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FI903818A7 - 1-(pyridinylamino)-2-pyrrolidones, process for their preparation and their use as pharmaceuticals - Google Patents

1-(pyridinylamino)-2-pyrrolidones, process for their preparation and their use as pharmaceuticals Download PDF

Info

Publication number
FI903818A7
FI903818A7 FI903818A FI903818A FI903818A7 FI 903818 A7 FI903818 A7 FI 903818A7 FI 903818 A FI903818 A FI 903818A FI 903818 A FI903818 A FI 903818A FI 903818 A7 FI903818 A7 FI 903818A7
Authority
FI
Finland
Prior art keywords
pyridinylamino
pyrrolidones
pharmaceuticals
preparation
Prior art date
Application number
FI903818A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI903818A0 (en
Inventor
David Gordon Wettlaufer
Richard Charles Effland
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI903818A0 publication Critical patent/FI903818A0/en
Publication of FI903818A7 publication Critical patent/FI903818A7/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI903818A 1989-08-02 1990-07-31 1-(pyridinylamino)-2-pyrrolidones, process for their preparation and their use as pharmaceuticals FI903818A7 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/388,413 US4994472A (en) 1989-08-02 1989-08-02 1-(pyridinylamino)-2-pyrrolidinones as pain relievers

Publications (2)

Publication Number Publication Date
FI903818A0 FI903818A0 (en) 1990-07-31
FI903818A7 true FI903818A7 (en) 1991-02-03

Family

ID=23534027

Family Applications (1)

Application Number Title Priority Date Filing Date
FI903818A FI903818A7 (en) 1989-08-02 1990-07-31 1-(pyridinylamino)-2-pyrrolidones, process for their preparation and their use as pharmaceuticals

Country Status (17)

Country Link
US (1) US4994472A (en)
EP (1) EP0413191B1 (en)
JP (1) JPH0674264B2 (en)
KR (1) KR0164437B1 (en)
AT (1) ATE109142T1 (en)
AU (1) AU635051B2 (en)
CA (1) CA2022484C (en)
DE (1) DE69011013T2 (en)
DK (1) DK0413191T3 (en)
ES (1) ES2059929T3 (en)
FI (1) FI903818A7 (en)
IE (1) IE65117B1 (en)
IL (1) IL95250A (en)
NO (1) NO903388L (en)
NZ (1) NZ234724A (en)
PT (1) PT94878B (en)
ZA (1) ZA906049B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356908A (en) * 1989-04-21 1994-10-18 E. I. Du Pont De Nemours And Company Fungicidal oxazolidinones
DK0435843T3 (en) * 1989-12-27 1994-07-04 Monsanto Co Substituted pyridine compounds
AUPM656594A0 (en) * 1994-06-30 1994-07-21 Orbital Engine Company (Australia) Proprietary Limited A method and apparatus relating to control of the operation of an internal combustion engine
DK0892796T3 (en) * 1996-04-12 2001-11-19 Aventis Pharma Inc Isatin derivatives such as acetylcholinesterase inhibitors and analgesics
US6100276A (en) * 1996-04-12 2000-08-08 Aventis Pharmaceuticals Inc. Isatin derivatives as acetylcholinesterase inhibitors and analgesics
WO2004004641A2 (en) * 2002-07-02 2004-01-15 Blanchette Rockefeller Neurosciences Institute PKC ACTIVATION AS A MEANS FOR ENHANCING sAPPα SECRETION AND IMPROVING COGNITION USING BRYOSTATIN TYPE COMPOUNDS
US20050065205A1 (en) 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
TW201206425A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Treatment of depressive disorders
GB0412019D0 (en) * 2004-05-28 2004-06-30 Novartis Ag Organic compounds
WO2007016202A1 (en) 2005-07-29 2007-02-08 Blanchette Rockefeller Neurosciences Institute Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory
WO2008100449A2 (en) 2007-02-09 2008-08-21 Blanchette Rockefeller Neurosciences Institute Therapeutic effects of bryostatins, bryologs, and other related substances on head trauma-induced memory impairment and brain injury

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670184A1 (en) * 1967-01-20 1971-01-21 Boehringer Sohn Ingelheim Process for the preparation of heterocyclically substituted hydrazino-imidazoline- (2)
US4260767A (en) * 1979-12-26 1981-04-07 American Cyanamid Company 2-Pyridylhydrazides
US4324884A (en) * 1980-09-25 1982-04-13 General Electric Company Organic amine catalyzed method for making polyetherimide
US4752610A (en) * 1985-12-04 1988-06-21 Hoechst-Roussel Pharmaceuticals Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing properties
US4792562A (en) * 1985-12-04 1988-12-20 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing activity
JPH0699307B2 (en) * 1987-08-20 1994-12-07 キッセイ薬品工業株式会社 Anti-dementia agent
US4868190A (en) * 1988-12-27 1989-09-19 Hoechst-Roussel Pharmaceuticals, Inc. N-pyridinyl-9H-carbazol-9-amines

Also Published As

Publication number Publication date
DK0413191T3 (en) 1994-10-24
IL95250A0 (en) 1991-06-10
KR910004597A (en) 1991-03-29
CA2022484A1 (en) 1991-02-03
AU6000290A (en) 1991-02-07
JPH0674264B2 (en) 1994-09-21
CA2022484C (en) 2000-10-17
IE65117B1 (en) 1995-10-04
DE69011013D1 (en) 1994-09-01
IE902786A1 (en) 1991-02-27
PT94878A (en) 1991-04-18
NZ234724A (en) 1992-01-29
NO903388D0 (en) 1990-08-01
ES2059929T3 (en) 1994-11-16
DE69011013T2 (en) 1994-12-22
NO903388L (en) 1991-02-04
PT94878B (en) 1997-08-29
ZA906049B (en) 1991-04-24
JPH0368572A (en) 1991-03-25
KR0164437B1 (en) 1999-01-15
IL95250A (en) 1994-01-25
FI903818A0 (en) 1990-07-31
EP0413191A1 (en) 1991-02-20
ATE109142T1 (en) 1994-08-15
US4994472A (en) 1991-02-19
EP0413191B1 (en) 1994-07-27
AU635051B2 (en) 1993-03-11

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED