FI884240A0 - A process for the preparation of a pharmaceutical preparation for topical use - Google Patents
A process for the preparation of a pharmaceutical preparation for topical useInfo
- Publication number
- FI884240A0 FI884240A0 FI884240A FI884240A FI884240A0 FI 884240 A0 FI884240 A0 FI 884240A0 FI 884240 A FI884240 A FI 884240A FI 884240 A FI884240 A FI 884240A FI 884240 A0 FI884240 A0 FI 884240A0
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- topical use
- pharmaceutical
- pharmaceutical preparation
- proteins
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 230000003019 stabilising effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
The pharmaceutical preparations are for topical use, contain one or more stabilised therapeutically active proteins and, where appropriate, customary auxiliaries, vehicles and additives, and are prepared as described using physiologically tolerated hydrophobic substances for stabilising proteins.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3731255 | 1987-09-17 | ||
| DE19873731255 DE3731255A1 (en) | 1987-09-17 | 1987-09-17 | Stabilization of therapeutically active proteins in pharmaceutical preparations |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI884240A0 true FI884240A0 (en) | 1988-09-15 |
| FI884240L FI884240L (en) | 1989-03-18 |
| FI95770B FI95770B (en) | 1995-12-15 |
| FI95770C FI95770C (en) | 1996-03-25 |
Family
ID=6336244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI884240A FI95770C (en) | 1987-09-17 | 1988-09-15 | Process for the preparation of topical pharmaceutical product |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0307857B1 (en) |
| JP (1) | JP2783552B2 (en) |
| KR (1) | KR970008112B1 (en) |
| AT (1) | ATE126063T1 (en) |
| AU (1) | AU615473B2 (en) |
| CA (1) | CA1329121C (en) |
| DD (1) | DD274562A5 (en) |
| DE (2) | DE3731255A1 (en) |
| DK (1) | DK516288A (en) |
| ES (1) | ES2077559T3 (en) |
| FI (1) | FI95770C (en) |
| GR (1) | GR3017432T3 (en) |
| HU (1) | HU203045B (en) |
| IE (1) | IE70908B1 (en) |
| IL (1) | IL87778A (en) |
| NO (1) | NO179436C (en) |
| NZ (1) | NZ226209A (en) |
| PT (1) | PT88539B (en) |
| RU (1) | RU2093145C1 (en) |
| ZA (1) | ZA886903B (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5241925A (en) * | 1988-12-27 | 1993-09-07 | Dermamed | Apparatus and techniques for administering veterinary medicaments |
| US5332577A (en) * | 1988-12-27 | 1994-07-26 | Dermamed | Transdermal administration to humans and animals |
| US5130298A (en) * | 1989-05-16 | 1992-07-14 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| US5324521A (en) * | 1989-12-18 | 1994-06-28 | Dermamed | Systems for transdermal administration of medicaments |
| JPH0776527A (en) * | 1993-06-28 | 1995-03-20 | Hayashibara Biochem Lab Inc | Semi-solid preparation and method for producing the same |
| RU2132184C1 (en) * | 1998-12-16 | 1999-06-27 | Краснодарская научно-исследовательская ветеринарная станция | Method of preparing composition "zhiroform-plus" for treatment and prophylaxis of endometritis in cows |
| JP2004503593A (en) * | 2000-07-14 | 2004-02-05 | アラーガン、インコーポレイテッド | Compositions comprising a therapeutically active ingredient with increased solubility |
| RU2216313C2 (en) * | 2000-12-25 | 2003-11-20 | Савченков Сергей Николаевич | Curative-prophylactic cosmetic agent |
| RU2188665C1 (en) * | 2001-04-09 | 2002-09-10 | Щербакова Элеонора Григорьевна | Antiviral and antibacterial agent "interlisin" |
| ITMI20031640A1 (en) * | 2003-08-08 | 2005-02-09 | Mipharm S P A | BASE FOR BIOADHESIVE GEL. |
| CU23432B6 (en) * | 2005-11-02 | 2009-10-16 | Ct Ingenieria Genetica Biotech | STABILIZED FORMULATIONS CONTAINING GAMMA AND ALFA INTERFERONS IN POTENTIAL PROPORTIONS |
| MX2012012776A (en) * | 2010-05-04 | 2013-04-19 | Viscogel Ab | Chitosan composition. |
| RU2431489C1 (en) * | 2010-05-25 | 2011-10-20 | Федеральное государственное учреждение "Российский научный центр рентгенорадиологии Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "РНЦРР Росмедтехнологий") | Method of treating chronic inflammatory bowel diseases |
| PT3638251T (en) | 2017-06-12 | 2024-05-22 | Lakewood Amedex Inc | Bisphosphocin gel formulations and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5413223A (en) * | 1977-07-01 | 1979-01-31 | Ricoh Co Ltd | Printer unit |
| GB2016015B (en) * | 1978-01-22 | 1982-05-06 | Hayashibara Co | Method of preparing interferon and preparations containing interferon |
| JPS5598118A (en) * | 1979-01-18 | 1980-07-25 | Hayashibara Takeshi | Preparation of type-2 interferon and drug containing the same |
| SE8204382L (en) * | 1981-07-21 | 1983-01-22 | Hayashibara Biochem Lab | PUT TO MAKE MALCELLY FACTOR AND USE THEREOF |
| CA1190148A (en) * | 1981-10-13 | 1985-07-09 | Samuel S. Asculai | Interferon-containing compositions |
| JPS5892622A (en) * | 1981-11-28 | 1983-06-02 | Sunstar Inc | Pharmaceutical preparation containing stably compounded interferon |
| US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
| JPS5910524A (en) * | 1982-07-08 | 1984-01-20 | Toray Ind Inc | Interferon composition and its preparation |
| JPS6061535A (en) * | 1983-08-24 | 1985-04-09 | エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト | pharmaceutical composition |
| EP0177342A3 (en) * | 1984-10-04 | 1987-12-02 | Genentech, Inc. | Oral formulation of therapeutic proteins |
| DE3603444A1 (en) * | 1986-02-05 | 1987-08-06 | Thomae Gmbh Dr K | PHARMACEUTICAL PREPARATIONS FOR STABILIZING INTERFERON ALPHA |
| US4822605A (en) * | 1986-02-18 | 1989-04-18 | Exovir, Inc. | Compositions and methods employing the same for the treatment of viral and cancerous skin lesions and the like |
-
1987
- 1987-09-17 DE DE19873731255 patent/DE3731255A1/en not_active Ceased
-
1988
- 1988-09-13 EP EP88114944A patent/EP0307857B1/en not_active Expired - Lifetime
- 1988-09-13 ES ES88114944T patent/ES2077559T3/en not_active Expired - Lifetime
- 1988-09-13 DE DE3854290T patent/DE3854290D1/en not_active Expired - Lifetime
- 1988-09-13 AT AT88114944T patent/ATE126063T1/en not_active IP Right Cessation
- 1988-09-15 FI FI884240A patent/FI95770C/en not_active IP Right Cessation
- 1988-09-16 DD DD88319876A patent/DD274562A5/en not_active IP Right Cessation
- 1988-09-16 HU HU884894A patent/HU203045B/en unknown
- 1988-09-16 AU AU22316/88A patent/AU615473B2/en not_active Expired
- 1988-09-16 NO NO884123A patent/NO179436C/en not_active IP Right Cessation
- 1988-09-16 IL IL87778A patent/IL87778A/en active Protection Beyond IP Right Term
- 1988-09-16 ZA ZA886903A patent/ZA886903B/en unknown
- 1988-09-16 PT PT88539A patent/PT88539B/en not_active IP Right Cessation
- 1988-09-16 IE IE281288A patent/IE70908B1/en not_active IP Right Cessation
- 1988-09-16 KR KR1019880011951A patent/KR970008112B1/en not_active Expired - Lifetime
- 1988-09-16 NZ NZ226209A patent/NZ226209A/en unknown
- 1988-09-16 CA CA000577614A patent/CA1329121C/en not_active Expired - Lifetime
- 1988-09-16 JP JP63232113A patent/JP2783552B2/en not_active Expired - Lifetime
- 1988-09-16 DK DK516288A patent/DK516288A/en not_active Application Discontinuation
-
1992
- 1992-04-24 RU SU925011455A patent/RU2093145C1/en active
-
1995
- 1995-09-18 GR GR950402557T patent/GR3017432T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL87778A0 (en) | 1989-03-31 |
| IE882812L (en) | 1989-03-17 |
| IE70908B1 (en) | 1997-01-15 |
| EP0307857B1 (en) | 1995-08-09 |
| DK516288D0 (en) | 1988-09-16 |
| JPH01102029A (en) | 1989-04-19 |
| ZA886903B (en) | 1990-05-30 |
| AU615473B2 (en) | 1991-10-03 |
| FI884240L (en) | 1989-03-18 |
| KR890004719A (en) | 1989-05-09 |
| NO884123D0 (en) | 1988-09-16 |
| ATE126063T1 (en) | 1995-08-15 |
| RU2093145C1 (en) | 1997-10-20 |
| EP0307857A1 (en) | 1989-03-22 |
| PT88539B (en) | 1992-11-30 |
| FI95770C (en) | 1996-03-25 |
| DD274562A5 (en) | 1989-12-27 |
| DE3731255A1 (en) | 1989-04-06 |
| JP2783552B2 (en) | 1998-08-06 |
| NO179436B (en) | 1996-07-01 |
| NZ226209A (en) | 1991-06-25 |
| CA1329121C (en) | 1994-05-03 |
| PT88539A (en) | 1988-10-01 |
| IL87778A (en) | 1993-05-13 |
| DK516288A (en) | 1989-03-18 |
| NO884123L (en) | 1989-03-20 |
| HU203045B (en) | 1991-05-28 |
| GR3017432T3 (en) | 1995-12-31 |
| KR970008112B1 (en) | 1997-05-21 |
| FI95770B (en) | 1995-12-15 |
| HUT47436A (en) | 1989-03-28 |
| ES2077559T3 (en) | 1995-12-01 |
| NO179436C (en) | 1996-10-09 |
| DE3854290D1 (en) | 1995-09-14 |
| AU2231688A (en) | 1989-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| FG | Patent granted |
Owner name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
|
| MA | Patent expired |