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FI941732L - Fukosyloitujen hiilihydraattien valmistaminen sokerinukleotidien entsymaattisella fukosylointisyteesillä ja GDP-fukoosin in situ regenerointi - Google Patents

Fukosyloitujen hiilihydraattien valmistaminen sokerinukleotidien entsymaattisella fukosylointisyteesillä ja GDP-fukoosin in situ regenerointi Download PDF

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Publication number
FI941732L
FI941732L FI941732A FI941732A FI941732L FI 941732 L FI941732 L FI 941732L FI 941732 A FI941732 A FI 941732A FI 941732 A FI941732 A FI 941732A FI 941732 L FI941732 L FI 941732L
Authority
FI
Finland
Prior art keywords
gdp
fucose
preparation
situ regeneration
sugar nucleotides
Prior art date
Application number
FI941732A
Other languages
English (en)
Swedish (sv)
Other versions
FI941732A0 (fi
FI941732A7 (fi
Inventor
Chi-Huey Wong
Yoshitaka Ichikawa
Gwo-Jenn Shen
Kun-Chin Liu
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/961,076 external-priority patent/US6319695B1/en
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of FI941732A0 publication Critical patent/FI941732A0/fi
Publication of FI941732A7 publication Critical patent/FI941732A7/fi
Publication of FI941732L publication Critical patent/FI941732L/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
FI941732A 1991-10-15 1992-10-15 Fukosyloitujen hiilihydraattien valmistaminen sokerinukleotidien entsymaattisella fukosylointisyteesillä ja GDP-fukoosin in situ regenerointi FI941732L (fi)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77766291A 1991-10-15 1991-10-15
US90126092A 1992-06-19 1992-06-19
US91061292A 1992-07-08 1992-07-08
US07/961,076 US6319695B1 (en) 1991-10-15 1992-10-14 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
PCT/US1992/008789 WO1993008205A1 (en) 1991-10-15 1992-10-15 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose

Publications (3)

Publication Number Publication Date
FI941732A0 FI941732A0 (fi) 1994-04-14
FI941732A7 FI941732A7 (fi) 1994-06-14
FI941732L true FI941732L (fi) 1994-06-14

Family

ID=27505746

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941732A FI941732L (fi) 1991-10-15 1992-10-15 Fukosyloitujen hiilihydraattien valmistaminen sokerinukleotidien entsymaattisella fukosylointisyteesillä ja GDP-fukoosin in situ regenerointi

Country Status (13)

Country Link
US (2) US6518418B1 (fi)
EP (1) EP0642526B1 (fi)
JP (1) JPH07500248A (fi)
AT (1) ATE174925T1 (fi)
AU (1) AU675209B2 (fi)
BG (1) BG98713A (fi)
CA (1) CA2121365C (fi)
DE (1) DE69228005T2 (fi)
ES (1) ES2129458T3 (fi)
FI (1) FI941732L (fi)
RO (1) RO118132B1 (fi)
SK (1) SK42594A3 (fi)
WO (1) WO1993008205A1 (fi)

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WO1993008205A1 (en) 1991-10-15 1993-04-29 The Scripps Research Institute Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose
IT1268954B1 (it) * 1994-03-11 1997-03-18 Fidia Advanced Biopolymers Srl Processo per la preparazione di acido ialuronico mediante sintesienzimatica e relative composizioni farmaceutiche
CN1200765A (zh) * 1996-09-11 1998-12-02 山佐酱油株式会社 糖核苷酸的制备方法
JP3545424B2 (ja) * 1996-11-19 2004-07-21 ヤマサ醤油株式会社 ヌクレオシド５’−トリリン酸の製造法及びその応用
US6274725B1 (en) 1998-06-02 2001-08-14 Isis Pharmaceuticals, Inc. Activators for oligonucleotide synthesis
DE19908712C2 (de) * 1999-03-01 2002-02-07 Forschungszentrum Juelich Gmbh Verfahren zur Herstellung eines ·1··8·F-markierten Glykosylierungsreagenz
JP5624535B2 (ja) 2008-05-02 2014-11-12 シアトル ジェネティクス，インコーポレーテッド 低いコアフコシル化を有する抗体及び抗体誘導体を調製するための方法並びに組成物
TR201902439T4 (tr) 2010-08-05 2019-03-21 Seattle Genetics Inc Fukoz analogları kullanarak in vivo protein fukosilasyonunun inhibisyon yöntemleri .
CN103429604A (zh) * 2011-02-21 2013-12-04 格礼卡姆股份公司 寡糖前体的混合物的组合物的催化氢解及其用途
CN103597088B (zh) * 2011-06-09 2018-01-02 三洋化成工业株式会社 多糖的制造方法
CA2882725C (en) 2012-08-23 2021-03-09 Regents Of The University Of Minnesota Treatment of sickle cell disease and inflammatory conditions
CN104876977A (zh) * 2013-07-17 2015-09-02 张家港威胜生物医药有限公司 一种制备1-溴-2,3,4,6-四-O-乙酰基-α-D-吡喃葡萄糖的方法
CA3031802A1 (en) 2016-08-13 2018-02-22 Zymtronix Catalytic Systems, Inc. Magnetically immobilized biocidal enzymes and biocidal chemicals
CN108251474A (zh) * 2018-01-15 2018-07-06 山东大学 Abh人血型抗原的合成方法
TW202023625A (zh) 2018-08-23 2020-07-01 美商西雅圖遺傳學公司 抗tigit抗體
EP3719135A1 (en) * 2019-04-01 2020-10-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Enzymatic method for preparation of gdp-fucose
US20230279403A1 (en) * 2020-08-10 2023-09-07 Inbiose N.V. Production of alpha-1,3 glycosylated form of fuc-a1,2-gal-r
CN112915565B (zh) * 2021-03-04 2022-04-08 安徽金禾实业股份有限公司 一种旋转式蔗糖-6-酯连续生产设备及生产方法
CN114990175B (zh) * 2021-10-22 2023-03-31 岩唐生物科技(杭州)有限责任公司 一种岩藻糖衍生物的合成方法
CN113960232B (zh) * 2021-10-28 2024-02-20 苏州大学 一种基于唾液特异性岩藻糖基化结构糖谱及其检测方法和应用
EP4526315A1 (en) * 2022-05-18 2025-03-26 Glycomine, Inc. Continuous flow methods for producing mannose-1-phosphate, polymorphs of mannose-1-phosphate, and compositions and uses related thereto
CN119546773A (zh) * 2022-05-20 2025-02-28 齐姆特罗尼克斯催化系统股份有限公司 寡糖和衍生物从单糖的生物制造

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Also Published As

Publication number Publication date
SK42594A3 (en) 1994-10-05
ES2129458T3 (es) 1999-06-16
US20020068331A1 (en) 2002-06-06
US6518418B1 (en) 2003-02-11
RO118132B1 (ro) 2003-02-28
CA2121365A1 (en) 1993-04-29
AU2785492A (en) 1993-05-21
EP0642526A1 (en) 1995-03-15
FI941732A0 (fi) 1994-04-14
WO1993008205A1 (en) 1993-04-29
ATE174925T1 (de) 1999-01-15
EP0642526A4 (en) 1996-04-10
EP0642526B1 (en) 1998-12-23
DE69228005T2 (de) 1999-07-15
AU675209B2 (en) 1997-01-30
FI941732A7 (fi) 1994-06-14
DE69228005D1 (de) 1999-02-04
JPH07500248A (ja) 1995-01-12
BG98713A (bg) 1995-05-31
US7335500B2 (en) 2008-02-26
CA2121365C (en) 2000-11-28

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