FI883812A7 - 4'-deshydroxiepipodofyllotoxin -glukosider, syntes och anvaendning. - Google Patents

4'-deshydroxiepipodofyllotoxin -glukosider, syntes och anvaendning.

Info

Publication number: FI883812A7
Authority: FI; Finland
Prior art keywords: glucosider; deshydroxiepipodophyllotoxin; syntes; och anvaendning; anvaendning
Prior art date: 1987-08-20

Application number

FI883812A

Other languages

English (en)

Other versions

FI88167C (fi

FI88167B (fi

FI883812A0 (fi

Inventor

Mark G Saulnier

Dolatrai M Vyas

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-20

Filing date

1988-08-17

Publication date

1989-02-21

1988-08-17 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1988-08-17 Publication of FI883812A0 publication Critical patent/FI883812A0/fi

1989-02-21 Publication of FI883812A7 publication Critical patent/FI883812A7/fi

1992-12-31 Application granted granted Critical

1992-12-31 Publication of FI88167B publication Critical patent/FI88167B/fi

1993-04-13 Publication of FI88167C publication Critical patent/FI88167C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FI883812A 1987-08-20 1988-08-17 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4'-deshydroxiepipodofyllotoxinglukosider och mellanprodukter FI88167C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/087,355 US4868291A (en)	1987-08-20	1987-08-20	4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
US8735587		1987-08-20

Publications (4)

Publication Number	Publication Date
FI883812A0 FI883812A0 (fi)	1988-08-17
FI883812A7 true FI883812A7 (fi)	1989-02-21
FI88167B FI88167B (fi)	1992-12-31
FI88167C FI88167C (fi)	1993-04-13

Family

ID=22204690

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI883812A FI88167C (fi)	1987-08-20	1988-08-17	Foerfarande foer framstaellning av terapeutiskt anvaendbara 4'-deshydroxiepipodofyllotoxinglukosider och mellanprodukter

Country Status (16)

Country	Link
US (1)	US4868291A (fi)
EP (1)	EP0304086B1 (fi)
JP (1)	JPS6468394A (fi)
KR (1)	KR900006235B1 (fi)
AT (1)	ATE84792T1 (fi)
AU (1)	AU622869B2 (fi)
CA (1)	CA1317290C (fi)
DE (1)	DE3877658T2 (fi)
DK (1)	DK467288A (fi)
FI (1)	FI88167C (fi)
GR (1)	GR3006943T3 (fi)
IL (1)	IL87475A (fi)
NO (1)	NO167206C (fi)
NZ (1)	NZ225728A (fi)
PT (1)	PT88312B (fi)
ZA (1)	ZA884070B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4965348A (en) *	1989-05-19	1990-10-23	Bristol-Myers Company	Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) *	1989-06-07	1991-07-30	Bristol-Myers Company	Acylated derivatives of etoposide
IT1243340B (it) *	1990-07-13	1994-06-10	Crinos Industria Farmaco	Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio
US6207673B1 (en)	1997-03-12	2001-03-27	The University Of North Carolina At Chapel Hill	Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) *	1997-10-02	2000-04-18	The Board Of Regents Of The University Of Nebraska	Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
KR100442558B1 (ko) *	1999-05-31	2004-07-30	박경한	손톱깎이가 형성된 포켓툴
AR027687A1 (es) *	2000-03-22	2003-04-09	Yakult Honsha Kk	Procedimiento para preparar camptotecina
KR100434033B1 (ko) *	2000-12-01	2004-06-04	박경한	손톱깎이

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US608815A (en) *		1898-08-09		Wagon-pole coupling
GB823068A (en) *	1955-05-13	1959-11-04	Sandoz Ltd	Condensation products from glucosides
NL6613143A (fi) *	1965-09-21	1967-03-22
CH464957A (de) *	1965-12-14	1968-11-15	Sandoz Ag	Verfahren zur Herstellung eines neuen Glucosids
EP0111058B1 (en) *	1982-11-26	1987-11-04	Nippon Kayaku Kabushiki Kaisha	Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
JPS6032799A (ja) *	1983-07-29	1985-02-19	Microbial Chem Res Found	新規４′−デメチル−４−エピポドフィロトキシン誘導体
JPS60246393A (ja) *	1984-05-22	1985-12-06	Nippon Kayaku Co Ltd	エトポシドの新規製造法
US4609644A (en) *	1984-06-15	1986-09-02	St. Jude Children's Research Hospital	Epipodophyllotoxinquinone glucoside derivatives, method of production and use
JPS61227590A (ja) *	1985-04-02	1986-10-09	Microbial Chem Res Found	新規４′−デメチル−４−エピポドフイロトキシン誘導体
ZA886810B (en) *	1987-12-18	1989-08-30	Bristol Myers Co	Epipodophyllotoxin glucoside 4'-acyl derivatives

1987
- 1987-08-20 US US07/087,355 patent/US4868291A/en not_active Expired - Fee Related
1988
- 1988-06-08 ZA ZA884070A patent/ZA884070B/xx unknown
- 1988-07-19 CA CA000572400A patent/CA1317290C/en not_active Expired - Fee Related
- 1988-08-08 NZ NZ225728A patent/NZ225728A/en unknown
- 1988-08-17 IL IL87475A patent/IL87475A/xx unknown
- 1988-08-17 FI FI883812A patent/FI88167C/fi not_active IP Right Cessation
- 1988-08-19 KR KR1019880010570A patent/KR900006235B1/ko not_active Expired
- 1988-08-19 DE DE8888113524T patent/DE3877658T2/de not_active Expired - Fee Related
- 1988-08-19 JP JP63206224A patent/JPS6468394A/ja active Pending
- 1988-08-19 AT AT88113524T patent/ATE84792T1/de active
- 1988-08-19 PT PT88312A patent/PT88312B/pt not_active IP Right Cessation
- 1988-08-19 EP EP88113524A patent/EP0304086B1/en not_active Expired - Lifetime
- 1988-08-19 DK DK467288A patent/DK467288A/da not_active Application Discontinuation
- 1988-08-19 NO NO883703A patent/NO167206C/no unknown
- 1988-08-22 AU AU21196/88A patent/AU622869B2/en not_active Ceased
1993
- 1993-01-29 GR GR920402548T patent/GR3006943T3/el unknown

Also Published As

Publication number	Publication date
IL87475A0 (en)	1989-01-31
CA1317290C (en)	1993-05-04
NZ225728A (en)	1991-06-25
IL87475A (en)	1992-12-01
FI88167C (fi)	1993-04-13
DK467288D0 (da)	1988-08-19
NO883703L (no)	1989-02-21
KR900006235B1 (ko)	1990-08-27
FI88167B (fi)	1992-12-31
US4868291A (en)	1989-09-19
JPS6468394A (en)	1989-03-14
NO167206C (no)	1991-10-16
DK467288A (da)	1989-02-21
GR3006943T3 (fi)	1993-06-30
AU2119688A (en)	1989-02-23
PT88312B (pt)	1995-03-31
EP0304086A2 (en)	1989-02-22
DE3877658T2 (de)	1993-05-27
DE3877658D1 (de)	1993-03-04
AU622869B2 (en)	1992-04-30
ATE84792T1 (de)	1993-02-15
ZA884070B (en)	1989-04-26
PT88312A (pt)	1989-06-30
FI883812A0 (fi)	1988-08-17
KR890003792A (ko)	1989-04-18
EP0304086B1 (en)	1993-01-20
NO167206B (no)	1991-07-08
EP0304086A3 (en)	1990-09-05
NO883703D0 (no)	1988-08-19

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Legal Events

Date	Code	Title	Description
1995-03-13	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: BRISTOL-MYERS SQUIBB COMPANY