FI906008A0 - Menetelmä heterosyklisen yhdisteen vesipitoisen seoksen stabiloimiseksi - Google Patents
Menetelmä heterosyklisen yhdisteen vesipitoisen seoksen stabiloimiseksiInfo
- Publication number
- FI906008A0 FI906008A0 FI906008A FI906008A FI906008A0 FI 906008 A0 FI906008 A0 FI 906008A0 FI 906008 A FI906008 A FI 906008A FI 906008 A FI906008 A FI 906008A FI 906008 A0 FI906008 A0 FI 906008A0
- Authority
- FI
- Finland
- Prior art keywords
- methionine
- stabilizing
- heterocyclic compound
- stabilized
- aqueous mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000087 stabilizing effect Effects 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 2
- 239000000935 antidepressant agent Substances 0.000 abstract 2
- 229940005513 antidepressants Drugs 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 abstract 1
- 229930182818 D-methionine Natural products 0.000 abstract 1
- 239000004470 DL Methionine Substances 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 229930195722 L-methionine Natural products 0.000 abstract 1
- UEQUQVLFIPOEMF-UHFFFAOYSA-N Mianserin Chemical compound C1C2=CC=CC=C2N2CCN(C)CC2C2=CC=CC=C21 UEQUQVLFIPOEMF-UHFFFAOYSA-N 0.000 abstract 1
- 229960000836 amitriptyline Drugs 0.000 abstract 1
- KRMDCWKBEZIMAB-UHFFFAOYSA-N amitriptyline Chemical compound C1CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 KRMDCWKBEZIMAB-UHFFFAOYSA-N 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 229960004452 methionine Drugs 0.000 abstract 1
- 235000006109 methionine Nutrition 0.000 abstract 1
- 229960003955 mianserin Drugs 0.000 abstract 1
- 229960001785 mirtazapine Drugs 0.000 abstract 1
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
- -1 septiline Chemical compound 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP89203092 | 1989-12-06 | ||
| EP89203092 | 1989-12-06 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI906008A0 true FI906008A0 (fi) | 1990-12-05 |
| FI906008L FI906008L (fi) | 1991-06-07 |
| FI97689B FI97689B (fi) | 1996-10-31 |
| FI97689C FI97689C (fi) | 1997-02-10 |
Family
ID=8202518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI906008A FI97689C (fi) | 1989-12-06 | 1990-12-05 | Menetelmä heterosyklisen yhdisteen vesipitoisen seoksen stabiloimiseksi |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5082864A (fi) |
| EP (1) | EP0431663B1 (fi) |
| JP (1) | JP2977912B2 (fi) |
| KR (1) | KR0185377B1 (fi) |
| AT (1) | ATE99943T1 (fi) |
| AU (1) | AU628768B2 (fi) |
| CA (1) | CA2030773C (fi) |
| DE (1) | DE69005992T2 (fi) |
| DK (1) | DK0431663T3 (fi) |
| ES (1) | ES2062310T3 (fi) |
| FI (1) | FI97689C (fi) |
| IE (1) | IE63985B1 (fi) |
| NZ (1) | NZ236332A (fi) |
| PT (1) | PT96096B (fi) |
| ZA (1) | ZA909568B (fi) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USH1591H (en) * | 1992-10-09 | 1996-09-03 | Fulcher; John | Preparation of flavor-enhanced reduced calorie fried foods |
| IL107887A (en) * | 1992-12-08 | 2003-07-06 | Ambi Inc | Stabilized lanthionine containing bacteriocin compositions |
| US6197830B1 (en) | 1995-09-22 | 2001-03-06 | Bruce M. Frome | Method for achieving relief from sympathetically mediated pain |
| IL121076A (en) * | 1996-06-19 | 2000-10-31 | Akzo Nobel Nv | Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors |
| EP0813873B1 (en) * | 1996-06-19 | 2002-02-13 | Akzo Nobel N.V. | Pharmaceutical composition comprising mirtazapine and one or more selective serotonin reuptake inhibitors |
| IL123716A (en) * | 1997-03-27 | 2001-03-19 | Akzo Nobel Nv | Therapeutic combinations of mirtazapine and an antipsychotic agent |
| AU747975B2 (en) * | 1998-04-02 | 2002-05-30 | N.V. Organon | Oral liquid antidepressant solution |
| US6211171B1 (en) | 1998-05-19 | 2001-04-03 | Dalhousie University | Use of antidepressants for local analgesia |
| US6495534B2 (en) | 2000-05-15 | 2002-12-17 | Pharmacia & Upjohn Spa | Stabilized aqueous suspensions for parenteral use |
| US6399310B1 (en) | 2001-02-12 | 2002-06-04 | Akzo Nobel N.V. | Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4 |
| US20030105082A1 (en) * | 2001-12-03 | 2003-06-05 | Murphy Greer Marechal | Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4 |
| US20040106124A1 (en) * | 2001-02-12 | 2004-06-03 | Murphy Greer M. | Methods for improving the treatment of major depression by genotyping for the gene for apolipoproteine e4 and for improving the terapeutic response of humans having major depression and carrying the gene for apolipoprotein e4 |
| US20050215552A1 (en) * | 2002-05-17 | 2005-09-29 | Gadde Kishore M | Method for treating obesity |
| MXPA05011557A (es) | 2003-04-29 | 2006-03-09 | Orexigen Therapeutics Inc | Composiciones para afectar perdida de peso. |
| US7838029B1 (en) | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| JP2007517901A (ja) * | 2004-01-13 | 2007-07-05 | デューク・ユニバーシティー | 体重の減少に作用する鎮痙剤及び抗精神病剤の組成物 |
| WO2006023703A2 (en) * | 2004-08-20 | 2006-03-02 | Cypress Bioscience, Inc. | Method for treating sleep related breathing disorders |
| WO2006031720A2 (en) * | 2004-09-14 | 2006-03-23 | Molecular Therapeutics, Inc. | D-methionine formulation with improved biopharmaceutical properties |
| US20060122127A1 (en) * | 2004-11-17 | 2006-06-08 | Cypress Bioscience, Inc. | Methods for reducing the side effects associated with mirtzapine treatment |
| JP5180092B2 (ja) | 2005-11-22 | 2013-04-10 | オレキシジェン・セラピューティクス・インコーポレーテッド | インスリン感受性を増すための組成物および方法 |
| EP1981478A2 (en) * | 2006-01-17 | 2008-10-22 | Regents of the University of Colorado | Central administration of stable formulations of therapeutic agents for cns conditions |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| MX343867B (es) * | 2006-11-09 | 2016-11-25 | Orexigen Therapeutics Inc | Paquete de dosificacion unitaria y metodos para administrar medicaciones de perdida de peso. |
| KR101654176B1 (ko) | 2006-11-09 | 2016-09-09 | 오렉시젠 세러퓨틱스 인크. | 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형 |
| WO2008157094A1 (en) * | 2007-06-13 | 2008-12-24 | Cypress Bioscience, Inc. | Improving the tolerability of mirtazapine and a second active by using them in combination |
| MX2010012909A (es) | 2008-05-30 | 2011-02-25 | Orexigen Therapeutics Inc | Metodos para tratamiento de condiciones de grasa visceral. |
| EP2523557B1 (en) | 2010-01-11 | 2019-09-25 | Nalpropion Pharmaceuticals, Inc. | Methods of providing weight loss therapy in patients with major depression |
| PL4104824T3 (pl) | 2012-06-06 | 2025-11-12 | Nalpropion Pharmaceuticals Llc | Kompozycja do zastosowania w sposobie leczenia nadwagi i otyłości u pacjentów z wysokim ryzykiem sercowo-naczyniowym |
| KR101652081B1 (ko) | 2014-12-30 | 2016-08-30 | 김인호 | 전극보일러 급탕시스템 |
| US10603272B2 (en) | 2015-02-27 | 2020-03-31 | Kindred Biosciences, Inc. | Stimulation of appetite and treatment of anorexia in dogs and cats |
| KR20170001494A (ko) | 2015-06-26 | 2017-01-04 | 김인호 | 전극보일러 전류제어시스템 |
| CN108853042B (zh) * | 2018-09-20 | 2021-03-26 | 北京哈三联科技有限责任公司 | 一种米氮平冻干口崩片及其制备方法和应用 |
| GR1009883B (el) * | 2019-06-07 | 2020-12-11 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαρμοσμενης Ερευνας Και Αναπτυξης Α.Ε. | Ποσιμα φαρμακευτικα διαλυματα που περιλαμβανουν υδροχλωρικη νορτριπτυλινη |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2082910A (en) * | 1980-08-28 | 1982-03-17 | Berk Pharmaceuticals Ltd | Anti-depressant compositions |
| US4603131A (en) * | 1982-04-26 | 1986-07-29 | Bernstein Joel E | Method and composition for treating and preventing irritation of the mucous membranes of the nose |
| DE3247676A1 (de) * | 1982-12-23 | 1984-06-28 | A. Nattermann & Cie GmbH, 5000 Köln | Galenische form fuer amitriptylinoxid und verfahren zur herstellung |
-
1990
- 1990-11-20 EP EP90203064A patent/EP0431663B1/en not_active Expired - Lifetime
- 1990-11-20 DK DK90203064.2T patent/DK0431663T3/da active
- 1990-11-20 ES ES90203064T patent/ES2062310T3/es not_active Expired - Lifetime
- 1990-11-20 DE DE90203064T patent/DE69005992T2/de not_active Expired - Lifetime
- 1990-11-20 AT AT90203064T patent/ATE99943T1/de not_active IP Right Cessation
- 1990-11-22 IE IE422690A patent/IE63985B1/en not_active IP Right Cessation
- 1990-11-23 CA CA002030773A patent/CA2030773C/en not_active Expired - Fee Related
- 1990-11-28 ZA ZA909568A patent/ZA909568B/xx unknown
- 1990-12-03 US US07/621,480 patent/US5082864A/en not_active Expired - Lifetime
- 1990-12-04 NZ NZ236332A patent/NZ236332A/en unknown
- 1990-12-05 PT PT96096A patent/PT96096B/pt not_active IP Right Cessation
- 1990-12-05 FI FI906008A patent/FI97689C/fi active IP Right Grant
- 1990-12-05 KR KR1019900019904A patent/KR0185377B1/ko not_active Expired - Fee Related
- 1990-12-05 AU AU67798/90A patent/AU628768B2/en not_active Ceased
- 1990-12-06 JP JP2413592A patent/JP2977912B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69005992D1 (de) | 1994-02-24 |
| JP2977912B2 (ja) | 1999-11-15 |
| CA2030773C (en) | 2001-07-24 |
| FI97689C (fi) | 1997-02-10 |
| AU628768B2 (en) | 1992-09-17 |
| IE63985B1 (en) | 1995-06-28 |
| PT96096B (pt) | 1998-02-27 |
| FI97689B (fi) | 1996-10-31 |
| DE69005992T2 (de) | 1994-05-05 |
| FI906008L (fi) | 1991-06-07 |
| DK0431663T3 (da) | 1994-03-07 |
| US5082864A (en) | 1992-01-21 |
| KR910011250A (ko) | 1991-08-07 |
| IE904226A1 (en) | 1991-06-19 |
| ATE99943T1 (de) | 1994-01-15 |
| EP0431663B1 (en) | 1994-01-12 |
| NZ236332A (en) | 1992-07-28 |
| PT96096A (pt) | 1991-09-30 |
| AU6779890A (en) | 1991-06-13 |
| ZA909568B (en) | 1991-09-25 |
| JPH05262651A (ja) | 1993-10-12 |
| ES2062310T3 (es) | 1994-12-16 |
| KR0185377B1 (ko) | 1999-05-01 |
| EP0431663A1 (en) | 1991-06-12 |
| CA2030773A1 (en) | 1991-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| FG | Patent granted |
Owner name: AKZO N.V. |
|
| PC | Transfer of assignment of patent |
Owner name: N.V. ORGANON Free format text: N.V. ORGANON |