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FI970740A0 - Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa - Google Patents

Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa

Info

Publication number
FI970740A0
FI970740A0 FI970740A FI970740A FI970740A0 FI 970740 A0 FI970740 A0 FI 970740A0 FI 970740 A FI970740 A FI 970740A FI 970740 A FI970740 A FI 970740A FI 970740 A0 FI970740 A0 FI 970740A0
Authority
FI
Finland
Prior art keywords
terpyridine
metal complexes
pct
preparation
functional
Prior art date
Application number
FI970740A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI970740A7 (fi
Inventor
Robert Haener
Jonathan Hall
Dieter Huesken
Uwe Pieles
Heinz Moser
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI970740A7 publication Critical patent/FI970740A7/fi
Publication of FI970740A0 publication Critical patent/FI970740A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/40—Rare earth chelates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Solid State Image Pick-Up Elements (AREA)
  • Transforming Light Signals Into Electric Signals (AREA)
  • Color Television Image Signal Generators (AREA)
  • Peptides Or Proteins (AREA)
FI970740A 1994-09-02 1997-02-21 Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa FI970740A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH269394 1994-09-02
PCT/EP1995/003409 WO1996007668A1 (fr) 1994-09-02 1995-08-30 Complexes terpyridine-metal fonctionnels, leur procede de fabrication et conjugues d'oligonucleotides comprenant des complexes terpyridine-metal

Publications (2)

Publication Number Publication Date
FI970740A7 FI970740A7 (fi) 1997-02-21
FI970740A0 true FI970740A0 (fi) 1997-02-21

Family

ID=4239459

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970740A FI970740A0 (fi) 1994-09-02 1997-02-21 Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa

Country Status (15)

Country Link
US (1) US5925744A (fr)
EP (1) EP0778844B1 (fr)
JP (1) JPH10505354A (fr)
AT (1) ATE229969T1 (fr)
AU (1) AU695749B2 (fr)
CA (1) CA2197788A1 (fr)
CY (1) CY2435B1 (fr)
DE (1) DE59510515D1 (fr)
DK (1) DK0778844T3 (fr)
ES (1) ES2191060T3 (fr)
FI (1) FI970740A0 (fr)
HU (1) HU217774B (fr)
NO (1) NO316866B1 (fr)
PT (1) PT778844E (fr)
WO (1) WO1996007668A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000514799A (ja) * 1996-07-03 2000-11-07 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ オリゴヌクレオチドリンカーおよび固定化および結合オリゴヌクレオチドを用いる技術
US6376664B1 (en) * 1999-03-17 2002-04-23 The Ohio State University Cyclic bis-benzimidazole ligands and metal complexes thereof
US6407089B1 (en) 1999-12-23 2002-06-18 Trinapco Inc. Triazatrinaphthyrins and the use thereof
EA007162B1 (ru) * 1999-12-23 2006-08-25 Трайнэпко, Инк. Триазатринафтирины и способ их получения, их соль, комплекс металла, способ и композиция для экстрагирования переходного металла
GB0007764D0 (en) * 2000-03-30 2000-05-17 Bp Chem Int Ltd Polymerisation catalyst
FR2810406B1 (fr) * 2000-06-15 2002-09-20 Cis Bio Int Nouveaux cryptates de terre rare peu sensibles a l'extinction de fluorescence
CN101437943A (zh) 2006-05-03 2009-05-20 波罗的科技发展有限公司 牢固结合的碱基-修饰的寡核苷酸和人工核酸酶组合的反义药剂
ES2595031T5 (es) 2008-05-27 2020-05-28 Dako Denmark As Composiciones y métodos para la detección de aberraciones cromosómicas con tampones de hibridación novedosos
EP2401396B1 (fr) 2009-02-26 2016-11-23 Dako Denmark A/S Procédés pour effectuer une étape de lavage stringent dans des applications d'hybridation
US20110151457A1 (en) 2009-12-22 2011-06-23 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
EP2761028A1 (fr) 2011-09-30 2014-08-06 Dako Denmark A/S Compositions d'hybridation et procédés utilisant du formamide
WO2013057310A2 (fr) 2011-10-21 2013-04-25 Dako Denmark A/S Compositions et procédés d'hybridation
CN114315702A (zh) * 2022-02-11 2022-04-12 南京邮电大学 一种基于低维镧系金属配合物X射线激发闪烁体Eu-TPC及其制备方法
CN115819474A (zh) * 2022-12-22 2023-03-21 苏州泓迅生物科技股份有限公司 一种可双端共轭不同化合物的核酸及其合成方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806463A (en) * 1986-05-23 1989-02-21 Worcester Foundation For Experimental Biology Inhibition of HTLV-III by exogenous oligonucleotides
EP0266099A3 (fr) * 1986-10-28 1990-09-19 The Johns Hopkins University Alkyl- ou arylphosphonate oligonucléoside capable de réticulation avec des acides nucléiques ou de clevage d'acides nucléiques
AU636573B2 (en) * 1988-02-26 1993-05-06 Worcester Foundation For Biomedical Research, Inc. Inhibition of htlv-iii by exogenous oligonucleotides
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis
US5760191A (en) * 1993-02-05 1998-06-02 Nycomed Imaging As Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods

Also Published As

Publication number Publication date
FI970740A7 (fi) 1997-02-21
HUT77933A (hu) 1998-11-30
EP0778844B1 (fr) 2002-12-18
AU3474495A (en) 1996-03-27
AU695749B2 (en) 1998-08-20
WO1996007668A1 (fr) 1996-03-14
DE59510515D1 (de) 2003-01-30
HU217774B (hu) 2000-04-28
NO316866B1 (no) 2004-06-07
JPH10505354A (ja) 1998-05-26
CY2435B1 (en) 2004-11-12
EP0778844A1 (fr) 1997-06-18
NO970886D0 (no) 1997-02-27
DK0778844T3 (da) 2003-03-31
US5925744A (en) 1999-07-20
NO970886L (no) 1997-04-25
CA2197788A1 (fr) 1996-03-14
ATE229969T1 (de) 2003-01-15
PT778844E (pt) 2003-04-30
ES2191060T3 (es) 2003-09-01

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