EP1897553A1 (en) * 1994-09-30 2008-03-12 Wellstat Therapeutics Corporation Inhibitor of stem cell proliferation and uses thereof
US5861483A (en) 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
GB9700154D0 (en) * 1997-01-07 1997-02-26 Primapharma Ltd Peptides
JP2000095794A (ja) * 1998-09-22 2000-04-04 Itoham Foods Inc エンケファリン分解酵素の阻害剤
US6488828B1 (en) * 2000-07-20 2002-12-03 Roche Diagnostics Corporation Recloseable biosensor
US20080220444A1 (en) * 2003-09-10 2008-09-11 Koratich Michael S Bone Marrow Proliferation Assay
AU2006276083B2 (en) * 2005-07-26 2012-04-19 Cms Peptides Patent Holding Company Limited Novel biologically active peptides and their new uses
RU2317074C1 (ru) * 2006-03-16 2008-02-20 Общество с ограниченной ответственностью "МБФ" Ингибитор дифференцировки кроветворных клеток-предшественников
RU2320364C1 (ru) * 2006-08-21 2008-03-27 Закрытое Акционерное Общество "Центр "Пептос" Способ лечения злокачественных новообразований
RU2328304C1 (ru) * 2007-03-22 2008-07-10 Общество с ограниченной ответственностью "Геленпол" Агент защиты клеток крови и восстановления кроветворной системы и фармакологическая комбинация для лечения онкологических больных
WO2008136699A1 (fr) * 2007-05-04 2008-11-13 Igor Alexandrovich Bazikov Patch transdermique à microcapsules et procédé de fabrication correspondant
US9782452B2 (en) * 2011-11-22 2017-10-10 Cornell University Methods for stimulating hematopoietic recovery by inhibiting TGFβ signaling
US9220706B2 (en) 2012-06-01 2015-12-29 National Institutes Of Health (Nih) Inhibition of leukemic stem cells by PP2A activating agents
WO2014078787A1 (en) * 2012-11-19 2014-05-22 Wellstat Therapeutics Corporation Stem cell mobilization and tissue repair and regeneration
RU2535972C2 (ru) * 2012-12-24 2014-12-20 Андрей Степанович БРЮХОВЕЦКИЙ Противоопухолевый индивидуальный протеом-основанный таргетный клеточный препарат, способ его получения и применение этого препарата для терапии рака и других злокачественных новообразований
RU2537141C1 (ru) * 2013-11-20 2014-12-27 государственное бюджетное образовательное учреждение высшего профессионального образования "Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Способ определения способности клеток костного мозга к делению
CN104817613A (zh) * 2014-01-30 2015-08-05 陈光健 寡肽cd06及其制备方法和应用
CN104817625A (zh) * 2014-01-30 2015-08-05 陈光健 寡肽cd03及其制备方法和应用
CN104817622A (zh) * 2014-01-30 2015-08-05 陈光健 寡肽cd04及其制备方法和应用
CN104817615A (zh) * 2014-01-30 2015-08-05 陈光健 寡肽cd05及其制备方法和应用
CN105294830A (zh) * 2014-06-18 2016-02-03 陈光健 一种二肽分子及其制备方法和应用
US10953107B2 (en) * 2018-06-15 2021-03-23 Trustees Of Boston University Polypeptide compositions and methods for site-specific targeting of therapeutic agents

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1142466A (en) * 1979-01-09 1983-03-08 Cesar Milstein Cell lines
US4683194A (en) * 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US5449759A (en) * 1987-05-16 1995-09-12 Somatogen, Inc. Hemoglobins with intersubunit desulfide bonds
GB8711614D0 (en) * 1987-05-16 1987-06-24 Medical Res Council Proteins
IE970086A1 (en) * 1989-05-10 2000-02-23 Somatogenetics Internat Inc Production in bacteria and yeast of hemoglobin and analogues thereof
US5545727A (en) * 1989-05-10 1996-08-13 Somatogen, Inc. DNA encoding fused di-alpha globins and production of pseudotetrameric hemoglobin
CA2064558C (en) * 1989-09-25 2001-01-30 Ian B. Pragnell Method for inhibiting growth of stem cells
US5239061A (en) * 1990-06-20 1993-08-24 Research Corporation Technologies, Inc. Modified human hemoglobin, blood substitutes containing the same, and vectors for expressing the modified hemoglobin
ATE206760T1 (de) * 1990-12-20 2001-10-15 Univ Alabama Res Found Transgenes, vernetztes hämoglobin
AU2140492A (en) * 1991-05-14 1992-12-30 Biopure Corporation Use of hemoglobin in a method for the treatment of tumors with chemotherapeutic agents
US5334706A (en) * 1992-01-30 1994-08-02 Baxter International Administration of low dose hemoglobin to increase perfusion
US5786334A (en) * 1992-08-14 1998-07-28 Technology Resources International, Inc. Hexapeptide having immunostimulatory activity
DE4228458A1 (de) * 1992-08-27 1994-06-01 Beiersdorf Ag Multicistronische Expressionseinheiten und deren Verwendung
US5939391A (en) * 1993-03-31 1999-08-17 Pro-Neuron, Inc. Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
US5861483A (en) * 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof

Also Published As

Publication number Publication date
CA2201105A1 (en) 1996-04-11
NZ335108A (en) 2000-11-24
JP4188279B2 (ja) 2008-11-26
NZ294446A (en) 1999-07-29
CN1328285C (zh) 2007-07-25
CA2201105C (en) 2009-11-24
DE69532813D1 (de) 2004-05-06
CN1565627A (zh) 2005-01-19
FI971000L (fi) 1997-05-28
NO319575B1 (no) 2005-08-29
ES2216019T3 (es) 2004-10-16
US6090782A (en) 2000-07-18
EP0784677A1 (en) 1997-07-23
EP0784677A4 (en) 2002-01-30
PT784677E (pt) 2004-08-31
JP2004256553A (ja) 2004-09-16
CN1321688C (zh) 2007-06-20
JP2008088186A (ja) 2008-04-17
HK1108701A1 (zh) 2008-05-16
ATE263236T1 (de) 2004-04-15
RU2186579C2 (ru) 2002-08-10
IL115473A (en) 2005-08-31
DK0784677T3 (da) 2004-08-02
WO1996010634A1 (en) 1996-04-11
US5939391A (en) 1999-08-17
HK1006642A1 (zh) 1999-03-12
IL115473A0 (en) 1995-12-31
JP3953511B2 (ja) 2007-08-08
FI117468B (fi) 2006-10-31
CN1168695A (zh) 1997-12-24
JPH10509422A (ja) 1998-09-14
EP0784677B1 (en) 2004-03-31
MX9702266A (es) 1997-06-28
DE69532813T2 (de) 2005-03-17
NO971444D0 (no) 1997-03-26
HK1071517A1 (en) 2005-07-22
NO971444L (no) 1997-05-26

Similar Documents

Publication Publication Date Title
FI971000A0 (fi) Kantasolujen jakautumista hidastava aine ja sen käyttö
ATE225370T1 (de) Inhibitor der stammzellproliferation und seine verwendung
NO984628L (no) Inhibitor og stimulator av stamcelleproliferasjon og anvendelser derav
PL331332A1 (en) Cell adhesion inhibitors
MY121222A (en) Prodrugs of thrombin inhibitors
NO20001583D0 (no) Stimulering av hematopoetiske celler in vitro
MX7113E (es) Procedimiento para aislar composiciones que contienen fibronectina,a partir de un crioprecipitado de plasma sanguineo
ES8302728A1 (es) Procedimiento para preparar derivados de prolina .
ZA919164B (en) Retroviral protease inhibitors.
NO992492L (no) Benzamidoaldehyder og deres anvendelse som cystein-protease-inhibitorer
ATE196637T1 (de) Dipeptidische benzamidine als kininogenasen- inhibitoren
TR199802676A2 (xx) T�m�rlerin, t�m�rle ilgili hastal�klar�n ve ka�eksinin tedavisi ve �nlenmesi i�in y�ntem.
BR9612360A (pt) Inibidores de amidino protease
NO934628L (no) Retrovirus-protease-inhibitorer
BG109411A (en) METHOD FOR OBTAINING HIV-PROTEZATE INHIBITORS
ES8205126A1 (es) Un procedimiento para la preparacion de un inhibidor del enzima convertidor de la angiotensina.
GB2080310B (en) Tripeptide inhibitors of angiotensin-converting enzyme
MY117925A (en) Compounds for the inhibition of farnesyl protein transferase.
JPS5581584A (en) Culture for isolating serratia
UA38590A (uk) Спосіб лікування гломерулонефриту з анефротичним синдромом та гематуричним компонентом
GEP20012440B (en) Biphenylsulfonamide Matrix Metalloproteinase Inhibitors

Legal Events

Date Code Title Description
FG Patent granted

Ref document number: 117468

Country of ref document: FI