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FI890611A7 - 3'-deamino-4'-deoksi-4'-amino-antrasykliinit - Google Patents

3'-deamino-4'-deoksi-4'-amino-antrasykliinit Download PDF

Info

Publication number
FI890611A7
FI890611A7 FI890611A FI890611A FI890611A7 FI 890611 A7 FI890611 A7 FI 890611A7 FI 890611 A FI890611 A FI 890611A FI 890611 A FI890611 A FI 890611A FI 890611 A7 FI890611 A7 FI 890611A7
Authority
FI
Finland
Prior art keywords
deamino
anthracyclines
deoxy
amino
Prior art date
Application number
FI890611A
Other languages
English (en)
Swedish (sv)
Other versions
FI890611A0 (fi
FI890611L (fi
Inventor
Antonino Suarato
Pier Angelo Zini
Gabriella Pezzoni
Maria Grandi
Alberto Bargiotti
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI890611A0 publication Critical patent/FI890611A0/fi
Publication of FI890611A7 publication Critical patent/FI890611A7/fi
Publication of FI890611L publication Critical patent/FI890611L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Pyrane Compounds (AREA)
FI890611A 1988-02-10 1989-02-09 3'-deamino-4'-deoxi-4'-amino -antracykliner. FI890611L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888803076A GB8803076D0 (en) 1988-02-10 1988-02-10 3'-deamino-4'-deoxy-4'-amino anthracyclines

Publications (3)

Publication Number Publication Date
FI890611A0 FI890611A0 (fi) 1989-02-09
FI890611A7 true FI890611A7 (fi) 1989-08-11
FI890611L FI890611L (fi) 1989-08-11

Family

ID=10631459

Family Applications (1)

Application Number Title Priority Date Filing Date
FI890611A FI890611L (fi) 1988-02-10 1989-02-09 3'-deamino-4'-deoxi-4'-amino -antracykliner.

Country Status (20)

Country Link
US (1) US4987126A (fi)
EP (1) EP0328400B1 (fi)
JP (1) JPH01294669A (fi)
KR (1) KR890013047A (fi)
CN (1) CN1037904A (fi)
AT (1) ATE88478T1 (fi)
AU (1) AU2974489A (fi)
CA (1) CA1338712C (fi)
DE (1) DE68906045T2 (fi)
DK (1) DK59289A (fi)
ES (1) ES2055035T3 (fi)
FI (1) FI890611L (fi)
GB (1) GB8803076D0 (fi)
HU (1) HUT49365A (fi)
IL (1) IL89199A0 (fi)
NO (1) NO890567L (fi)
NZ (1) NZ227877A (fi)
PT (1) PT89662B (fi)
YU (1) YU31189A (fi)
ZA (1) ZA891019B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
US5412081A (en) * 1989-02-07 1995-05-02 Farmitalia Carlo Erba S.R.L. New 4'-epi-4'-amino anthracyclines
GB8902709D0 (en) * 1989-02-07 1989-03-30 Erba Carlo Spa New 4'-epi-4'-amino anthracyclines
IT1241927B (it) * 1990-05-14 1994-02-01 Menarini Farma Ind 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
GB9028105D0 (en) * 1990-12-27 1991-02-13 Erba Carlo Spa Process for the preparation of substituted benzofuran derivatives
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
JPH0912590A (ja) * 1995-06-23 1997-01-14 Microbial Chem Res Found ４−アミノ−２，４，６−トリデオキシ−２−フルオロ−マンノピラノシル基を有する新規アンスラサイクリン誘導体
JPH10175992A (ja) * 1996-12-16 1998-06-30 Microbial Chem Res Found ４−アミノ−２，４，６−トリデオキシ−２−フルオロ−α−Ｌ−タロピラノシル基を有する新規アンスラサイクリン誘導体
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
US7381721B2 (en) * 2003-03-17 2008-06-03 Adolor Corporation Substituted piperidine compounds
US6992090B2 (en) * 2003-06-16 2006-01-31 Adolor Corporation Substituted piperidine compounds and methods of their use
US8946262B2 (en) * 2003-12-04 2015-02-03 Adolor Corporation Methods of preventing and treating gastrointestinal dysfunction
US7087749B2 (en) * 2004-03-11 2006-08-08 Adolor Corporation Substituted piperidine compounds and methods of their use
US20060063792A1 (en) * 2004-09-17 2006-03-23 Adolor Corporation Substituted morphinans and methods of their use
US7538110B2 (en) * 2005-10-27 2009-05-26 Adolor Corporation Opioid antagonists
AU2009214500B2 (en) 2008-02-14 2014-10-23 Alkermes, Inc. Selective opioid compounds
US20100311782A1 (en) 2009-06-08 2010-12-09 Adolor Corporation Substituted piperidinylpropanoic acid compounds and methods of their use
CN102115483B (zh) * 2009-12-30 2014-12-17 苏州天人合生物技术有限公司 卤代双去氧糖衍生物及其制备方法与应用
CN105582094B (zh) * 2016-03-11 2019-09-27 沈宁 一种治疗肾阴虚证的中药组合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
JPS57106695A (en) * 1980-11-01 1982-07-02 Erba Carlo Spa Anthracycline g lycoside compound
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same

Also Published As

Publication number Publication date
NO890567D0 (no) 1989-02-09
DK59289A (da) 1989-08-11
DE68906045T2 (de) 1993-08-05
CA1338712C (en) 1996-11-12
GB8803076D0 (en) 1988-03-09
DK59289D0 (da) 1989-02-09
ES2055035T3 (es) 1994-08-16
EP0328400B1 (en) 1993-04-21
YU31189A (en) 1991-02-28
ATE88478T1 (de) 1993-05-15
EP0328400A3 (en) 1989-11-08
IL89199A0 (en) 1989-09-10
HUT49365A (en) 1989-09-28
KR890013047A (ko) 1989-09-21
US4987126A (en) 1991-01-22
NZ227877A (en) 1990-05-28
FI890611A0 (fi) 1989-02-09
CN1037904A (zh) 1989-12-13
JPH01294669A (ja) 1989-11-28
EP0328400A2 (en) 1989-08-16
NO890567L (no) 1989-08-11
FI890611L (fi) 1989-08-11
AU2974489A (en) 1989-08-10
DE68906045D1 (en) 1993-05-27
PT89662A (pt) 1989-10-04
ZA891019B (en) 1989-10-25
PT89662B (pt) 1994-02-28

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: FARMITALIA CARLO ERBA S.R.L