[go: up one dir, main page]

FI894812L - Menetelmä valmistaa farmakologisesti arvokkaita 2-karbonyylisubstituoituja N,N'-di(trimetoksibentsoyyli)piperatsiineja - Google Patents

Menetelmä valmistaa farmakologisesti arvokkaita 2-karbonyylisubstituoituja N,N'-di(trimetoksibentsoyyli)piperatsiineja Download PDF

Info

Publication number
FI894812L
FI894812L FI894812A FI894812A FI894812L FI 894812 L FI894812 L FI 894812L FI 894812 A FI894812 A FI 894812A FI 894812 A FI894812 A FI 894812A FI 894812 L FI894812 L FI 894812L
Authority
FI
Finland
Prior art keywords
trimethoxybenzoyl
piperazines
carbonyl
substituted
pharmacologically valuable
Prior art date
Application number
FI894812A
Other languages
English (en)
Swedish (sv)
Other versions
FI96854B (fi
FI894812A0 (fi
FI96854C (fi
Inventor
Eduardo Pirotsky
Georges Dive
Jean-Jacques Godfroid
Francoise Heymans
Pierre Braquet
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of FI894812A0 publication Critical patent/FI894812A0/fi
Publication of FI894812L publication Critical patent/FI894812L/fi
Publication of FI96854B publication Critical patent/FI96854B/fi
Application granted granted Critical
Publication of FI96854C publication Critical patent/FI96854C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI894812A 1988-10-11 1989-10-11 Menetelmä valmistaa farmakologisesti arvokkaita 2-karbonyylisubstituoituja N,N'-di(trimetoksibentsoyyli)piperatsiineja FI96854C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888823775A GB8823775D0 (en) 1988-10-11 1988-10-11 New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823775 1988-10-11

Publications (4)

Publication Number Publication Date
FI894812A0 FI894812A0 (fi) 1989-10-11
FI894812L true FI894812L (fi) 1990-04-12
FI96854B FI96854B (fi) 1996-05-31
FI96854C FI96854C (fi) 1996-09-10

Family

ID=10644988

Family Applications (1)

Application Number Title Priority Date Filing Date
FI894812A FI96854C (fi) 1988-10-11 1989-10-11 Menetelmä valmistaa farmakologisesti arvokkaita 2-karbonyylisubstituoituja N,N'-di(trimetoksibentsoyyli)piperatsiineja

Country Status (33)

Country Link
US (1) US4923870A (fi)
JP (1) JPH0635452B2 (fi)
KR (1) KR970004912B1 (fi)
AR (1) AR245110A1 (fi)
AT (1) AT395423B (fi)
AU (1) AU618220B2 (fi)
BE (1) BE1003519A3 (fi)
CA (1) CA1320958C (fi)
CH (1) CH679859A5 (fi)
DE (1) DE3933881C2 (fi)
DK (1) DK500389A (fi)
DZ (1) DZ1365A1 (fi)
ES (1) ES2018403A6 (fi)
FI (1) FI96854C (fi)
FR (2) FR2637500B1 (fi)
GB (2) GB8823775D0 (fi)
GR (1) GR1000343B (fi)
HK (1) HK47592A (fi)
IE (1) IE62011B1 (fi)
IN (1) IN173325B (fi)
IT (1) IT1237088B (fi)
LU (1) LU87604A1 (fi)
MA (1) MA21652A1 (fi)
MY (1) MY106235A (fi)
NL (1) NL8902520A (fi)
NO (1) NO176180C (fi)
NZ (1) NZ230927A (fi)
OA (1) OA09139A (fi)
PT (1) PT91941B (fi)
SE (1) SE505239C2 (fi)
SG (1) SG41292G (fi)
TN (1) TNSN89110A1 (fi)
ZA (1) ZA897554B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
GB8908587D0 (en) * 1989-04-15 1989-06-01 Scras Societe De Conseils De R New 2-substituted n,n'-ditrimethoxybenzoyl piperazines
WO1992020661A1 (en) * 1991-05-22 1992-11-26 Merck & Co., Inc. N, n-diacylpiperazines
US5344830A (en) * 1992-12-10 1994-09-06 Merck & Co., Inc. N,N-diacylpiperazine tachykinin antagonists
US5348955A (en) * 1993-06-22 1994-09-20 Merck & Co., Inc. N,N-diacylpiperazines
FR2780649B1 (fr) 1998-07-06 2001-03-09 Univ Paris Vii Denis Diderot Derives de la piperazine pour l'inhibition de la replication du virus de l'immunodeficience humaine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3186993A (en) * 1962-06-07 1965-06-01 Ethyl Corp alpha, alpha'-(1, 4-piperazinediyl) bis (3, 5-dialkyl-4-hydroxythiobenzaldehyde) compounds
GB1243991A (en) * 1968-06-10 1971-08-25 Ici Ltd Piperidine, morpholine and piperazine derivatives
FR2209560A1 (en) * 1972-12-07 1974-07-05 Degussa N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin
DE2423847A1 (de) * 1973-05-28 1975-01-02 Ciba Geigy Ag Neue sulfamoylbenzoesaeureamide
GB8427735D0 (en) * 1984-11-02 1984-12-12 Fujisawa Pharmaceutical Co Piperazine compound
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
DE3636278A1 (de) * 1986-10-24 1988-05-05 Hoechst Ag Herbizide mittel auf der basis von cyclischen (alpha)-iminocarbon-saeureaniliden sowie neue (alpha)-iminocarbonsaeureanilide und verfahren zu ihrer herstellung
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use

Also Published As

Publication number Publication date
GR1000343B (el) 1992-06-25
NO176180B (no) 1994-11-07
KR900006309A (ko) 1990-05-07
ZA897554B (en) 1990-07-25
GB8823775D0 (en) 1988-11-16
SE8903312L (sv) 1990-04-12
JPH02223565A (ja) 1990-09-05
GB2223753A (en) 1990-04-18
NO894038D0 (no) 1989-10-10
IT8921992A1 (it) 1991-04-11
CH679859A5 (fi) 1992-04-30
FR2637500A1 (fr) 1990-04-13
DZ1365A1 (fr) 2004-09-13
IT8921992A0 (it) 1989-10-11
AR245110A1 (es) 1993-12-30
NO176180C (no) 1995-02-15
NL8902520A (nl) 1990-05-01
US4923870A (en) 1990-05-08
SE505239C2 (sv) 1997-07-21
KR970004912B1 (ko) 1997-04-08
AU618220B2 (en) 1991-12-12
NZ230927A (en) 1991-01-29
FI96854B (fi) 1996-05-31
SG41292G (en) 1992-06-12
ES2018403A6 (es) 1991-04-01
FR2637593B1 (fr) 1992-06-05
OA09139A (fr) 1991-10-31
GR890100647A (en) 1990-11-29
DE3933881C2 (de) 1994-06-30
FI894812A0 (fi) 1989-10-11
IE62011B1 (en) 1994-12-14
HK47592A (en) 1992-07-10
IE893258L (en) 1990-04-11
FR2637500B1 (fr) 1992-06-05
GB2223753B (en) 1992-01-02
DK500389D0 (da) 1989-10-10
FR2637593A1 (fr) 1990-04-13
FI96854C (fi) 1996-09-10
BE1003519A3 (fr) 1992-04-14
MY106235A (en) 1995-04-29
MA21652A1 (fr) 1990-07-01
AT395423B (de) 1992-12-28
CA1320958C (en) 1993-08-03
AU4268889A (en) 1990-04-26
PT91941B (pt) 1995-05-31
DK500389A (da) 1990-04-12
LU87604A1 (fr) 1990-02-07
NO894038L (no) 1990-04-17
ATA234689A (de) 1992-05-15
DE3933881A1 (de) 1990-04-12
JPH0635452B2 (ja) 1994-05-11
IT1237088B (it) 1993-05-18
GB8922870D0 (en) 1989-11-29
PT91941A (pt) 1990-04-30
TNSN89110A1 (fr) 1991-02-04
IN173325B (fi) 1994-04-02
SE8903312D0 (sv) 1989-10-09

Similar Documents

Publication Publication Date Title
FI890282L (fi) Menetelmä terapeuttisesti käyttökelpoisten 23,24-didehydro-25-hydroksikalsiferolijohdannaisten valmistamiseksi
FI891806L (fi) Menetelmä valmistaa farmakologisesti arvokasta bentso/5,6/sykloheptapyridiiniä
EP0248594A3 (en) Pharmacologically active 1,5-diaryl-3-substituted-pyrazopharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same les and method for synthesizing the same
FI893226L (fi) Menetelmä valmistaa farmakologisesti arvokasta bentsodiatsepiinia
FI891338A0 (fi) Parannus menetelmään 2',3'-dideoksi-2',3'-didehydronukleosidien valmistamiseksi
FI893170L (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi
FI873350A7 (fi) Menetelmä terapeuttisesti käyttökelpoisten 1,4-dihydropyridiinijohdannaisten valmistamiseksi
FI903752A7 (fi) Menetelmä 1,2,3,4-tetrahydro-9-akridiiniamiinin johdannaisten valmistamiseksi
FI895389A7 (fi) Menetelmä 3,5-dimetyyli-4-metoksipyridiinijohdosten valmistamiseksi sekä uusi välituote näitä varten
PT87717A (pt) Process for preparing 2,4-thiazolidinedione derivatives
FI880467A7 (fi) Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 3,4-dihydro-2H-bentsopyraanien valmistamiseksi
FI884660L (fi) Menetelmä terapeuttisesti aktiivisten 2,2-dimetyylikromeenijohdannaisten valmistamiseksi
FI894546A7 (fi) Menetelmä uusien 2'-halogeenimetylideeni-, 2'-etenylideeni- ja 2'-etynyyliadenosiinijohdannaisten valmistamiseksi
FI896075A7 (fi) Menetelmä 4,5,6,7-tetrahydrobentsimidatsolijohdosten valmistamiseksi
FI894812L (fi) Menetelmä valmistaa farmakologisesti arvokkaita 2-karbonyylisubstituoituja N,N'-di(trimetoksibentsoyyli)piperatsiineja
DK360888D0 (da) 3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater
FI901277A7 (fi) 2,5,6,7-tetranor-4,8-inter-m-fenyleeni PG1z-johdannaisia
FI891111A7 (fi) Menetelmä 1,4-dihydropyridiinijohdannaisten valmistamiseksi
KR860005812A (ko) 4,4-디알킬-2-아제티디논의 제조 방법
FI893121L (fi) Menetelmä farmakologisesti aktiivisten 6,21-dimetyyli-19-norprogesteronijohdannaisten valmistamiseksi
BG90160A (bg) Метод за получаване на 4'-деметилепиподофилотоксин- глюкозиди
FI893250A7 (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten 1,4-diatsepiinijohdannaisten valmistamiseksi
PL268592A1 (en) Method for manufacturing new 2,6-diamine-3-halogenbenzylpyridine derivatives
FI894813L (fi) Menetelmä terapeuttisesti aktiivisten 2-metoksikarbonyylisubstituoitujen N,N'-di(trimetoksibentsoyyli)piperatsiinijohdannaisten valmistamiseksi
FI93010B (fi) Menetelmä 1,5-bentsotiatsepiinijohdannaisten valmistamiseksi

Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: SOCIETE DE CONSEILS DE RECHERCHES ET D APPLICATION

MA Patent expired